2021
DOI: 10.1016/j.psj.2020.10.040
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Evaluation of berberine efficacy in reducing the effects of aflatoxin B1 and ochratoxin A added to male broiler rations

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Cited by 30 publications
(36 citation statements)
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“…Similar studies have confirmed this result by Tong et al. (2020) ( Figure 2 B) and Malekinezhad et al. (2020) ( Figure 2 C).…”
Section: Gitsupporting
confidence: 86%
See 1 more Smart Citation
“…Similar studies have confirmed this result by Tong et al. (2020) ( Figure 2 B) and Malekinezhad et al. (2020) ( Figure 2 C).…”
Section: Gitsupporting
confidence: 86%
“…The arrows “→” indicate a intestinal pathological damage or breakage of broiler chickens received 50 µg of OTA/kg body weight/day for 21 d ( Tong et al., 2020 ). (C) Histological structures of the ileum at 42 d of age (magnification, 5×): negative control diet with normal epithelial cells in the apical region of villi; (D) diet contaminated with OTA; the villus height was decreased and the apical region of epithelial cells was shedding ( Malekinezhad et al., 2020 ). Abbreviation: OTA, ochratoxin A.…”
Section: Gitmentioning
confidence: 99%
“…The mechanism behind the adverse effects of ingested mycotoxins in BW of birds has not been fully elucidated; however, the aforementioned mycotoxins have been associated with anorexia, listlessness, and metabolic changes, as a result of the liver damage and the decrease of the activity of digestive enzymes in combination with the decrease of nutrient digestibility due to the changes on the intestinal environment [ 33 , 34 ]. In addition, AFB 1 inhibits the digestibility of fats by reducing both enzyme activity and bile acid production necessary for their digestion and absorption [ 35 ].…”
Section: Discussionmentioning
confidence: 99%
“…Moghaddam et al (19) reported that administration of 50 and 100 mg/kg BBR (doses corresponding to our study), significantly reduced MDA in rats. Similarly, a recent investigation showed that BBR addition to aflatoxin B1 and ochratoxin A contaminated broilers diet, partially restored levels of MDA and GSH-Px activity (18).…”
Section: Biomarkers Of Oxidative Stress and Antioxidant Statusmentioning
confidence: 72%
“…Numerous reports in both cell culture (16) and animal models (17) have also highlighted the inhibitory effect of BBR on oxidative stress. The antioxidant activity of BBR is well documented as it altered the levels of antioxidant enzymes and oxidative stress markers such as glutathione (GSH), a lipid oxidation product that is reduced in oxidative stress, and malondialdehyde (MDA) that is increased in oxidative stress (18)(19)(20).…”
Section: Introductionmentioning
confidence: 99%