Evaluation of asthma control in children using Childhood—asthma control test (C-ACT) and Asthma therapy assessment questionnaire (ATAQ)

Somashekar, A. R.; Ramakrishnan, KG

doi:10.1007/s13312-017-1167-2

Cited by 14 publications

(17 citation statements)

References 9 publications

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“…the Global Initiative for Asthma guidelines. 1 The control group included 106 normal children (58 females; mean Ϯ SD age, 8.86 Ϯ 1.57 y) without a history of asthma or related respiratory symptoms as defined by the International Study of Childhood-Asthma Control Test and Asthma Therapy Assessment questionnaire 15 recruited from the First Affiliated Primary School of Zhengzhou University. None of the subjects had a respiratory infection for at least 1 month before study inclusion.…”

Section: What This Paper Contributes To Our Knowledgementioning

confidence: 99%

Curvilinearity of a Maximum Expiratory Flow-Volume Curve: A Useful Indicator for Assessing Airway Obstruction in Children With Asthma

Xiong

Dai²,

et al. 2019

Respir Care

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BACKGROUND: Lung function parameters are used as signs in the diagnosis and evaluation of asthma; however, their sensitivity and specificity are not ideal. We calculated and combined angle ␤ with lung function parameters to identify the ideal indicator. OBJECTIVE: We aimed to identify an ideal indicator for evaluating the severity of airway obstruction in children with asthma. METHODS: In total, 151 school-age children diagnosed with asthma were selected as the asthma group, and 106 healthy children were selected as the control group. The subjects were divided into the exacerbation group, chronic persistent group, and clinical remission group. Furthermore, the subjects were classified into mild and moderate groups or severe and critical groups. Angle ␤ was calculated in each group. A receiver operating characteristic curve analysis was performed to determine the cutoff values of angle ␤ and lung function parameters that together provided high sensitivity and specificity for airway obstruction evaluation in children with asthma. RESULTS: The mean value of angle ␤ in the asthma group was significantly smaller than that in the control group (178.18°and 196.72°, respectively, P < .001). More exacerbations or greater severity corresponded to smaller angle ␤ values (P < .001). The best cutoff value of angle ␤ was 189.43°, and the area under the receiver operating characteristic curve of angle ␤ was 0.877, which is greater than the area under the receiver operating characteristic curve of FEV 1 , forced expiratory flow (FEF) at 75% vital capacity (FEF 25%), and FEF at 50% vital capacity (FEF 50%), but smaller than the area under the receiver operating characteristic curve of FEF 75% and FEV 1 /FVC%. Interestingly, combining these measures can enhance the sensitivity and specificity in assessing airway obstruction. CONCLUSIONS: Angle ␤ was a useful indicator for assessing airway obstruction. Furthermore, angle ␤ combined with FEV 1 , FEV 1 /FVC%, FEF 25% , FEF 50% , and FEF 75% can enhance the sensitivity and specificity of airway obstruction evaluations.

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Section: What This Paper Contributes To Our Knowledgementioning

confidence: 99%

Curvilinearity of a Maximum Expiratory Flow-Volume Curve: A Useful Indicator for Assessing Airway Obstruction in Children With Asthma

Xiong

Dai²,

et al. 2019

Respir Care

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“…The study remained on 56 patients who met the criteria: use of IC regularly, either alone or in combination with long-acting beta 2 agonist, at least 3 months and had none of the conditions (associated pulmonary comorbidity, inadequately performed spirometric tests, or incorrect completion of the C-ACT/ACT questionnaire). In the study sample (56 children) , it was found a predominance of males (58.9%) and a median age of 12 (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) years. There was a statistical association between FEV1 and GINA values (p <0.01), as well as between FEV1 values and those of C-ACT/ACT scores (p <0.01) in relation to controlled and untreated patients.…”

Section: Why Was This Study Done?mentioning

confidence: 77%

“…Resultados: Do total de prontuários avaliados (72), 16 crianças foram excluídas por não preencherem os critérios exigidos para realização da espirometria. A amostra estudada (56 crianças) apresentou predomínio do sexo masculino (58,9%) e mediana de idade igual a 12 (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) anos. Observou-se associação entre os valores de VEF1 e o GINA (p<0,01).…”

Section: Introductionunclassified

Is there an association between the value of forced expiratory volume in the 1st second, the Asthma Control Test and a Control Framework by Global Initiative for asthma in asthmatic children and adolescents treated with inhaled corticosteroids?

Taglia-Ferre¹,

Lisboa

Salviano

et al. 2019

jhgd

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Objective: Evaluate the presence of association between the classification of the level of asthma control, using the method proposed by the Global Initiative for Asthma (GINA), the Asthma Control Test (ACT)/Childhood-ACT and the forced expiratory volume in the 1st second (FEV1), in asthmatic children and adolescents treated with inhaled corticosteroids, followed up at the National Institute of Women's, Children's and Adolescents' Health FernandesFigueira of the Oswaldo Cruz Foundation (IFF / FIOCRUZ). Method: A cross-sectional study was carried out with a review of the medical records of all children between 7 and 17 years of age followed up at the Asthma Outpatient Clinic and referred to the Respiratory Insertion Test (PFR) sector between March 2013 and September 2014. In the same day were applied the C-ACT/ACT questionnaires, an asthma control method proposed by the GINA and the FEV1 value in a spirometrictest. Results: From the total number of records evaluated (72), 16 children were excluded because they did not meet the required criteria for performing spirometry. The sample studied (56 children) was predominantly male (58.9%) and median age was 12 (7-17) years. It was observed an association between FEV1 and GINA values ??(p <0.01). Conclusion: The results found in this study indicate that FEV1 measurement is a useful component among the instruments for assessing clinical control of asthma by GINA.

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“…Although the studies comparing the compatibility of them and GINA criteria for the assessment of asthma control had challenging results. [6][7][8][9][10] In the study of Koolen et al, they compared PACT and ACT with GINA criteria in assessing asthma control of children with similar study design. 10 They found an AUC of ROC curve analyses for PACT 0.89 and ACT 0.92 which were higher than our study(0.79 and 0.86 in our study, respectively).…”

Section: Discussionmentioning

confidence: 99%

“…Neverthless, the compatibility and cut-off values of ACT/PACT which reflect the patients' and/or caregivers' perception of asthma symptoms according to GINA based control measurement for children are challenging. [6][7][8][9][10] Although lung function does not correlate strongly with asthma symptoms in children, forced expiratory volume in 1 second(FEV 1 ) is requested to be used by GINA, because of the relation with asthma control and future exacerbations. 1 So, it should be used while regular asthma follow-up as a component of evaluation of asthma control based on GINA criteria.…”

Section: Introductionmentioning

confidence: 99%

Determining pediatric asthma control in real-life: Comparison of Pediatric Asthma Control Test, Asthma Control Test, Fractional exhaled nitric oxide, Pediatric Asthma Quality of Life Questionnaire and Lung function with GINA criteria

Akan¹,

Mısırlıoğlu²,

Civelek³

et al. 2020

Preprint

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Background Guidelines as Global Initiative for Asthma(GINA) recommend disease control as the mainstay of asthma management. The performance of the tools assessing in asthma control is challenging in real-life. Methods Children and adolescents with asthma followed at a tertiary research hospital were enrolled in the study after evaluation of adherence to treatment. Asthma Control Test(ACT)/Pediatric Asthma Control Test(PACT), Pediatric Asthma Quality of Life Quesstionnaire(PAQLQ), fractional exhaled nitric oxide(FeNO) and lung function were evaluated. Patients were examined by asthma specialists blinded to the results of the tools and their control status were evaluated based on GINA. Results The median age(interquartile range,IQR) of the patients was 10.7(8.4-12.9) years, 57.9% were boys. Of 228 children, 84.2%, 9.6% and 6.1% had "well-controlled", "partially-controlled" and "uncontrolled" asthma, respectively. The patients with "partially-controlled " and "uncontrolled" asthma were grouped as "not well-controlled". The cut-off levels were 22, 21 and 5.9 for PACT, ACT and PAQLQ for determining "well-controlled" asthma(p<0.001). With these cut-off values, ACT had the higher compatibility with GINA than PACT and PAQLQ(κ=0.221, 0.473 and 0.150, respectively, p<0.001). Correctly classified patients with PACT, ACT and PALQLQ based on GINA with these cut-off levels were 93(64.1%), 63(75.9%) and 139(62.9%), respectively. FeNO and lung function were unsuccessful at revealing control status according to GINA. Conclusion ACT is better than PACT at compatibility with GINA. Probably, it is because older children have a longer recall period than younger ones. It would be better to use these tools for each patient by comparing their own scores in real-life, instead of cut-off values.

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Evaluation of asthma control in children using Childhood—asthma control test (C-ACT) and Asthma therapy assessment questionnaire (ATAQ)

Cited by 14 publications

References 9 publications

Curvilinearity of a Maximum Expiratory Flow-Volume Curve: A Useful Indicator for Assessing Airway Obstruction in Children With Asthma

Curvilinearity of a Maximum Expiratory Flow-Volume Curve: A Useful Indicator for Assessing Airway Obstruction in Children With Asthma

Is there an association between the value of forced expiratory volume in the 1st second, the Asthma Control Test and a Control Framework by Global Initiative for asthma in asthmatic children and adolescents treated with inhaled corticosteroids?

Determining pediatric asthma control in real-life: Comparison of Pediatric Asthma Control Test, Asthma Control Test, Fractional exhaled nitric oxide, Pediatric Asthma Quality of Life Questionnaire and Lung function with GINA criteria

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