Propolis is a highly complex resinous substance collected by honeybees from the fresh plant buds or secretions and mixed with beeswax and utilized for different purposes in the hive and includes more than 300 primary compounds (Guo et al., 2015). The human medicine has been interested in this product, used for several purposes, such as paving the hive surfaces, filling the cracks and fractures, polishing the honeycomb cells, narrowing and widening the hive entrance, and coating and isolating possible disease agents, for thousands of years, and it was used in several areas, including mummification and to treat mouth sores (Fokt et al., 2010; Can et al., 2015). Various alcohol and water-based extracts prepared with propolis are used for various purposes as food additives and supplements. Demand for propolis products, such as skin lotions, beauty creams and balms, massage oils and lotions, shampoos, soaps, lipsticks, gums, toothpaste, sunscreens and lozenges, increases every day. This natural bee product is an indispensable apitherapy agent, which has a wide biological activity spectrum due to antibacterial, antioxidant, antifungal, antiviral, anti-inflammatory and antitumoral properties (Kujumgiev et al., 1999; Amini-Sarteshnizi et al., 2015). Although the composition of propolis varies based on the plant flora, collection period, hive type, beekeeper performance and hive condition, it usually includes approximately 40-50% balsam, 20-30% wax, 5-10% essential oils, 1-5% pollen and 5% various organic compounds (Pietta et al., 2002; Bankova et al., 2019). The vast majority of the balsamic content that includes the active propolis ingredients consist of various polyphenols (phenolic acids, flavonoids, tannins, and their esters), terpenes, volatile organic compounds and various alcohols (Gülçin et al., 2010; Miguel et al., 2010; Baltas et al., 2016). The global demand for raw propolis products has been increasing, and several studies have been investigating methods to collect higher propolis yields. Previous studies on the factors that affect propolis production are limited, and these studies suggested that the main factors that affect the chemical composition of propolis were bee race, climate, production season and production method (trap structure) (Bankova et al., 2000; Abu Fares et al., 2008; Pujirahayu et al., 2014). An important factor that affects per hive production was the presence of a forest in the vicinity. In a study conducted in Europe, it was reported that annual production, which was around 50-150 g per colony, generally varied within the range of 10-300 g (Abu Fares et al., 2008). Thus, in the present study, the variations in propolis production and quality were investigated based on the collection period and the hive type in the Van lakeshore flora, Turkey. In this study, the propolis yield and quality were investigated using wooden, plastic and styrofoam hives. 2 Materials and methods In this study, where wooden, styrofoam and plastic hives were used in accordance with the Food Codex, Apis mellifera ...