Evaluation of antimicrobial efficacy of quaternized poly[bis(2-chloroethyl)ether-<i>alt</i>-1,3-bis[3-(dimethylamino)propyl]urea] against targeted pathogenic and multi-drug-resistant bacteria

Kumar, Bipul; Mathur, Anurag; Pathak, Rajiv; Sardana, Kabir; Gautam, Hemant K.; Kumar, Pradeep

doi:10.1177/0883911515627473

Cited by 13 publications

(13 citation statements)

References 40 publications

(67 reference statements)

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“…The cationization of cotton has been researched for more than 50 years (Correia et al 2020 ) but has grown especially at the beginning of the 2000s, after the after process improvement by Hauser and Tabba ( 2001 ). Besides, cationic cellulose is widely applied in other fields, such as papermaking (Gao et al 2016 ; Odabas et al 2016 , 2017 ; Aguado et al 2018 ), cosmetics (Bujak et al 2020 ), adsorbents (Pei et al 2013 ; Lawchoochaisakul et al 2021 ), flocculants (Yan et al 2009 ; Sirviö et al 2011 ) and antimicrobial agents (Chaker and Boufi 2015 ; Kumar et al 2016 ). Cationic agents are also used to prepare fabrics with functional properties, such as UV protection, hydrophobicity, and conductive textiles (Wang and Hauser 2010 ; Kamal Alebeid and Zhao 2015 ; Sahito et al 2015 , 2016 ; Abd El-Hady et al 2020 ; Liu et al 2020 ).…”

Section: Introductionmentioning

confidence: 99%

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Preparation of cationic cotton through reaction with different polyelectrolytes

et al. 2021

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Graphic abstract Cationization of cotton fabrics was performed by exhaustion procedure utilizing four different reagents provided with quaternary ammonium groups: poly diallyldimethylammonium chloride (PDDACl), poly acrylamide-co-diallyldimethylammonium chloride (PAcD), poly[bis(2-chloroethyl) ether-alt-1,3-bis[3-(dimethylamino)propyl]urea] quaternized (P42) and 3-chloro-2-hydroxypropyl trimethyl ammonium chloride (CHPTAC). Pretreated samples were dyed using Reactive Red 195 dye. The cationic fabrics were analyzed by colorimetric and fastness properties, zeta potential, SEM, FTIR and an estimate of the bactericidal effect. Cationic cotton treated with PDDACl and CHPTAC showed a higher affinity for the reactive dye, with color strength (K/S) values varying from 41 to 48, against 32 for conventional dyeing. P42 presented competitive results with K/S of 27–28. The cationic dyeing considerably reduced the amount of effluent, especially for the CHPTAC samples, which requires a single washing bath for complete removal of unfixed dye. The PDDACl and P42 samples presented bactericidal activity. Supplementary Information The online version contains supplementary material available at 10.1007/s10570-021-04260-4.

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Section: Introductionmentioning

confidence: 99%

“…Hence, it may be a candidate for cotton cationization. P42 has antimicrobial efficacy and non-toxic behavior reported (Kumar et al 2016 ). A sustainable approach with plasma treatment and cationization of cotton at the greige stage using P42 was recently reported by the same research group (Correia et al 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Preparation of cationic cotton through reaction with different polyelectrolytes

et al. 2021

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“…In this research, the cationization of cellulose was performed by using a novel cationic agent: propyl]urea] quaternized (P42), also known as Polyquaternium-2. P42 is a commercially available hypotoxic cationic polymer, has antimicrobial activity and has been commonly used in the cosmetic industry (Chen et al 2016;Kumar et al 2016). The monomeric unit of P42 contains two quaternary ammonium groups, which is essential for cellulose cationization as it provides cationic groups (Roy Choudhury 2014).…”

Section: Introductionmentioning

confidence: 99%

Surface functionalization of greige cotton knitted fabric through plasma and cationization for dyeing with reactive and acid dyes

et al. 2021

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Dyeing cotton fabrics with anionic dyes produces high e uent loads and requires a considerable amount of water and energy due to the electrostatic repulsion with cellulose. Therefore, several approaches have been researched to increase the e cacy of cotton dyeing. One is the cationization, which adds cationic sites to the cellulose. Another is the treatment of the cotton surface with plasma. In this paper, the combination of both techniques was investigated. Two commercially available cationic agents were used: 3-chloro-2-hydroxypropyl trimethyl ammonium chloride (CHPTAC) and poly[bis(2-chloroethyl) etheralt-1,3-bis[3-(dimethylamino)propyl]urea] quaternized, a novel cationic agent also known as Polyquaternium2 (P42). The plasma treatment was performed using a dielectric barrier discharge atmospheric plasma facility, helium was used as seed gas and 1.5 % of oxygen was injected. The cationization and plasma treatment were performed on greige cotton fabric, an innovative and sustainable approach that eliminates conventional scouring and bleaching processes. The cationic and plasma treated samples were dyed using Reactive Red 195 and Acid Blue 260 dyes. The effect of the treatments was evaluated by different characterization techniques such as X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR) and atomic force microscopy (AFM). The plasma treatment slightly increased the light fastness for some samples, but the cationization tends to prevail over the plasma treatment. The best results were attributed to the samples pretreated by CHPTAC, which presented the highest K/S and lowest unlevelness for samples dyed with reactive and acid dyes. CHPTAC is the most common cationic agent for textiles, but its industrial use is limited due to safety criticisms. The combination between plasma and P42 resulted in the same color strength as the conventional reactive dyeing. Therefore, this approach offers a safer alternative to the conventional cationization process.

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“…Several studies, based on these strategies, have been taken up and demonstrated their efficacy in the literature. [36][37][38][39][40][41][42][43] Recently, these concerns have also been addressed to an extent by conjugation with polyethylene glycol (PEG). Pegylation is one of the commonly used techniques to improve in vivo efficacy of peptides, proteins, and polymers.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of antimicrobial activity and cytotoxicity of pegylated aminoglycosides

Ahmadi

Verma

Jha

et al. 2017

Journal of Bioactive and Compatible Polymers

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Here, in this study, we have investigated the antibacterial activity and cytotoxicity of pegylated aminoglycosides (gentamicin, kanamycin, and neomycin). The antibacterial activity of pegylated aminoglycosides, prepared in two different ratios (1:1 and 1:2, aminoglycoside:polyethylene glycol), was determined against some common pathogens, namely, Gram-positive (Bacillus cereus, Staphylococcus aureus) and Gram-negative (Escherichia coli, Pseudomonas aeruginosa), by zone of inhibition and minimum inhibitory concentration assays. The activity of pegylated aminoglycosides was found to be decreased as compared to their respective native aminoglycosides. Moreover, aminoglycoside:polyethylene glycol (1:1) derivatives showed much higher activity as compared to aminoglycoside:polyethylene glycol (1:2) derivatives, that is, an increase in the content of polyethylene glycol decreased the activity considerably. This decrease in antibacterial activity was found to be the most prominent in Grampositive bacteria, S. aureus. On the other hand, pegylation significantly decreased the cytotoxicity as determined by hemolysis and MTT assays. These results advocate exploration of different types of crosslinkers consisting of a small degree of amphiphilicity, which could facilitate better interactions with the bacterial cell membranes and inhibit induction of bacterial resistance.

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Evaluation of antimicrobial efficacy of quaternized poly[bis(2-chloroethyl)ether-alt-1,3-bis[3-(dimethylamino)propyl]urea] against targeted pathogenic and multi-drug-resistant bacteria

Cited by 13 publications

References 40 publications

Preparation of cationic cotton through reaction with different polyelectrolytes

Preparation of cationic cotton through reaction with different polyelectrolytes

Surface functionalization of greige cotton knitted fabric through plasma and cationization for dyeing with reactive and acid dyes

Evaluation of antimicrobial activity and cytotoxicity of pegylated aminoglycosides

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