Evaluation of Antimicrobial Effect of the Pimpinella Anisumpolar Extract on Some Bacteria in Skin Diseases

Abstract

Background: Some pathogenic bacteria cause diseases under certain conditions, such as entry through the skin via a cut. Staphylococcus and Pseudomonas can be commonly found on the skin; yet, these species can potentially initiate skin infections. Considering the importance of these bacteria in skin infections and based on the world attraction to traditional treatment, the present study was conducted to determine the antibacterial effect of Pimpinella anisum polar extract on standard strains of Pseudomonas aeruginosa and Staphylococcus aureus. Methods: Antimicrobial effect of anisum's polar extract was determined by the well diffusion agar and microtitr plate for determining the minimum bactericidal concentration (MBC) and minimum inhibitory concentrations (MIC) on Staphylococcus aureus, Pseudomonas aeruginosa. Results: Inhibition zones were recorded for both bacteria in this study. The MIC/MBC assay showed that Pseudomonas aeruginosa bacteria had the highest susceptibility to the anisum's polar extract. Conclusions: Considering the antibacterial effects of the Pimpinella anisum extract, the extract of this plant can be studied as a treatment for skin infections.