Evaluation of Antimicrobial Activity of Cissus quadrangularis L. stem extracts against Avian Pathogens and Determination of its Bioactive Constituents using GC-MS

Abstract

The current study evaluates the antimicrobial activity and characterizes the chemical constituents of stems of Cissus quadrangularis L. using Gas Chromatography Mass Spectrophotometry (GC-MS). The disc diffusion method was employed to determine the antimicrobial activity of methanol, ethanol, aqueous and petroleum ether extracts of Cissus quadrangularis stems against avian microorganisms viz. Escherichia sp., Klebsiella sp., Salmonella sp, Staphylococcus sp., Pasturella sp. and Aspergillus sp. were isolated from layer chicken. Among the various extracts, methanol extract showed potential antimicrobial activity against avian microorganisms especially Escherichia sp. and least activity was noted against Aspergillus sp. followed by ethanol, petroleum ether and aqueous extracts also showed activity against the tested avian pathogens. Among all the bioactive compounds identified in the current study,

Gas Chromatography-Mass Spectrometry Analysis of Compounds Emitted by Pepper Yellow Leaf Curl Virus-Infected Chili Plants: A Preliminary Study

“…Among these compounds, there were antimicrobial and antiparasitic compounds emitted by the PYLCV-undetected pants. Cyclopentaneundecanoic acid, methyl ester (antimicrobial [65,87]), 12-methyl-E,E-2,13-octadecadien-1-ol (anti-microbial and anti-fungal agent…”

“…Among these compounds, there were antimicrobial and antiparasitic compounds emitted by the PYLCV-undetected pants. Cyclopentaneundecanoic acid, methyl ester (antimicrobial [65,87]), 12-methyl-E,E-2,13-octadecadien-1-ol (anti-microbial and antifungal agent [87,88]), and 2-piperidinone, N-[4-bromo-n-butyl]-(antimicrobial and an-tioxidant [80]) were emitted by UPJ, while 6-methylenebicyclo [3.2.0] hept-3-en-2-one (antiparasitic [77,89]) was emitted by UPS. However, the compounds were not found in the PYLCV-infected plants.…”

Network Pharmacology-Based Study to Uncover Potential Pharmacological Mechanisms of Korean Thistle (Cirsium japonicum var. maackii (Maxim.) Matsum.) Flower against Cancer

“…Urs-12-en-24-oic acid, 3-oxo-, methyl ester is categorized into boswellic acids used widely as anti-inflammatory agents, including as an anti-cancer treatment. Additionally, the boswellic acids have potent anti-cancer efficacy against diverse malignant cancers [ 49 , 50 ]. The KEGG pathway enrichment analysis of 24 targets suggested that a total of 20 signaling pathways were involved in cancer occurrence and development.…”

A New Ceramide from Cissus Aralioides Baker (Vitaceae) and its Antimicrobial Activity

“…C. aralioides which remains green throughout the year with branches and roots without any originality [5] is used in the traditional medicine in Cameroon as anti‐microbial and toxicological remedies against pathogenic microorganisms of the gastrointestinal and urogenital tracts [6] . Interest in giving scientific authentication and explanation to the biological activities of plants used in traditional medicines enforce their phytochemical and pharmacological investigations [4,7] . Bioactivity assays and isolation of various compounds have been carried out in a number of species from the genus Cissus and had shown impressive results [8,9] .…”

“…[6] Interest in giving scientific authentication and explanation to the biological activities of plants used in traditional medicines enforce their phytochemical and pharmacological investigations. [4,7] Bioactivity assays and isolation of various compounds have been carried out in a number of species from the genus Cissus and had shown impressive results. [8,9] Antimicrobial, anti-inflammatory, antiulcer, antioxidative, hepatoprotective properties are among the reported bioactivities, [4,[7][8][9] while the chemical constituents isolated mostly include lipids, stilbenes, terpenoids, steroids, alkaloids and phenolic compounds.…”