Evaluation of antifungal activity of six children's toothpaste on Candida albicans isolated from early childhood caries patients

Chandhru, T P; Anusha, V R; Peedikayil, Faizal C; Ahmed, M B Gufran; Kottayi, Soni; Narasimhan, Dhanesh

doi:10.4103/jisppd.jisppd_3_20

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…The other two clinical studies showed different results. Chandru et al (27) concluded that although A. vera toothpaste has antifungal activity, its antifungal activity was less than other commercial ones used by children. The antifungal activity of A. vera toothpaste was due to its active ingredients such as anthraquinone.…”

Section: Discussionmentioning

confidence: 99%

The Potential of Aloe vera as an Active Ingredient in Toothpaste Formulations: A Narrative Review

Nasiri

Shafaroudi

Moosazadeh

et al. 2021

Jundishapur J Nat Pharm Prod

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Context: Tooth brushing is a primary method to prevent the onset of oral diseases. Aloe vera is commonly used in dentistry as an herbal alternative due to its anti-inflammatory and anti-microbial actions; recently, it has been used in toothpaste formulations as an active agent. This review aimed to investigate the clinical effects of A. vera as an active ingredient in toothpaste formulations. Materials and Methods: The data used in this review was extracted from articles published until 2020. We searched official databases, including Scopus, PubMed, Google Scholar, Embase, and Science Direct, using the “Aloe vera”, “dentifrice”, and “toothpaste” keywords. After screening titles and abstracts, relevant studies were used for full-text review. Results: Although conflicting results have been reported on the usage of A. vera toothpaste in different studies, the majority of findings suggest that A. vera effectively reduces periodontal indices and removes different organisms, including Streptococcus mutans. However, the overall effects of this herbal toothpaste were found to be equal to those of other commercial toothpaste. Conclusions: Aloe vera toothpaste is as beneficial as other kinds of toothpaste. Therefore, it can be used as an adjunct agent in toothpaste due to its established effects on improving periodontal problems and reducing different oral cavity micro-organisms.

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Section: Discussionmentioning

confidence: 99%

The Potential of Aloe vera as an Active Ingredient in Toothpaste Formulations: A Narrative Review

Nasiri

Shafaroudi

Moosazadeh

et al. 2021

Jundishapur J Nat Pharm Prod

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Biofabrication of silver nanoparticles with Feijoa sellowiana tailored by box-behnken design: An eco-friendly approach to enhance antifungal properties in Children's toothpaste

Fazli,

Babaei,

Moazeni

et al. 2024

Journal of Drug Delivery Science and Technology

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Antimicrobial Activity of Children's Toothpaste on the Bacteria Causing Dental Caries

Taghdisi-Kashani¹,

Gholamshahi²,

Fathizadeh³

et al. 2022

Iran J Med Microbiol

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Background and Aim:Early childhood caries is one of the most common chronic diseases in children, affecting both oral and general health. Oral microorganisms are the most important causative agents associated with dental caries in children. The aim of this study was to compare the antimicrobial activity of common Iranian and non-Iranian children's toothpaste on the growth of four standard bacteria strains, including Streptococcus mutans, Streptococcus sanguinis, Lactobacillus acidophilus, and Enterococcus faecalis. Materials and Methods:In this study, six types of the most common Iranian and non-Iranian children toothpaste produced by different companies were prepared. Different concentrations of toothpaste were prepared according to the Clinical and Laboratory Standards Institute (CLSI) standard. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of Iranian and non-Iranian children's toothpaste were measured by the microbroth dilution method at ten different concentrations.Results: For the S. mutans bacteria, the lowest MIC was found in Misswake, Vi-One, and 2080 toothpaste. In the case of S. sanguinis and L. acidophilus bacteria, the lowest MIC was related to Frice toothpaste, and for E. faecalis bacteria, the lowest MICs were found for Misswake and 2080 toothpaste. Mann-Whitney U test also revealed that the inhibitory and bactericidal activities of Iranian children's toothpaste on the studied bacteria were not significantly different from those of non-Iranian children's toothpaste. Conclusion:In general, the antimicrobial activity of Iranian children's toothpaste was higher than non-that of Iranian samples. In addition, the MIC of 2080 and Frice toothpaste in the four bacteria examined was lower than in other used toothpaste. To prevent early tooth decay in children use of these two kinds of toothpaste is recommended.

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Evaluation of antifungal activity of six children's toothpaste on Candida albicans isolated from early childhood caries patients

Cited by 5 publications

References 17 publications

The Potential of Aloe vera as an Active Ingredient in Toothpaste Formulations: A Narrative Review

The Potential of Aloe vera as an Active Ingredient in Toothpaste Formulations: A Narrative Review

Biofabrication of silver nanoparticles with Feijoa sellowiana tailored by box-behnken design: An eco-friendly approach to enhance antifungal properties in Children's toothpaste

Antimicrobial Activity of Children's Toothpaste on the Bacteria Causing Dental Caries

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