Evaluation of analytical methods for determining pesticides in baby foods and adult duplicate-diet samples

Chuang, Jane C.; Weimer, Katherine H.; Chang, Joseph S; Boman, Lawrence E; Emon, Jeanette M. Van; Reed, Allan W

doi:10.1016/s0003-2670(01)01164-3

Cited by 52 publications

(19 citation statements)

References 3 publications

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“…Results obtained with wet carrots were not satisfactory, as most of the recoveries values were below 70%. The presence of water molecules in the matrix may (1) 34 (1) 34 (5) 29 (4) 48 (13) Trifluralin 47 (12) 45 (3) 51 (10) 26 (5) 22 (5) 17 (2) 37 (12) 43 (3) 26 (2) 41 (17) 28 (7) 26 (1) 17 (4) 29 (6) 34 (8) Dicloran…”

Section: Methods Validationmentioning

confidence: 99%

“…5 The majority of the studies concerning pesticides (by SRM or MRM) extraction using PLE are related to soil and sediment samples. [11][12][13] Regarding fresh vegetables samples there are only a few studies in the literature dealing with MRM analysis, even though analytical methods for this kind of samples are extremely important for food quality control. 11,14,15 Matrix solid phase dispersion (MSPD), a process for the extraction of target compounds from solid matrices was introduced by Barker et al 16 in 1989.…”

Section: Introductionmentioning

confidence: 99%

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Multiresidue determination of pesticides in carrots using pressurized liquid extraction and gas chromatography with mass spectrometry detector

Abad¹,

Winck²,

Silva³

et al. 2010

J. Braz. Chem. Soc.

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Neste estudo, 14 agrotóxicos (captan, clorotalonil, deltametrina, dicloran, fention, folpete, iprodiona, linurom, malationa, prometrina, procloraz, procimidona, triclorfom e trifluralina) foram usados no desenvolvimento de um método multiresíduos (MRM), utilizando extração de cenouras com líquido pressurizado (PLE). A etapa de clean-up foi realizada por dispersão da matriz em fase sólida (MSPD), sendo testados como material dispersante o Florisil, XAD-4, XAD-7 e C18. Diclorometano, acetato de etila e acetona foram empregados como solventes para PLE, a 75 ºC e 1.500 psi. As recuperações dos analitos para cenouras liofilizadas ficaram na faixa de 70 a 133%. Entretanto, os percentuais de recuperação obtidos para as cenouras úmidas não foram satisfatórios (< 70%). Os coeficientes de determinação das curvas analíticas situaram-se na faixa de 0,9821 a 0,9997; os limites de detecção (LOD) e de quantificação (LOQ) para os vários compostos investigados ficaram entre 0,0024-0,1968 mg kg -1 e entre 0,0072-0,5963 mg kg -1 , respectivamente.In this study, 14 pesticides (captan, chlorothalonil, deltamethrin, dicloran, fenthion, folpet, iprodione, linuron, malathion, prometryn, prochloraz, procymidone, trichlorphon and trifluralin) were employed for developing a multiresidue method (MRM) using pressurized liquid extraction (PLE). In situ clean-up was achieved using matrix solid phase dispersion (MSPD), where Florisil, XAD-4, XAD-7 and C18 were tested as dispersing material for carrot samples. Dichloromethane, ethyl acetate and acetone were used as solvents in a PLE unit at 75 ºC and 1,500 psi. Recovery was in the range of 70 to 133 %. Results obtained with wet carrots were not satisfactory, since most of the recovery values were below 70%. Determination coefficients of the analytical curves presented values between 0.9821 and 0.9970. Limits of detection (LOD) and quantification (LOQ) for the various components varied from 0.0024 to 0.1968 mg kg -1 , and 0.0072 to 0.5963 mg kg -1 , respectively. Keywords: multiresidue method, PLE, MSPD, carrots, GC/MS IntroductionIn the last few decades, pesticides have been used on an increasingly wider scale throughout the world. On account of the large number of active ingredients used in agricultural production, complex analytical procedures are required for the detection of a great number of possible compounds, with few number of extraction and clean-up steps. These compounds are characterized by their diversity, their different physical and chemical properties (polarity, solubility, pKa etc) and their low concentrations in real samples. 1 Some of the analytical methods aim to determine a single component (SRM) and others, more sophisticated, are capable of simultaneously determine more than one residue in a single analysis. These last ones are called pesticide multiresidue methods (MRM) and comprise a higher degree of analytical difficulty. Multiresidue methodology by definition requires determinative steps for separating analytes from one another so each one can be detected and measured ...

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Section: Methods Validationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Multiresidue determination of pesticides in carrots using pressurized liquid extraction and gas chromatography with mass spectrometry detector

Abad¹,

Winck²,

Silva³

et al. 2010

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

show abstract

“…Tao et al (2004) applied PFE for extracting DDT and its metabolites from wheat with hexane/acetone (1:1, v/v) at 120 o C and a pressure of 101 MPa. Moreno et al (2006) Chuang et al (2001) investigated the use of PFE for the analysis of pesticides in baby food but observed matrix interferences due to the high level of fat present in the samples. Although widely used as an initial extraction for solid samples, for trace analysis, postextraction procedures for analyte enrichment/concentration are often required.…”

Section: Pressurized Fluid Extraction (Pfe)mentioning

confidence: 99%

Sample Preparation in the Analysis of Pesticides Residue in Food by Chromatographic Techniques

Tan¹,

Chai²

2011

Pesticides - Strategies for Pesticides Analysis

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“…A otimização das etapas envolvidas no preparo da mesma é essencial para reduzir o tempo e as fontes de erro relacionadas ao procedimento. 10 Dentre as técnicas mais utilizadas para a extração de agrotóxicos em alimentos, podem ser citadas a extração acelerada por solvente, 11 extração líquido-líquido, 12 extração por ultrassom, 13 extração com fluido supercrítico 14,15 e a extração por dispersão da matriz em fase sólida. [16][17][18][19][20][21][22][23] Nos últimos anos, técnicas e métodos de preparo de amostra baseados na minimização do uso de solventes orgânicos para a extração de agrotóxicos foram desenvolvidos como, por exemplo, o método QuEChERS (Quick, Easy, Cheap, Effective, Ruged and Safe), o qual tem sido largamente empregado para determinação de agrotóxicos em matrizes complexas.…”

Section: Introductionunclassified

Otimização e validação de método empregando quechers modificado e lc-esi-ms/ms para determinação de agrotóxicos em cebola

et al. 2011

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. An evaluation of the pesticides extraction from onion using a modern sample preparation method (QuEChERS) and determination by liquid chromatography tandem mass spectrometry was carried out. All the calibration curves showed r>0.99. The recoveries ranged between 61.8 and 120.0% with relative standard deviation lower than 20% for all compounds. Due to the occurrence of matrix effect, the quantification was performed using matrix-matched calibration. The limits of quantification of the method were between 0.0005 and 0.05 mg kg -1 . The method shows the advantages of not require the clean-up step and consume low volume of organic solvents, decreasing time, costs and residues.

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Evaluation of analytical methods for determining pesticides in baby foods and adult duplicate-diet samples

Cited by 52 publications

References 3 publications

Multiresidue determination of pesticides in carrots using pressurized liquid extraction and gas chromatography with mass spectrometry detector

Multiresidue determination of pesticides in carrots using pressurized liquid extraction and gas chromatography with mass spectrometry detector

Sample Preparation in the Analysis of Pesticides Residue in Food by Chromatographic Techniques

Otimização e validação de método empregando quechers modificado e lc-esi-ms/ms para determinação de agrotóxicos em cebola

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