Evaluation of an anal sac adenocarcinoma tumor in a Spitz dog

Javanbakht, Javad; Tavassoli, Abbas; Sabbagh, Atefeh; Hassan, Mehdy Aghamohammmad; Samakkhah, Shohreh Alian; Shafiee, Radmehr; Lakzian, Ali; Ghalee, Vahideh Rahmani; Gharebagh, Sonia Shoja

doi:10.1016/s2221-1691(13)60027-1

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…However, we included three large regions (from North, Centre, and South of Italy, which represent almost 1/3 of the Italian child population) which are quite representative of the differences in socio-economic status found in Italy. Moreover, the fact that drug consumption is higher in southern Italy is reported in the annual report conducted by OsMed [33] ( Osservatorio sull’impiego dei medicinali ) in the general population, thus it is very likely that this trend is maintained in children.…”

Section: Discussionmentioning

confidence: 99%

Drug use profile in outpatient children and adolescents in different Italian regions

2013

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BackgroundLarge differences exist in the prevalence rate of drugs prescribed to children and adolescents between and within countries. The aim of this study was to evaluate child and adolescent drug prescription patterns in Italy in an extra-hospital setting at the regional and Local Health Unit (LHU) levels.MethodsData sources were three regional prescription databases. Data concerning the year 2008 were evaluated. A total of 3.3 million children and adolescents were included. Drug prevalence and prescription rates were evaluated at the regional and LHU levels. The correlation between mean latitude, average annual income, hospitalisation rate, number of paediatricians per 1,000 resident children, and prevalence rate was evaluated by LHU using a linear multiple regression analysis.ResultsLarge differences were found across Italian regions and LHUs. The mean prevalence rate was 56.4% (95% CI 56.3-56.5%; 51.2-65.4% among regions) and, at the LHU level, ranged from 43.1% to 70.0% (higher in the South). A total of 878 drugs were prescribed, 175 of which were shared by all LHUs. Amoxicillin clavulanate was the most used drug in all regions and in 31 of 33 LHUs. Amoxicillin was the drug with the highest variability in use between LHUs (9.1-52.1% of treated children). An inverse correlation was found between prevalence rate and both latitude (p < 0.0001) and average annual income (p = 0.0002).ConclusionsThe use of drugs in children and adolescents is higher in southern Italy and is inversely related to latitude and average annual income. More efforts should be devoted to informing physicians, patients and policy makers in order to plan effective initiatives to improve the situation.

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Section: Discussionmentioning

confidence: 99%

Drug use profile in outpatient children and adolescents in different Italian regions

2013

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System Biology Research to Advance the Understanding of Canine Cancer

Batan,

Kaur,

Rawal

et al. 2024

Sustainable Agriculture Reviews

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RETRACTED ARTICLE: Cyto-histopathological and outcome features of the prepuce squamous cell carcinoma of a mixed breed dog

et al. 2014

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BackgroundSquamous cell carcinomas (SCCs) are uncommon, high-grade tumors, predominantly composed of round cells in the prepuce. The aim of this study is to better define the clinicopathologic features of this neoplasm.Case reportWe conducted cyto-histopathologic analysis on the manifestations of the prepuce SCC by H & E staining in a terrier mix dog. Grossly, tumor was large, multiple erythematous patch, and ulcerated masses frequently affecting the prepuce and deeply invading to distal prepuce out from the ventro-lateral of penis and the tumor covered by a necrotic discharge. Cytological evaluation of fine-needle aspirates from the cutaneous mass from the prepuce comprised of round nuclei, coarse chromatin pattern, distinct nucleoli and nuclear pleomorphism. Furthermore, the neoplastic cells were pleomorphic, round to caudate in shape, exhibiting prominent anisokaryosis and anisocytosis with rare mitotic features. Microscopically, the lesions were predominantly composed of atypical round cells disposed in interlacing fascicles. Frequent findings include keratin formation, horn pearls, mitoses and cellular atypia. The cells showed distinct borders, ranged from polygonal to round or elongate and had moderate amounts of eosinophilic cytoplasm.ConclusionThe histopathologic features coupled with the cytopathology findings led to a diagnosis of squamous cell carcinoma. To the authors’ knowledge, this is the first time that multiple erythematous plaques have undergone malignant transformation in a terrier mix dog.Virtual SlidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/5748771971272873

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Evaluation of an anal sac adenocarcinoma tumor in a Spitz dog

Cited by 3 publications

References 18 publications

Drug use profile in outpatient children and adolescents in different Italian regions

Drug use profile in outpatient children and adolescents in different Italian regions

System Biology Research to Advance the Understanding of Canine Cancer

RETRACTED ARTICLE: Cyto-histopathological and outcome features of the prepuce squamous cell carcinoma of a mixed breed dog

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