Evaluation of agreement between intraocular pressure measurements using Goldmann applanation tonometry and Goldmann correlated intraocular pressure by Reichert's ocular response analyser

Abstract

Purpose To compare agreement of intraocular pressure (IOP) measurements using Goldmann applanation tonometry (GAT) and Goldmann correlated intraocular pressure generated (IOPg) by the Reichert ocular response analyser (ORA). Methods Consecutive patients presenting for glaucoma evaluation underwent ORA assessment followed by examination including GAT. For each ORA assessment, measurements were taken until a waveform score (WS) of 6.5 was obtained or until five measurements were obtained per eye. The relationship between GAT and IOPg and the influence of the WS upon this relationship was evaluated. A Bland-Altman plot and linear regression were used to determine agreement between GAT and IOPg. Results A total of 518 eyes of 260 patients were included in the final analysis. Increasing WS was found to predict a smaller difference between GAT and IOPg (b ¼ À0.2, Pp0.001). Selecting the highest WS among ORA assessments of each eye, WS continued to predict concordance between GAT and IOPg (b ¼ À0.2, P ¼ 0.006). The mean IOP difference between methods was 0.1 mm Hg (±0.3), which was found to be statistically insignificant (P ¼ 0.391). This relationship between GAT and IOPg was successfully validated using a second distinct data set of 100 eyes. GAT and IOPg measurements varied by 2 mm Hg or less in 53.9% of eyes and 5 mm Hg or less in 92.3% of eyes. Conclusion In clinical practice IOPg is strongly related to GAT. Although higher WS is indicative of greater IOPg/GAT concordance, its influence is minimal. This study does not support the use of a specific WS cutoff to determine quality of an IOPg measurement.

Outcomes of phacoemulsification and intraocular lens implantation in microphthalmos and nanophthalmos

“…Another limitation is that we measured IOP using the Ocular Response Analyzer in the majority of cases rather than by GAT, which is the gold standard technique for measuring IOP. Previous studies have shown there is good agreement between GAT and Ocular Response Analyzer Goldmann-correlated IOP 35 and repeatability of Ocular Response Analyzer IOP measurements is comparable to that of GAT. 36 Therefore, we believe this is unlikely to be of clinical significance.…”

Spectral domain optical coherence tomography imaging of the aqueous outflow structures in normal participants of the EPIC-Norfolk Eye Study

“…In the present study, IOP was measured using the ORA, despite the accepted gold standard technique for measuring IOP being Goldmann applanation tonometry (GAT). However, there is good agreement between GAT and ORA Goldmann-correlated IOP,23 and the repeatability of ORA IOP measurements is comparable to that of GAT 24. Relative to posterior segment OCT imaging, anterior segment OCT imaging and analysis is still in its infancy, and its features differ markedly between software versions and manufacturers.…”

Analyzing biomechanical parameters of the cornea with glaucoma severity in open-angle glaucoma

“…In addition to the impact of these parameters on the accuracy of Goldmann applanation tonometry (GAT) [5][6][7][8][9][10], it has been shown that these parameters are significantly reduced in glaucoma patients and appear to be a risk factor for glaucoma progression [11][12][13].…”