Evaluation of adjuvant psychological therapy in patients with testicular cancer: randomised controlled trial

Abstract

Objective: To determine the efficacy of adjuvant psychological therapy in patients with testicular cancer and to compare the characteristics and psychosocial outcomes of men who agreed to participate with those who declined to participate in a randomised trial of psychological intervention.

Selection of Patients may Limit the Generalizability of Results from Cancer Trials

“…The pretreatment characteristics of randomized and excluded patients may differ substantially with respect to clinical variables that potentially affect outcome (29). Patients who are willing to be entered into clinical trials differ from those who refuse randomization (1,5,6,30), as con rmed by our study. However, for most trials, no records concerning non-included eligible and ineligible patients are kept (3), and assessments of the generalizability of trial results are thus not possible or at least limited.…”

“I wish I’d told them”: A qualitative study examining the unmet psychosexual needs of prostate cancer patients during follow-up after treatment

“…This raises questions about whether there might be improvements needed to existing psychosexual services and how best to facilitate 4 men's access to health care if they experience problems [22,23]. Empirical evidence supports a popular belief that men encounter difficulties disclosing psychological difficulties during consultations [8,[24][25][26].…”

The effectiveness of treatment for depression/depressive symptoms in adults with cancer: a systematic review

“…The proportion of female participants ranged from between 41 to 100%. Eight studies were multicentre trials (McArdle et al, 1996;Classen et al, 2001;Goodwin et al, 2001;McLachlan et al, 2001;Petersen and Quinlivan, 2002;Rawl et al, 2002;Given et al, 2004;Weber et al, 2004) and 10 were single-centre trials (Burton et al, 1995;Evans and Connis, 1995;Marchioro et al, 1996;Moynihan et al, 1998;Edelman et al, 1999;Fukui et al, 2000;Sandgren et al, 2000;Antoni et al, 2001;Winzelberg et al, 2003;Kuijer et al, 2004).…”

“…Studies were conducted in Europe (n ¼ 5) (Burton et al, 1995;Marchioro et al, 1996;McArdle et al, 1996;Moynihan et al, 1998;Kuijer et al, 2004), the United States of America (n ¼ 8) (Evans and Connis, 1995;Sandgren et al, 2000;Antoni et al, 2001;Classen et al, 2001;Rawl et al, 2002;Winzelberg et al, 2003;Given et al, 2004;Weber et al, 2004) Canada (n ¼ 1) (Goodwin et al, 2001), Australia (n ¼ 3) (Edelman et al, 1999;McLachlan et al, 2001;Petersen and Quinlivan, 2002) and Japan (n ¼ 1) (Fukui et al, 2000). The mean sample size in the intervention and control group was 61 patients (range 15 -296) and 52 patients (range 15 -154), respectively.…”