Evaluation of Acid Resistance of Demineralized Dentin after Silver Diamine Fluoride and Potassium Iodide Treatment

Abstract

This study investigated the effects of silver diamine fluoride (SDF) and potassium iodide (KI) treatments on the acid resistance of dentin exposed to secondary caries. Sixteen bovine dentin specimens with artificially induced caries were assigned to the following four groups: untreated negative control, untreated positive control, SDF-treated (SDF), and SDF and KI-treated (SDFKI). Multispecies cariogenic biofilms containing <i>Streptococcus mutans</i>, <i>Lactobacillus casei</i>, and <i>Candida albicans</i> were cultured on the specimens for 28 days, except for the negative control group. Specimens from the negative control group were stored in phosphate-buffered saline for that period. After a cariogenic biofilm challenge, the degree of demineralization was evaluated using micro-computed tomography (micro-CT). As a result of data analysis using micro-CT, the demineralization depths of the negative control, positive control, SDF, and SDFKI groups were 149.0 ± 7 μm, 392.0 ± 11 μm, 206.0 ± 20 μm, and 230.0 ± 31 μm, respectively. The degree of demineralization was significantly reduced in the SDF and SDFKI groups compared with that in the untreated positive control group. There were no significant differences between the SDF and SDFKI groups. This study confirmed that SDF and SDFKI treatments increase the acid resistance of dentin to secondary caries. KI did not significantly affect the cariesarresting effect of the SDF.

Comparing cytocompatibility of two fluoride-containing solutions and two resin-based restorative materials—a pilot study

“…The ease of use is useful in treating large numbers of patients as a treatment modality for the prevention of caries ( 2 ). Various formulations of SDF have been assessed in the literature for caries remineralization, and the subsequent acid resistance of treated teeth ( 3 ) improved changes in the surface’s micro-hardness ( 4 , 5 ); the management of carious lesions as a result of molar incisor hypomineralization have been recorded ( 6 ). It has been realized that teeth usually treated with various SDF products have large active cavitated carious lesions, with the tooth very well at the end of its life span.…”

Managing Short Root Anomalies in Pediatric Cancer Survivors: Utilizing Resin Wire Splints and Miniscrews for Skeletal Anchorage

“…Treatment strategies for this malignancy include chemotherapy, radiation therapy (RT), hematopoietic stem cell transplantation (HSCT), and immunotherapy [4]. Meanwhile, dental developmental disturbances caused by these treatments include microdontia, short roots, root shunting, delayed or arrested dental development, enamel hypoplasia, abnormal crown size, and multiple tooth agenesis [5][6][7]. A previous study reported that the incidence of hypodontia and microdontia was higher in cancer survivors who received anticancer treatment before the age of 4 years [8].…”