Evaluation of a Portable Urinary pH Meter and Reagent Strips

Coninck, Vincent De; Keller, Etienne Xavier; Rodríguez-Monsalve, María; Doizi, Steeve; Audouin, Marie; Haymann, Jean‐Philippe; Traxer, Olivier

doi:10.1089/end.2018.0202

Cited by 16 publications

(9 citation statements)

References 17 publications

(12 reference statements)

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“…For some kinds of stones, the value of the urine pH is an important indicator of treatment success [93] and tracking this through each day using a dipstick has been recommended for cystinuric patients [1]. New devices that can provide more accurate measurement of urine pH by the patient at home are becoming commercially available [94,95]. Potentially such devices could also provide other measures of urine composition.…”

Section: Q10 Are There Any Specific Tests Available That Patients Camentioning

confidence: 99%

Urine and stone analysis for the investigation of the renal stone former: a consensus conference

et al. 2020

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The Consensus Group deliberated on a number of questions concerning urine and stone analysis over a period of months, and then met to develop consensus. The Group concluded that analyses of urine and stones should be routine in the diagnosis and treatment of urinary stone diseases. At present, the 24-h urine is the most useful type of urine collection, and accepted methods for analysis are described. Patient education is also important for obtaining a proper urine sample. Graphical methods for reporting urine analysis results can be helpful both for the physician and for educating the patient as to proper dietary changes that could be beneficial. Proper analysis of stones is also essential for diagnosis and management of patients. The Consensus Group also agreed that research has shown that evaluation of urinary crystals could be very valuable, but the Group also recognizes that existing methods for assessment of crystalluria do not allow this to be part of stone treatment in many places.

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Section: Q10 Are There Any Specific Tests Available That Patients Camentioning

confidence: 99%

Urine and stone analysis for the investigation of the renal stone former: a consensus conference

et al. 2020

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“…A urine pH of 8.5 or 9.0 is indicative of urea-splitting organisms [ 18 ]. In a previous study, a portable electronic pH meter was found to provide more accurate results than commonly used dipsticks or test strips [ 19 ]. In comparison, our UTI testing reagents were based on colorimetric analysis and demonstrated considerable specificity, agreement, PPV, and NPV, without electrically powered or complicated machine readers.…”

Section: Discussionmentioning

confidence: 99%

Urinalysis Using a Diaper-Based Testing Device

Sung

Liu²,

Yang

et al. 2020

Biosensors

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Urinary tract infections (UTI), one of the most common bacterial infections, annually affect 150 million people worldwide. Infants and the elderly are likely to have missed or delayed diagnosis of UTI due to difficulty clearly describing their symptoms. A rapid screening method for UTI is a critical and urgent need for these populations. The aim of our study is to develop a diaper-based testing device to assay urine biomarkers including pH, leukocyte, and nitrite level. This all-in-one device assists in urine collection and testing using a colorimetric approach to provide easily read visual results on the outside surface of a test strip-integrated diaper. In this study, we tested samples from 46 patients using testing strips and examined the results from 7 patients recruited to validate the strip-integrated diaper. In conclusion, this new diaper-based testing device is easy to use, rapid, and inexpensive, all of which imbue it with tremendous potential for development into a commercially viable UTI screening system.

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“…On the other hand, the pH meter is a medical device, which has been validated with patients [20,21], designed for urine pH self-monitoring, enabling patients to easily control urine pH on their own and its applicability may be extended to other urological pathologies where urinary pH plays an important role, such as acid-base imbalance diseases, urinary tract infections, cystitis, painful bladder syndrome or stent encrustation [22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Reduction of ureteral stent encrustation by modulating the urine pH and inhibiting the crystal film with a new oral composition: a multicenter, placebo controlled, double blind, randomized clinical trial

et al. 2020

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Background: Encrustation of ureteral double J stents is a common complication that may affect its removal. The aim of the proposed study is to evaluate the efficacy and safety of a new oral composition to prevent double J stent encrustation in indwelling times up to 8 weeks. Methods: A double-blinded, multicenter, placebo-controlled trial was conducted with 105 patients with indwelling double J stents enrolled across 9 public hospitals in Spain. The patients were randomly assigned (1:1) into intervention (53 patients) or placebo (52 patients) groups for 3 to 8 weeks and both groups self-monitored daily their morning urine pH levels. The primary outcome of analysis was the degree of stent ends encrustation, defined by a 4-point score (0none; 3global encrustation) using macroscopic and electron microscopy analysis of crystals, after 3 to 8-w indwelling period. Score was exponentially transformed according to calcium levels. Secondary endpoints included urine pH decrease, stent removal, and incidence of adverse events. Results: The intervention group benefits from a lower global encrustation rate of stent ends than placebo group (1% vs 8.2%; p < 0.018). Mean encrustation score was 85.12 (274.5) in the placebo group and 18.91 (102.27) in the intervention group (p < 0.025). Considering the secondary end points, treated patients reported greater urine pH decreases (p = 0.002). No differences in the incidence of adverse events were identified between the groups. Conclusions: Our data suggest that the use of this new oral composition is beneficial in the context of ureteral double J indwelling by decreasing mean, as well as global encrustation.

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Evaluation of a Portable Urinary pH Meter and Reagent Strips

Abstract: Findings of this study support that the portable electronic pH meter is a reliable pH measuring device. It appears to be more accurate compared to reagent strips readings.

Cited by 16 publications

References 17 publications

Urine and stone analysis for the investigation of the renal stone former: a consensus conference

Urine and stone analysis for the investigation of the renal stone former: a consensus conference

Urinalysis Using a Diaper-Based Testing Device

Reduction of ureteral stent encrustation by modulating the urine pH and inhibiting the crystal film with a new oral composition: a multicenter, placebo controlled, double blind, randomized clinical trial

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