Urine and stone analysis for the investigation of the renal stone former: a consensus conference

Williams, James C.; Gambaro, Giovanni; Rodgers, Allen L.; Asplin, John R.; Bonny, Olivier; Costa-Bauzà, Antònia; Ferraro, Pietro Manuel; Fogazzi, Giovanni B.; Fuster, Daniel; Goldfarb, David S.; Gráses, F.; Heilberg, Ita Pfeferman; Kok, Dirk J.; Letavernier, Emmanuel; Lippi, Giuseppe; Marangella, Martino; Nouvenne, Antonio; Petrarulo, Michele; Siener, Roswitha; Tiselius, H.-G.; Traxer, Olivier; Trinchieri, Alberto; Croppi, Emanuele; Robertson, William

doi:10.1007/s00240-020-01217-3

Cited by 49 publications

(51 citation statements)

References 119 publications

(153 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The daily fluid intake through beverages was 1.5 L on the WD and 2.5 L on the MD and VD. Dietary sodium intake was assessed by urinary excretion [20][21][22]. The composition of each standardized diet was estimated using PRODI version 5.3 (WVG, Stuttgart, Germany).…”

Section: Methodsmentioning

confidence: 99%

The Impact of Diet on Urinary Risk Factors for Cystine Stone Formation

Siener

Bitterlich²,

Birwé

et al. 2021

Nutrients

Self Cite

View full text Add to dashboard Cite

Despite the importance of dietary management of cystinuria, data on the contribution of diet to urinary risk factors for cystine stone formation are limited. Studies on the physiological effects of diet on urinary cystine and cysteine excretion are lacking. Accordingly, 10 healthy men received three standardized diets for a period of five days each and collected daily 24 h urine. The Western-type diet (WD; 95 g/day protein) corresponded to usual dietary habits, whereas the mixed diet (MD; 65 g/day protein) and lacto-ovo-vegetarian diet (VD; 65 g/day protein) were calculated according to dietary reference intakes. With intake of the VD, urinary cystine and cysteine excretion decreased by 22 and 15%, respectively, compared to the WD, although the differences were not statistically significant. Urine pH was significantly highest on the VD. Regression analysis showed that urinary phosphate was significantly associated with cystine excretion, while urinary sulfate was a predictor of cysteine excretion. Neither urinary cystine nor cysteine excretion was affected by dietary sodium intake. A lacto-ovo-vegetarian diet is particularly suitable for the dietary treatment of cystinuria, since the additional alkali load may reduce the amount of required alkalizing agents.

show abstract

Section: Methodsmentioning

confidence: 99%

The Impact of Diet on Urinary Risk Factors for Cystine Stone Formation

Siener

Bitterlich²,

Birwé

et al. 2021

Nutrients

Self Cite

View full text Add to dashboard Cite

show abstract

“…The path model, presented in Fig. 1, was developed by review the articles (12), textbooks (4) and the consensus of experts who specialize in various aspects of kidney stone prevention (14).…”

Section: Methodsmentioning

confidence: 99%

A Path Analysis To Investigate The Interaction Between Serum, Urinary And Demographic Factors Influencing Urine Calcium In Kidney Stone Formers

Taheri

Tavasoli

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: Hypercalciuria is one of the most important urinary risk factors in kidney stone formers. This study aimed to delineate the interaction of some demographic, serum, and urinary risk factors influencing 24-hour urinary (24-U) calcium excretion.Methods: This study was secondary data analysis, using data from 593 kidney stone patients referred to the Labbafinejad kidney stone prevention clinic from March 2015 to May 2019. The study considered serum, urinary and demographic factors that interact to influence 24-U calcium using path analysis.Results: The results showed that age and weight had an indirect effect on 24-U calcium. Among serum variables, PTH and creatinine had a significant direct effect on 24-U calcium. In comparison, 25-hydroxy vitamin D (25(OH)D) and phosphorus appeared to influence 24-U calcium through serum parathormone. Regarding 24-U metabolites, 24-U sodium, 24-U Urea, and 24-U citrate had a significant direct effect on 24-U calcium. Moreover, 24-U creatinine has a significant direct and indirect effect on 24-U calcium through 24-U citrate and 24-U Urea as mediating variables. 24-U citrate had the most effect on 24-U calcium, following 24-U creatinine, 24-U Urea, 24-U sodium, serum creatinine, and weight.Conclusion: Except for serum calcium, all other predictors had direct and/or indirect effects on 24-U calcium. Serum 25(OH)D had a negligible indirect effect on 24-U calcium. Controlling dietary intake of protein and sodium and bodyweight seems very important in kidney stone formers with hypercalciuria.

show abstract

“…A reliable stone analysis is an essential precondition for specific treatment regimens, because urinary risk factors for stone formation vary with the type of stone [10,11]. Moreover, a thorough metabolic evaluation of the stone patient is required, including detailed medical history, dietary assessment as well as blood and urine analysis [11][12][13][14][15][16][17]. To reduce the risk of recurrent stone formation, targeted dietary treatment should be individually adjusted to the metabolic risk profile of each patient.…”

Section: Introductionmentioning

confidence: 99%

Nutrition and Kidney Stone Disease

Siener

2021

Nutrients

Self Cite

118

View full text Add to dashboard Cite

The prevalence of kidney stone disease is increasing worldwide. The recurrence rate of urinary stones is estimated to be up to 50%. Nephrolithiasis is associated with increased risk of chronic and end stage kidney disease. Diet composition is considered to play a crucial role in urinary stone formation. There is strong evidence that an inadequate fluid intake is the major dietary risk factor for urolithiasis. While the benefit of high fluid intake has been confirmed, the effect of different beverages, such as tap water, mineral water, fruit juices, soft drinks, tea and coffee, are debated. Other nutritional factors, including dietary protein, carbohydrates, oxalate, calcium and sodium chloride can also modulate the urinary risk profile and contribute to the risk of kidney stone formation. The assessment of nutritional risk factors is an essential component in the specific dietary therapy of kidney stone patients. An appropriate dietary intervention can contribute to the effective prevention of recurrent stones and reduce the burden of invasive surgical procedures for the treatment of urinary stone disease. This narrative review has intended to provide a comprehensive and updated overview on the role of nutrition and diet in kidney stone disease.

show abstract

Urine and stone analysis for the investigation of the renal stone former: a consensus conference

Cited by 49 publications

References 119 publications

The Impact of Diet on Urinary Risk Factors for Cystine Stone Formation

The Impact of Diet on Urinary Risk Factors for Cystine Stone Formation

A Path Analysis To Investigate The Interaction Between Serum, Urinary And Demographic Factors Influencing Urine Calcium In Kidney Stone Formers

Nutrition and Kidney Stone Disease

Contact Info

Product

Resources

About