Evaluation of a<i>Bacillus</i>direct-fed microbial candidate on digesta viscosity, bacterial translocation, microbiota composition and bone mineralisation in broiler chickens fed on a rye-based diet

Latorre, Juan D.; Hernández-Velasco, Xóchitl; Bielke, Lisa R.; Vicente, J. L.; Wolfenden, R. E.; Menconi, A.; Hargis, Billy M.; Téllez, G.

doi:10.1080/00071668.2015.1101053

Cited by 66 publications

(61 citation statements)

References 43 publications

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“…Broilers fed Bacillus ‐supplemented diets exhibit reduced digesta viscosity caused by soluble nonstarch polysaccharide, which can affect nutrient availability and absorption (Latorre et al . ). In addition to promoting the growth performance and health of poultry, feed with added Bacillus also improves the quality of meat (e.g.…”

Section: Mode Of Action and Efficiency Of Bacillus In Terrestrial Andmentioning

confidence: 97%

“…Sen et al (2012) observed that administration of Bacillus causes histomorphological changes in the intestine of broilers, increasing villus height and villus height to crypt dept ratio, and thus improves the nutrient digestibility and absorption capacity of the small intestine. Broilers fed Bacillussupplemented diets exhibit reduced digesta viscosity caused by soluble nonstarch polysaccharide, which can affect nutrient availability and absorption (Latorre et al 2015). In addition to promoting the growth performance and health of poultry, feed with added Bacillus also improves the quality of meat (e.g.…”

Section: Poultrymentioning

confidence: 99%

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Bacillusprobiotics: an alternative to antibiotics for livestock production

2018

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SummaryThe use of probiotics as feed supplements in animal production has increased considerably over the last decade, particularly since the ban on antibiotic growth promoters in the livestock sector. Several Bacillus sp. are attractive for use as probiotic supplements in animal feed due to their ability to produce spores. Their heat stability and ability to survive the low pH of the gastric barrier represent an advantage over other probiotic micro-organisms. This review discusses important characteristics required for selection of Bacillus probiotic strains and summarizes the beneficial effect of Bacillus-based feed additives on animal production. Although the mechanism of action of Bacillus probiotics has not been fully elucidated, they are effective in improving the growth, survival and health status of terrestrial and aquatic livestock. Bacillus strains also have utility in bioremediation and can reduce nitrogenous waste, thereby improving environmental conditions and water quality. Finally, recent innovative approaches for using Bacillus spores in various applications are discussed.

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Section: Mode Of Action and Efficiency Of Bacillus In Terrestrial Andmentioning

confidence: 97%

Section: Poultrymentioning

confidence: 99%

Bacillusprobiotics: an alternative to antibiotics for livestock production

2018

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“…Previous results from our laboratory have demonstrated that in poultry, chemically induced disruption of TJs with DSS (10) increases transmucosal permeability as seen by elevated serum levels of FITC-d (11). On the other hand, recently, we have shown that dietary inclusion of a Bacillus -based direct-fed microbial ameliorated the adverse gut permeability inflammatory effects related to utilization of rye-based diets in turkeys and in broiler chickens (15, 16). We have previously shown that FITC-d can be used as a biomarker for intestinal barrier function (7–12).…”

Section: Introductionmentioning

confidence: 98%

Optimizing Fluorescein Isothiocyanate Dextran Measurement As a Biomarker in a 24-h Feed Restriction Model to Induce Gut Permeability in Broiler Chickens

et al. 2017

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Fluorescein isothiocyanate dextran (FITC-d) is a 3–5 kDa marker used to measure tight junction permeability. We have previously shown that intestinal barrier function can be adversely affected by stress, poorly digested diets, or feed restriction (FR), resulting in increased intestinal inflammation-associated permeability. However, further optimization adjustments of the current FITC-d methodology are possible to enhance precision and efficacy of results in future. The objective of the present study was to optimize our current model to obtain a larger difference between control and treated groups, by optimizing the FITC-d measurement as a biomarker in a 24-h FR model to induce gut permeability in broiler chickens. One in vitro and four in vivo independent experiments were conducted. The results of the present study suggest that by increasing the dose of FITC-d (8.32 versus 4.16 mg/kg); shortening the collection time of blood samples (1 versus 2.5 h); using a pool of non-FITC-d serum as a blank, compared to previously used PBS; adding a standard curve to set a limit of detection and modifying the software’s optimal sensitivity value, it was possible to obtain more consistent and reliable results.

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“…The increase of digesta transit induces higher bacteria proliferation, especially undesirable microbes such as Escherichia coli and Clostridium perfringens [46,47]. Moreover, diets with high NSP promote higher bacterial translocation from the gut to the blood system, due to the leaky gut [48,49] that can produce systemic infection and inflammation.…”

Section: Non-starch Polysaccharidesmentioning

confidence: 99%

Dietary Factors as Triggers of Low-Grade Chronic Intestinal Inflammation in Poultry

Pont¹,

Farnell²,

Farnell³

et al. 2020

Microorganisms

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Inflammation is the reaction of the immune system to an injury; it is aimed at the recovery and repair of damaged tissue. The inflammatory response can be beneficial to the animal since it will reestablish tissue homeostasis if well regulated. However, if it is not controlled, inflammation might lead to a chronic response with a subsequent loss of tissue function. The intestine is constantly exposed to a number of environmental triggers that stimulate inflammation and lead to a reduction in performance. The diet and dietary components constitute consistent inflammatory triggers in poultry. Dietary components, such as anti-nutritional compounds, oxidized lipids, mycotoxins, and excess of soluble fiber or protein, are all capable of inducing a low-grade inflammatory response in the intestine of broilers throughout a 5-week grow-out period. We hypothesized that dietary factor-induced chronic intestinal inflammation is a key driver of the lower performance and higher incidence of intestinal problems observed in poultry production. Therefore, this review was aimed at exploring feed-induced chronic inflammation in poultry, the constituents of the diet that might act as inflammatory triggers and the possible effects of chronic intestinal inflammation on the poultry industry.

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Evaluation of aBacillusdirect-fed microbial candidate on digesta viscosity, bacterial translocation, microbiota composition and bone mineralisation in broiler chickens fed on a rye-based diet

Cited by 66 publications

References 43 publications

Bacillusprobiotics: an alternative to antibiotics for livestock production

Bacillusprobiotics: an alternative to antibiotics for livestock production

Optimizing Fluorescein Isothiocyanate Dextran Measurement As a Biomarker in a 24-h Feed Restriction Model to Induce Gut Permeability in Broiler Chickens

Dietary Factors as Triggers of Low-Grade Chronic Intestinal Inflammation in Poultry

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