Evaluation of 28 balm and lemon balm (Melissa officinalis) accessions for content and composition of essential oil and content of rosmarinic acid

Kittler, Johannes; Krüger, Hans; Lohwasser, U.; Ulrich, Detlef; Zeiger, Bärbel; Schütze, Wolfgang; Böttcher, Ch.; Gudi, Gennadi; Kästner, Ute; Marthe, Frank

doi:10.1007/s10722-017-0568-3

Cited by 11 publications

(12 citation statements)

References 18 publications

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“…The determined yield revealed that the plant sample from western Romania is rich in essential oil. Moreover, the results match the scientific literature's values that report yields ranged between 0.01 and 0.45% (dry material) [44]. Higher yields have been recorded for M. officinalis from Brazil (0.97%) [45], Iran (1%) [46], and Spain (0.8%) [47].…”

Section: Moeo Chemical Compositionsupporting

confidence: 85%

“…Higher yields have been recorded for M. officinalis from Brazil (0.97%) [45], Iran (1%) [46], and Spain (0.8%) [47]. According to Kittler et al [44], the lemon balm EO content is strongly related to the biotic and abiotic conditions, different harvesting years, and genetic makeup of the genotypes.…”

Section: Moeo Chemical Compositionmentioning

confidence: 99%

“…However, caryophyllene, the second major compound of the analyzed oil, has been recorded in large amounts in subsp. officinalis from Sardinia (20-39%) [50] and Germany (1.17-18.64%) [44]. Another peculiarity of the analyzed oil is the low content of alpha-citral (2.06%), beta-citral (1.15%), and citronellal (0.27%), compared with other subsp.…”

Section: Moeo Chemical Compositionmentioning

confidence: 99%

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Chemical Composition, In Vitro and In Silico Antioxidant Potential of Melissa officinalis subsp. officinalis Essential Oil

et al. 2021

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The investigation aimed to study the in vitro and in silico antioxidant properties of Melissa officinalis subsp. officinalis essential oil (MOEO). The chemical composition of MOEO was determined using GC–MS analysis. Among 36 compounds identified in MOEO, the main were beta-cubebene (27.66%), beta-caryophyllene (27.41%), alpha-cadinene (4.72%), caryophyllene oxide (4.09%), and alpha-cadinol (4.07%), respectively. In vitro antioxidant properties of MOEO have been studied in 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging, and inhibition of β-carotene bleaching assays. The half-maximal inhibitory concentration (IC50) for the radical scavenging abilities of ABTS and DPPH were 1.225 ± 0.011 μg/mL and 14.015 ± 0.027 μg/mL, respectively, demonstrating good antioxidant activity. Moreover, MOEO exhibited a strong inhibitory effect (94.031 ± 0.082%) in the β-carotene bleaching assay by neutralizing hydroperoxides, responsible for the oxidation of highly unsaturated β-carotene. Furthermore, molecular docking showed that the MOEO components could exert an in vitro antioxidant activity through xanthine oxidoreductase inhibition. The most active structures are minor MOEO components (approximately 6%), among which the highest affinity for the target protein belongs to carvacrol.

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Section: Moeo Chemical Compositionsupporting

confidence: 85%

Section: Moeo Chemical Compositionmentioning

confidence: 99%

Section: Moeo Chemical Compositionmentioning

confidence: 99%

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Chemical Composition, In Vitro and In Silico Antioxidant Potential of Melissa officinalis subsp. officinalis Essential Oil

et al. 2021

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“…The evaluation results of 28 M. officinalis accessions which include 10 accessions of ct. germacrene D and 15 of ct. citral (Kittler et al 2018) should also be include in the selection of the core collection to reach the maximum of variability for characterized traits. Candidate accessions should be tested more intensive again.…”

Section: Discussionmentioning

confidence: 99%

“…In a set of 28 accessions Kittler et al (2018) describe beside diploid populations with lemon like scent also 12 tetraploid accessions. Of these tetraploid accessions ten had a soaplike scent and belong to a chemotype which had germacrene D as the main component of the essential oil.…”

Section: Introductionmentioning

confidence: 99%

Content and composition of essential oil and content of rosmarinic acid in lemon balm and balm genotypes (Melissa officinalis)

Kittler

Krüger

Ulrich

et al. 2018

Genet Resour Crop Evol

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Lemon balm (Melissa officinalis L.) is used since ancient times because of its sedative, spasmolytic and antiviral effects. Its therapeutic impact is due to the content of essential oil and rosmarinic acid. A set of 68 M. officinalis genotypes was evaluated for content and composition of essential oil and the content of rosmarinic acid. For all genotypes the level of ploidy was determined. The 68 genotypes were clone plants grown and evaluated for two years at Quedlinburg. For analysis of secondary metabolites distillation, gas chromatography and high performance liquid chromatography was used. The content of essential oil varied in this study in ranges from 0.03 to 0.33% for the second cut 2010 and 0.01-0.35% for the second cut 2011. The rosmarinic acid content ranged in the year 2010 from 3.67 to 7.55% and in the year 2011 from 4.92 to 8.07%. Via statistical analyses two chemotypes of essential oil were found: chemotype citral and chemotype bcaryophyllene oxide. Ploidy was determined for all genotypes and two cytotypes were found: diploid 2n = 2x = 32 (62 of 68 genotypes) and triploid 2n = 3x = 48 (6 of 68 genotypes).

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Genetic structure and relationships among Melissa officinalis accessions using AFLP markers

Danaeipour

Fotokian

Talei

et al. 2019

Biocatalysis and Agricultural Biotechnology

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Evaluation of 28 balm and lemon balm (Melissa officinalis) accessions for content and composition of essential oil and content of rosmarinic acid

Cited by 11 publications

References 18 publications

Chemical Composition, In Vitro and In Silico Antioxidant Potential of Melissa officinalis subsp. officinalis Essential Oil

Chemical Composition, In Vitro and In Silico Antioxidant Potential of Melissa officinalis subsp. officinalis Essential Oil

Content and composition of essential oil and content of rosmarinic acid in lemon balm and balm genotypes (Melissa officinalis)

Genetic structure and relationships among Melissa officinalis accessions using AFLP markers

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