“…14,15 The PET measures the in vivo body distribution of imaging agents labeled with positron-emitting radionucleotides and has been extensively used in humans to characterize the heart with respect to properties such as perfusion, 16,17 metabolism,18,19 innervation,20,21 and cardiac function. 22,23 With the introduction of high-resolution small-animal PET, 24,25 in vivo molecular imaging of myocardial metabolism in small laboratory animals, mostly mice and rats, has become possible.…”