Évaluation endothéliale cornéenne des patients diabétiques après une phacoémulsification

Maadane, A.; Boutahar, H.; Bourakba, S.; Sekhsoukh, R.

doi:10.1016/j.jfo.2018.09.012

Cited by 9 publications

(8 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, after phacoemulsification, a decrease in the number of endothelial cells was noticed in each group individually, but comparatively, the cells loss in the diabetic group was statistically more significant than in the non-diabetic group (a mean endothelial cell loss of 472.7 ± 369.1 versus 165.7 ± 214.6). Similar to our study, the research conducted by Yang et al [ 34 ] and Maadane et al [ 35 ] reported significant corneal endothelial cell loss after cataract surgery, both in the diabetic group and the control group. Sharma et al [ 36 ] also obtained similar results: the CD was lower in the diabetic patients than in the control group, respectively, 2550 ± 326 versus 2634 ± 256, but no difference was noted in the mean pachymetry or hexagonality.…”

Section: Discussionsupporting

confidence: 92%

Evaluation of the Corneal Endothelium Following Cataract Surgery in Diabetic and Non-Diabetic Patients

et al. 2023

View full text Add to dashboard Cite

The aim of this study was to evaluate the influence of phacoemulsification cataract surgery on the state of the corneal endothelium in diabetic versus non-diabetic patients. We compared the corneal cell morphology in 48 diabetics with good glycemic control and 72 non-diabetic patients before and after uneventful phacoemulsification. Corneal cell density, central corneal thickness, and hexagonality were measured preoperatively and post-surgery (at 1 and 4 weeks) by specular microscopy. The effect of age, gender, axial length, and anterior chamber depth on the parameters of the corneal endothelium were evaluated. We noticed a drop in the endothelial density in both groups postoperatively: a mean endothelial cell loss of 472.7 ± 369.1 in the diabetic group was recorded versus 165.7 ± 214.6 mean loss in the non-diabetic group after the first week. A significant increase in central corneal thickness was also noticed in both groups one week after phacoemulsification, but no statistical significance after 4 weeks in the diabetic group. In terms of cell hexagonality, statistically significant differences were noticed after 4 weeks in both groups. Overall, a significant difference between diabetic and non-diabetic population was noticed in terms of corneal endothelial cell loss after uneventful phacoemulsification cataract surgery. Routine specular microscopy and HbA1c evaluation is recommended before cataract surgery, while intraoperative precautions and high monitorisation in terms of pacho power intensity and ultrasound energy, along with a proper application of the dispersive viscoelastic substances are essential to reduce the risk of endothelial damage.

show abstract

Section: Discussionsupporting

confidence: 92%

Evaluation of the Corneal Endothelium Following Cataract Surgery in Diabetic and Non-Diabetic Patients

et al. 2023

View full text Add to dashboard Cite

show abstract

“…The ECD loss after cataract surgery reported in the DM group ranged from 5.95% to 29.07% in the literature (Table 3). [6][7][8][9][10][11][12][13][14][15][16][17] Endothelial cell loss varies from study to study due to varying surgical techniques, different patient populations, and time points of corneal endothelial cell evaluation after surgery. Most previous studies reported that ECD loss in patients with diabetes is statistically significant after surgery compared to control groups.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have shown that diabetic patients may be more susceptible to corneal complications before and after intraocular surgery [6–26] . According to the reported results, after cataract surgery, the loss of ECD in diabetic patients was 5.95% to 29.07%, compared to 0.88% to 18.18% in healthy individuals [6–17] . Previous studies have shown varying results on whether diabetic patients have an increased risk of ECD loss after phacoemulsification.…”

Section: Introductionmentioning

confidence: 99%

“…According to the reported results, after cataract surgery, the loss of ECD in diabetic patients was 5.95% to 29.07%, compared to 0.88% to 18.18% in healthy individuals. [6][7][8][9][10][11][12][13][14][15][16][17] Previous studies have shown varying results on whether diabetic patients have an increased risk of ECD loss after phacoemulsification. In addition, most of the studies evaluated short-term changes within 3 months, and there are few papers analyzing the effect of diabetic duration and results from serum laboratory tests such as HbA1c and blood urea nitrogen (BUN) on ECD loss.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of corneal endothelial cell changes after phacoemulsification between type 2 diabetic and nondiabetic patients

Joo

Kim

2021

Medicine

View full text Add to dashboard Cite

The aim of this study is to compare the endothelial cell density (ECD) and morphology between diabetic mellitus (DM) and nondiabetic patients at 1 year after phacoemulsification in operated eyes and nonoperated eyes. Evaluation was performed in 28 patients (56 eyes) with type 2 diabetes and 37 patients (74 eyes) without diabetes who underwent 1-year interval cataract surgery. Using a noncontact specular microscope and Scheimpflug rotating camera, corneal parameters were analyzed before and 1 year after surgery. Subgroups analysis was performed based on a disease duration 10 years and HbA1c concentration 7% and Pearson correlation analysis was performed. The mean change in ECD at 1 year after surgery was 13.28% in the DM group and 11.40% in the control group. In the fellow nonoperated eyes, the mean change was 4.47% and 3.63% in the DM and control groups, respectively. There was no significant difference in postoperative ECD, coefficient of variance, hexagonality, and central corneal thickness between 2 groups. In the subgroup analysis, the long disease duration DM group (≥10 years) had a significantly greater ECD loss than the control and short disease duration DM groups (<10 years). Blood urea nitrogen (BUN) showed a significant correlation with postoperative ECD change ( r = −0.474, P = .011). The diabetic group with a longer disease duration showed significantly greater ECD decrease compared to the nondiabetic group and BUN correlated with ECD changes after phacoemulsification. Postoperative ECD loss may be high if the disease duration is long or if the BUN level is high.

show abstract

“…Our results showed that the degree of morphological variation of CECs in diabetic patients was largest at 1 month postoperatively, which was significantly higher than that in non-diabetic patients, and subsequently, the degree of morphological variation of CECs gradually decreased. The corneal morphology of diabetic patients was more unstable in the early postoperative stage, indicating that the endothelial cells of diabetic patients have a weaker repair ability upon damage, and the repair process takes longer [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

Meta-analysis of corneal endothelial changes after phacoemulsification in diabetic and non-diabetic patients

et al. 2023

View full text Add to dashboard Cite

Background Currently, there is still controversy about the differential changes in corneal endothelium function and morphology after phacoemulsification between Diabetes Mellitus (DM) and non-Diabetes Mellitus (non-DM) patients. In this study, we aimed to evaluate the influence of phacoemulsification on the corneal endothelium in DM and non-DM patients. Methods Databases of PubMed, Embase, Web of Science, and the Cochrane Library were searched for studies published between January 1, 2011 and December 25, 2021. The weighted mean difference and 95% confidence interval were used to estimate the outcomes of statistical analyses performed. Results Thirteen studies involving 1744 eyes were included in this meta-analysis. No significant difference was observed in the central corneal thickness (CCT), endothelial cell density (ECD), coefficients of variation (CV), or hexagonal cell percentage (HCP) between the DM and non-DM groups (CCT: P = 0.91; ECD: P = 0.07; CV: P = 0.06; HCP: P = 0.09) preoperatively. The CCT was significantly thicker in the DM group at 1 month (P = 0.003) and 3 months (P = 0.0009) postoperatively, and there was no significant difference at 6 months postoperatively (P = 0.26) than non-DM group. The CV was significantly higher and HCP was significantly lower in the DM group at 1 month (CV:P < 0.0001, HCP: P = 0.002), with no significant difference at 3 months (CV: P = 0.09, HCP: P = 0.36) and 6 months (CV: P = 0.32, HCP: P = 0.36) postoperatively than non-DM group. DM patients had lower ECD than non-DM patients at all postoperative time points (1 month, 3 months: P < 0.00001, 6 months: P < 0.0001). Conclusions The influence of phacoemulsification on corneal endothelial damage is greater in diabetic patients. Moreover, the recovery of corneal endothelial function and morphology is delayed in these patients. Clinicians should be more attentive to the corneal health of DM patients when considering phacoemulsification.

show abstract

Évaluation endothéliale cornéenne des patients diabétiques après une phacoémulsification

Cited by 9 publications

References 14 publications

Evaluation of the Corneal Endothelium Following Cataract Surgery in Diabetic and Non-Diabetic Patients

Evaluation of the Corneal Endothelium Following Cataract Surgery in Diabetic and Non-Diabetic Patients

Comparison of corneal endothelial cell changes after phacoemulsification between type 2 diabetic and nondiabetic patients

Meta-analysis of corneal endothelial changes after phacoemulsification in diabetic and non-diabetic patients

Contact Info

Product

Resources

About