Evaluating the informative power of Y-STRs: a comparative study using European and new African haplotype data

Alves, Cı́ntia; Gusmão, Leonor; Barbosa, Joselina; Amorim, António

doi:10.1016/s0379-0738(03)00127-0

Cited by 55 publications

(37 citation statements)

References 13 publications

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“…the pairwise Rst genetic distances analysis obtained among male population sample from cabo Verde and others from Iberia and Africa sub-saharan, showed a similar significant differentiation from Iberian populations (0.13352<Rst<0.17027, p=0.00000) [9,10,11] and from Africa sub-saharan populations (0.13401<Rst<0.15268, p=0.00000) [12,13,14].…”

Section: Resultsmentioning

confidence: 53%

Paternal and maternal lineages in Cabo Verde archipelago population

Côrte-Real¹,

Gusmão²,

Anjos³

et al. 2010

Acta Medicinae Legalis Et Socialis

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A navegação consulta e descarregamento dos títulos inseridos nas Bibliotecas Digitais UC Digitalis, UC Pombalina e UC Impactum, pressupõem a aceitação plena e sem reservas dos Termos e Condições de Uso destas Bibliotecas Digitais, disponíveis em https://digitalis.uc.pt/pt-pt/termos.Conforme exposto nos referidos Termos e Condições de Uso, o descarregamento de títulos de acesso restrito requer uma licença válida de autorização devendo o utilizador aceder ao(s) documento(s) a partir de um endereço de IP da instituição detentora da supramencionada licença.Ao utilizador é apenas permitido o descarregamento para uso pessoal, pelo que o emprego do(s) título(s) descarregado(s) para outro fim, designadamente comercial, carece de autorização do respetivo autor ou editor da obra.Na medida em que todas as obras da UC Digitalis se encontram protegidas pelo Código do Direito de Autor e Direitos Conexos e demais legislação aplicável, toda a cópia, parcial ou total, deste documento, nos casos em que é legalmente admitida, deverá conter ou fazer-se acompanhar por este aviso. Paternal and maternal lineages in

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Section: Resultsmentioning

confidence: 53%

Paternal and maternal lineages in Cabo Verde archipelago population

Côrte-Real¹,

Gusmão²,

Anjos³

et al. 2010

Acta Medicinae Legalis Et Socialis

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“…Samples and DNA purification A total of 389 DNA samples from unrelated males (the numbers of individuals are given in parentheses) from Turkey (59), Iraq (64), Somalia (201) (all immigrants to Denmark) and 65 sub-Saharan Western Africans from Mali (38), Ghana (16), Mauritania (three), Guinea Conakry (two), Liberia (two), Cote d'Ivoire (one), Guinea -Bissau (one), Senegal (one) and Cameroon (one) (all immigrants to the Canary Islands) were typed in duplicates for 45 biallelic Y chromosome markers. Blood on FTA cards or Qiagen-purified DNA was used.…”

Section: Methodsmentioning

confidence: 99%

High frequencies of Y chromosome lineages characterized by E3b1, DYS19-11, DYS392-12 in Somali males

et al. 2005

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We genotyped 45 biallelic markers and 11 STR systems on the Y chromosome in 201 male Somalis. In addition, 65 sub-Saharan Western Africans, 59 Turks and 64 Iraqis were typed for the biallelic Y chromosome markers. In Somalis, 14 Y chromosome haplogroups were identified including E3b1 (77.6%) and K2 (10.4%). The haplogroup E3b1 with the rare DYS19-11 allele (also called the E3b1 cluster c) was found in 75.1% of male Somalis, and 70.6% of Somali Y chromosomes were E3b1, DYS19-11, DYS392-12, DYS437-14, DYS438-11 and DYS393-13. The haplotype diversity of eight Y-STRs ('minimal haplotype') was 0.9575 compared to an average of 0.9974 and 0.9996 in European and Asian populations. In sub-Saharan Western Africans, only four haplogroups were identified. The West African clade E3a was found in 89.2% of the samples and the haplogroup E3b1 was not observed. In Turks, 12 haplogroups were found including J2*(xJ2f2) (27.1%), R1b3*(xR1b3d, R1b3f) (20.3%), E3b3 and R1a1*(xR1a1b) (both 11.9%). In Iraqis, 12 haplogroups were identified including J2*(xJ2f2) (29.7%) and J*(xJ2) (26.6%). The data suggest that the male Somali population is a branch of the East African population -closely related to the Oromos in Ethiopia and North Kenya -with predominant E3b1 cluster c lineages that were introduced into the Somali population 4000 -5000 years ago, and that the Somali male population has approximately 15% Y chromosomes from Eurasia and approximately 5% from sub-Saharan Africa.

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“…Ychromosome short tandem repeats (Y-STRs), on the other hand, mutate rapidly and are more suitable for reconstructing the phylogeny of relatively recent demographic events as well as for forensic casework and paternity testing [2,[4][5][6]. Recently, Y-STR data have been increasingly used to investigate the evolution, migration, and genetic diversity of modern human populations [2,[6][7][8][9][10][11]. This interest in YSTRs as markers for ancestry and population studies have prompted the creation of a comprehensive worldwide Y-STR database called Y-Chromosome Haplotype Reference Database (YHRD, www.yhrd.org) for calculating haplotype frequencies, matching probabilities, and performing comparative population genetic analyses [12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Y-STR diversity in the Himalayas

et al. 2010

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Linguistic and ethnic diversity throughout the Himalayas suggests that this mountain range played an important role in shaping the genetic landscapes of the region. Previous Y-chromosome work revealed that the Himalayas acted as a biased bidirectional barrier to gene flow across the cordillera. In the present study, 17 Y-chromosomal short tandem repeat (Y-STR) loci included in the AmpFlSTR® Yfiler kit were analyzed in 344 unrelated males from three Nepalese populations (Tamang, Newar, and Kathmandu) and a general collection from Tibet. The latter displays the highest haplotype diversity (0.9990) followed by Kathmandu (0.9977), Newar (0.9570), and Tamang (0.9545). The overall haplotype diversity for the Himalayan populations at 17 Y-STR loci was 0.9973, and the corresponding values for the extended (11 loci) and minimal (nine loci) haplotypes were 0.9955 and 0.9942, respectively. No Y-STR profiles are shared across the four Himalayan collections at the 17-, 11-, and nine-locus resolutions considered, indicating a lack of recent gene flow among them. Phylogenetic analyses support our previous findings that Kathmandu, and to some extent Newar, received significant genetic influence from India while Tamang and Tibet exhibit limited or no gene flow from the subcontinent. A median-joining network of haplogroup O3a3c-M134 based on 15 Y-STR loci from our four Himalayan populations suggests either a male founder effect in Tamang, possibly from Tibet, or a recent bottleneck following their arrival south of the Himalayas from Tibet leading to their highly reduced Y single-nucleotide polymorphism and Y-STR diversity. The genetic uniqueness of the four Himalayan populations examined in this study merits the creation of separate databases for individual identification, parentage analysis, and population genetic studies.

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Evaluating the informative power of Y-STRs: a comparative study using European and new African haplotype data

Cited by 55 publications

References 13 publications

Paternal and maternal lineages in Cabo Verde archipelago population

Paternal and maternal lineages in Cabo Verde archipelago population

High frequencies of Y chromosome lineages characterized by E3b1, DYS19-11, DYS392-12 in Somali males

Y-STR diversity in the Himalayas

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