Evaluating initial spine trauma response: Injury time to trauma center in PA, USA

Surgical management of patients following traumatic spinal cord injury: Identifying barriers to early surgery in a specialized spinal cord injury center

“…Finally, whether patients were transferred from a CH located at a long distance from the SCI center by air or road transportation did not seem to affect the surgical delay, since 3 out of the 6 patients transferred by air transport had LS surgery, with delays ranging between 28 hours and 96 hours. This goes along the same lines as what was reported by Harrop et al, 19 where long delays from trauma to arrival at the trauma center were observed in patients transferred by helicopter transportation.…”

“…Nevertheless, patients started being managed by the SCI specialized team within less than 2.5 hours post-trauma, which was 6 hours faster than for patients transported to another CH. Our 2.5-hour delay was also well below what was observed by Harrop et al, 19 where patients sustaining a T-SCI were transported to a Level I or II hospital within 5.2 hours in Pennsylvania. Finally, whether patients were transferred from a CH located at a long distance from the SCI center by air or road transportation did not seem to affect the surgical delay, since 3 out of the 6 patients transferred by air transport had LS surgery, with delays ranging between 28 hours and 96 hours.…”

“…In our study, 64% of patients with T-SCI had ES while the remaining 36% had LS, with an average delay of nearly 46 hours. Based on the Canadian studies by Noonan et al 20 and Furlan et al, 19 we calculated the number of patients enrolled in our study that could have been operated within 24 hours, had our delays been the same as reported in those studies. We considered the time of transfer from the CH to the SCI center, the delay between the first medical assessment and surgical plan completion, and the delay waiting for the operating room, which were the three main predictors of having LS.…”

Epidemiological Characteristics of Dorsal and Lumbar Spine Trauma Presenting to a Trauma Hospital in Kathmandu, Nepal: Formulation of a National Spine Policy

“…Hence, early surgery should be attempted as emphasized by Haroop JS et al to bring about a favorable neurological outcome 10 .…”

Improving the therapeutic efficacy of neural progenitor cell transplantation following spinal cord injury

“…While a great deal of experimental work has focused on the acute transplantation of NPCs into the injured spinal cord [15,28,33], the time point used do not typically match the time at which injured people can be treated. To treat patients acutely they must first be transported to a trauma center and be medically stable enough to undergo invasive surgical procedures that are usually required for cell delivery [37]. With a more directed focus on regeneration and repair rather than limiting the early stages of inflammation and damage, delayed transplantation of NPCs has shown therapeutic efficacy in either subacute or chronic injury [26,38–40].…”