Evaluaciónde costo-efectividad de la vacuna anti-rotavirus en Chile

Constenla, Dagna; O’Ryan, Miguel; Navarrete, María S; Antil, Lynn; Rheingans, Richard

doi:10.4067/s0034-98872006000600002

Cited by 24 publications

(4 citation statements)

References 8 publications

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“…In addition, as explained above, assuming severe and moderate diarrhea occur mainly during the first rotavirus infection, it was decided that the milder cases of diarrhea that do not require medical treatment should be underestimated. Although the costs associated with these mild events are lower than the costs associated with moderate and severe diarrhea, and several cost-effectiveness studies did not consider them in their analysis (10,(12)(13), mild cases are numerous and probably represent significant costs under the societal perspective.…”

Section: Discussionmentioning

confidence: 99%

“…Applying a similar approach to those used in other studies (8)(9)(10)(11)(12)(13)(14), a decision-tree model was constructed to examine the possible clinical and economic effects of rotavirus infection with and without routine vaccination of children.…”

Section: Model Designmentioning

confidence: 99%

“…Cost-effectiveness analyses in other countries have shown rotavirus vaccination to be cost-effective (8)(9)(10)(11)(12)(13)(14). However, results of economic evaluations are highly sensitive to local parameters, such as incidence, mortality, healthcare and hospitalization costs, and vaccine costs.…”

mentioning

confidence: 99%

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Cost-effectiveness analysis of routine rotavirus vaccination in Brazil

Soárez

Valentim

Sartori

et al. 2008

Rev Panam Salud Publica

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Section: Discussionmentioning

confidence: 99%

Section: Model Designmentioning

confidence: 99%

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Cost-effectiveness analysis of routine rotavirus vaccination in Brazil

Soárez

Valentim

Sartori

et al. 2008

Rev Panam Salud Publica

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“…Este estudo é uma avaliação econômica do tipo análise de custo-efetividade (ACE), ainda a forma dominante para avaliações econômicas de vacinas contra o rotavírus na literatura internacional (Smith et al, 1995;Tucker et al, 1998;Carlin et al, 1999;Podewils et al, 2005;Fisher et al, 2005;Constenla et al, 2006;Rheingans et al, 2007).…”

Section: Descrição Do Modelo Utilizadounclassified

Avaliações econômicas de programas de vacinação: as estimativas de custos em intervenções preventivas

Valentim¹

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analyse the conditions of use, difficulties and repercussions of different cost estimates methods in the cost-effectiveness studies of two specific technologies, vaccines against rotavirus and varicella, as well as the relationship between the cost estimates and the results. The cost estimates are conditioned by general characteristics of the disease under analysis (acute in the case of rotavirus and with long-term disability in the case of varicella), general methodological issues (theoretical choice, methods and sources of data) and specificities to the Brazilian case. This thesis brings a more detailed estimation of direct medical costs, with the inclusion of specific costs of the private health care system for the two diseases, inclusion of public participation for dispensing drugs in the case of rotavirus and inclusion of drugs costs in the public health care system in the case of varicella. As a result, there was an estimated disease total cost increase of 16% for rotavirus and 11% for varicella, as well as increase of savings (disease total cost avoided) of 18% and 16%, respectively, with the introduction of each vaccine. Although the more detailed cost estimates have reduced the incremental cost-effectiveness ratio by 20% for rotavirus and 4% for varicella, the cost-effectiveness level of the two vaccination programs was not altered. The results of the economic evaluations of vaccination against rotavirus and varicella were more sensitive to the vaccination program cost estimates, especially the vaccine price, pointing out the relevance of the cost of the technology under analysis for incorporation comparatively to the other costs. Descriptors: cost-benefit analysis; costs; vaccines; vaccines against rotavirus; vaccine against varicella Tabela 4. Análise de sensibilidade univariada, estimativas de custos e desconto, rotavírus

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A Systematic Review of Economic Evaluation Methodologies Between Resource-Limited and Resource-Rich Countries: A Case of Rotavirus Vaccines

Thiboonboon

Santatiwongchai

Chantarastapornchit

et al. 2016

Appl Health Econ Health Policy

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Although the quality of economic evaluations in LMICs was not as high as those from HICs, it is of an acceptable level given several limitations that exist in these settings. However, the results of this study may not reflect the fact that LMICs have developed a better research capacity in the domain of health economics, given that most of the studies were in theory led by researchers from HICs. Putting more effort into fostering the development of both research infrastructure and capacity building as well as encouraging local engagement in LMICs is thus necessary.

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Evaluaciónde costo-efectividad de la vacuna anti-rotavirus en Chile

Abstract: (Rev Méd Chile 2006; 134: 679-88).

Cited by 24 publications

References 8 publications

Cost-effectiveness analysis of routine rotavirus vaccination in Brazil

Cost-effectiveness analysis of routine rotavirus vaccination in Brazil

Avaliações econômicas de programas de vacinação: as estimativas de custos em intervenções preventivas

A Systematic Review of Economic Evaluation Methodologies Between Resource-Limited and Resource-Rich Countries: A Case of Rotavirus Vaccines

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