Eurycoma longifolia Jack Enhances Sexual Motivation in Middle Aged Male Mice

Abstract

Eurycoma longifolia Jack was investigated for sexual motivation activity in adult, middle-aged male mice and in retired breeders, using the modified open field and the modified runway choice methods. Each mouse received 500 mg/kg of one of 4 fractions of E. longifolia Jack, viz. chloroform, methanol, butanol, and water, whereas the mice in the control and yohimbine groups received 3 ml/kg of normal saline and 30 mg/kg of yohimbine daily respectively for 10 d. The results show a transient increase in the percentage of male mice responding to the right choice after chronic consumption of the fractions with 50 percent of the adult middle-aged male mice treated with E. longifolia Jack and yohimbine scoring the right choice after 8 and 5 days post-treatment respectively. In conclusion, this study has shown that E. longifolia Jack continues to enhance sexual motivation in adult, middle-aged male mice and in retired breeders.

Ethnobotanical study of medicinal plants used by the Jah Hut peoples in Malaysia

“…[3][4][5][6][7][8][9][10][11][12] It is a popular herb used by many local races of Malaysia and mainly used as aphrodisiac, antipyretic and anti-malarial remedy. [39] Not surprisingly, Jah Hut people often use it as an aphrodisiac remedy.…”

“…This is not the only source of income, but also an extension anti-hyperglycemic, anti-malarial, antiproliferative, anti-schistosomal, anxiolytic and aphrodisiac activities are found in both in vivo and in vitro studies. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] Jah Hut people often use M. citrifolia to treat boils by topical application of leaves or fruits. This coincides with pharmacological validation, since boils (impetigo, folliculitis, furuncles, or carbuncles) are often caused by Staphylococcus aureus; M. citrifolia possess anti-bacterial properties to counter it.…”

Cytotoxic effects of the root extracts ofEurycoma longifolia Jack

“…Previous chemical studies had revealed the presence of quassinoids, alkaloids, triterpenes and steroidal compounds in this root and other plant parts and new compounds are still being characterized (Kuo et al, 2004;Bedir et al, 2003;Choo and Chan, 2002;Ang et al, 2002Ang et al, , 2003Morita et al, 1993;Itokawa et al, 1992Itokawa et al, , 1993Kardono et al, 1991;Chan et al, 1986;Darise et al, 1982;Thoi and Suong, 1970). Not every compound has been screened to prove its traditional claims since the amount isolated is very low in yield (in µg; <0.05% from the dry weight of raw material).…”

“…Its roots have gained tremendous popularity among herbal consumers due to many claims of its various therapeutic effects including aphrodisiac and tonic properties (Burkill, 1966;Perry, 1980;Soepadmo and Wong, 1996) that were also supported by many preliminary scientific reports (Ang et al, 2003(Ang et al, , 2002Ang and Ngai, 2001).…”

A new herbal combination, Etana, for enhancing erectile function: an efficacy and safety study in animals

“…The medicinal activity of Panax quinquelotius (Ginseng) has improved penile rigidity, libido and patient satisfaction in men with ED, 4,5 whereas using a Eurycoma longifolia extract (Tongkat Ali) and Epimedium grandiflorum (Horny Goat Weed) in animals increased sexual arousal, motivation and frequency of sexual activity. [6][7][8][9][10] Furthermore, there are some natural products that could play a role in improving circulation to the prostate and penis such as Centella asiatica (Gotu Kola) and flower pollen. [11][12][13] Therefore, it was our hypothesis that the development of a herbal combination of the above five plant extracts, called Etana, 14 could work on several age-induced causes of ED.…”