European evidence-based Consensus on the management of ulcerative colitis: Current management

Operative Outcomes of Open versus Laparoscopic Total Proctocolectomy with Ileal Pouch Anal Anastomosis in Ulcerative Colitis

“…9 The first experience of a total colectomy with ilealpouch anal anastomosis (TPC-IPAA) was described in 1978 by Parks et al 10 Currently, TPC-IPAA is widely performed, and the European Crohn' s and Colitis Organization designated it as a standard technique. 11 With the development of the laparoscopic technique, the proportion of laparoscopic surgery has increased. In the field of IBD including UC, laparoscopic surgery has not been performed much because of bowel inflammation and anatomical variations owing to the IBD itself.…”

A model of the long‐term cost effectiveness of scheduled maintenance treatment with infliximab for moderate‐to‐severe ulcerative colitis

“…4 Clinical guidelines issued by the European Society of Crohn's and Colitis (ECCO) recommend a scheduled maintenance treatment (SMT) with IFX for patients responding to IFX induction therapy. 5 The efficacy of IFX in the treatment of moderatesevere UC patients has been demonstrated in two randomized controlled trials where the drug was added to an existing regimen of standard care. ACT I and ACT II investigated the efficacy of IFX SMT (5 mg ⁄ kg) in patients with moderate-severe active UC for 54 weeks and 30 weeks, respectively.…”

Systematic review: steroid withdrawal in anti‐TNF‐treated patients with inflammatory bowel disease

“…In the current guidelines, a step-up approach is advised, starting with the least effective and simultaneously least toxic medication. [1][2][3][4] Mesalazine (mesalamine) is the initial treatment for mild-to-moderate UC. [5][6][7] After this regimen fails, corticosteroids and immunosuppressants are initiated.…”