“…It was postulated that dehydrogenation could follow to yield 3,4-dehydroisolubimin (83) : there was tentative evidence, based on GC-MS, for the presence of this compound as a transient intermediate. Cyclization would then afford cyclodehydroisolubimin (84) as the precursor of cyclolubimin (85) and of the epoxides (86) and (87). The intermediacy of ( 83) is consistent with observed incorporation of a deuterium atom at C-3 of (84) following incubation of lubimin with G .…”