Étude comparative de l’insuffisance rénale aiguë communautaire chez le sujet VIH positif et le sujet VIH négatif : expérience d’un service de médecine interne à Abidjan (Côte d’Ivoire)

Yao, Kouamé Hubert; Tanon, Aristophane; Lagou, Adjoua Delphine; Konan, Serge Didier; Diopoh, Sery Patrick; Meite, Fatou

doi:10.1016/j.nephro.2016.10.003

Cited by 4 publications

(10 citation statements)

References 36 publications

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“…The female predominance of HIVinfected patients in our work complies with WHO data showing that there is a feminization of the HIV epidemic, especially in sub-Saharan Africa where women represent 61% of all infected adults [14]. This feminization of HIV infection has been found in some studies [5]. This female vulnerability is not only related to the susceptibility of heterosexual transmission, but also to the difficult socioeconomic conditions women face [15].…”

Section: Discussionsupporting

confidence: 86%

“…HIV prevalence was 48.07% in the surveyed ARF population. This prevalence was higher than that observed by KH Yao et al [5] in Ivory Coast on a population of 414 patients (35.20%) and even higher than that found in the Vachiat et al [6] series (14.8%) in South Africa, on a total of patients. However, our prevalence was similar to that found by de Ahoui et al [7] in Cotonou (44.19%) in HIV-infected patients newly put on HAART.…”

Section: Discussioncontrasting

confidence: 57%

“…On the other hand, the selection bias in relation to our study scope would certainly have resulted in an increase in HIV prevalence in our ARF population. Indeed, the highest prevalences were found in studies [7] whose scope included the infectious disease department compared to studies whose scope included only nephrology and/or internal medicine services [5] [6]. Nevertheless, HIV prevalence remains high in the population of sub-Saharan Africa and leads to significant morbidity including acute renal failure.…”

Section: Discussionmentioning

confidence: 99%

“…Several authors had reported that HIV-infected patients developed ARF at an early age compared to uninfected patients [6] [11] [12] [13]. For example, Wyatt et al [10], Vichiat et al [6], KH Yao et al [5] all reported that HIV-infected patients were significantly younger than those who were not HIV-infected respectively (44.2 years versus 56.6 years; P < 0.001), (37.4 years versus 45.2 years; p < 0.001) and (42 years versus 51 years; p < 0.0001). The female predominance of HIVinfected patients in our work complies with WHO data showing that there is a feminization of the HIV epidemic, especially in sub-Saharan Africa where women represent 61% of all infected adults [14].…”

Section: Discussionmentioning

confidence: 99%

“…Clinically, HIV-infected patients frequently had infectious and related water loss signs during ARF [5] [17]. However, comorbidities such as hypertension and diabetes were more common in uninfected patients.…”

Section: Discussionmentioning

confidence: 99%

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Acute Renal Failure in Hospitals in Togo: Comparative Analysis of HIV Positive Patients and HIV Negative Patients

Tsevi¹,

Bawe²,

Nemi³

et al. 2019

OJNeph

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Introduction: Human Immunodeficiency (HIV) is a risk factor often associated with the occurrence of Acute Renal Failure (ARF). Objectives: To describe the profile of Acute Renal Failure (ARF) in HIV-infected patients and compare them to non-infected patients. Patients and Methods: It was a prospective study from January 2018 to February 2019 that took place in the nephrology, infectious diseases and internal medicine departments of the Sylvanus Olympio University Hospital Center in Lomé (Togo). Results: The prevalence of ARF in HIV-infected patients was 48.07%. HIV-infected patients had an average age of 46.9 ± 11.6 years (p = 0.36) compared to 44.0 ± 20.4 years for non-HIV infected patients. Female sex was predominant in the HIV-infected population with a sex ratio H/F of 0.6 (p < 0.0001) versus 2.9 for the non-infected. The reasons for admission were such as fever (28%), digestive disorders (56%) were more common in HIV-infected patients than non-infected patients (11.1%, 37%). Infected patients had more diarrhea than non-infected patients (24% versus 7.4%) with p = 0.01. They showed more signs of infections than uninfected patients (40% versus 18.5%) with P = 0.02. HIV infection was known before admission in 96% of cases. Patients whose HIV was known before admission had hypertension (16.7%), diabetes (12.5%) and CD4 count < 200 (/mm 3) in 50% of cases. HIV infected patients had more anemia (52.0% versus 22.2%) with p = 0.002. Conclusion: No deaths were recorded in the HIV-infected group.

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Section: Discussionsupporting

confidence: 86%

Section: Discussioncontrasting

confidence: 57%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Acute Renal Failure in Hospitals in Togo: Comparative Analysis of HIV Positive Patients and HIV Negative Patients

Tsevi¹,

Bawe²,

Nemi³

et al. 2019

OJNeph

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Acute kidney injury in HIV‐infected patients: a critical review

et al. 2018

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Acute kidney injury (AKI) is characterized by a rapid decline of renal function associated with worse outcomes. The purpose of the authors is to perform a critical review of the incidence, risk factors, pathogenesis and outcome of AKI in HIV‐infected patients. Human immunodeficiency virus (HIV)‐infected patients have an increased risk of developing AKI, to which contribute both HIV‐dependent and HIV‐independent factors as well as the nephrotoxicity of drugs used. The increased risk of AKI in HIV‐infected patients and its negative impact on prognosis highlights the need for identification of patients at risk, creation of prevention strategies and management. HIV‐infected patients have an increased risk of developing AKI, to which both HIV‐dependent and HIV‐independent factors contribute, as well as the nephrotoxicity of drugs used. The increased risk of AKI in HIV‐infected patients and its negative impact on prognosis highlight the need for identification of patients at risk, creation of prevention strategies and management.

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Profil évolutif de l'insuffisance rénale aiguë chez les personnes vivant avec le VIH à Abidjan, Côte d'Ivoire du 1er janvier 2014 au 31 décembre 2017

Guei¹,

Sidibé²,

Wognin³

et al. 2019

Pan Afr Med J

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En Côte d'Ivoire, la prévalence de l'infection au virus de l'immunodéficience humaine (VIH) est élevée. Tous les organes peuvent être atteints, en particulier le rein. Certaines études en Côte d'Ivoire ont retrouvé les infections opportunistes comme facteur de mauvais pronostic de l'insuffisance rénale aiguë (IRA). L'objectif de cette étude était de rechercher les éventuels autres facteurs associés à l'évolution de l'IRA chez les personnes infectées par le VIH. Une étude rétrospective, analytique, menée au Centre Hospitalier et Universitaire de Yopougon de janvier 2014 à décembre 2017. Etaient inclus tous les patients âgés de plus de 18 ans, infectés par le VIH et ayant présenté une IRA. Soixante-treize (73) patients ont été inclus, soit une prévalence de 24%. L'âge moyen des patients était de 39,32 ± 10,50 ans avec des extrêmes de 18 et 65 ans. Un sexe ratio de 1,6 en faveur des femmes. L'obésité (p=0,047; OR=8,72; IC (95%)=1,07-39,21) et le taux de CD4< 200/mm3 (p=0,000; OR=58,50; IC (95%)=10,31-55,12) étaient associés à un mauvais pronostic de l'IRA. En Côte d'Ivoire, la prévalence hospitalière l'IRA au cours du VIH demeure élevée. Son évolution est défavorable avec le décès ou le passage à la chronicité. En plus de l'immunodépression profonde déjà connue comme facteur de mauvais pronostic, cette étude a montré que l'obésité était associée à une évolution défavorable de l'IRA chez les personnes vivant avec le VIH.

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Étude comparative de l’insuffisance rénale aiguë communautaire chez le sujet VIH positif et le sujet VIH négatif : expérience d’un service de médecine interne à Abidjan (Côte d’Ivoire)

Cited by 4 publications

References 36 publications

Acute Renal Failure in Hospitals in Togo: Comparative Analysis of HIV Positive Patients and HIV Negative Patients

Acute Renal Failure in Hospitals in Togo: Comparative Analysis of HIV Positive Patients and HIV Negative Patients

Acute kidney injury in HIV‐infected patients: a critical review

Profil évolutif de l'insuffisance rénale aiguë chez les personnes vivant avec le VIH à Abidjan, Côte d'Ivoire du 1er janvier 2014 au 31 décembre 2017

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