Profil évolutif de l'insuffisance rénale aiguë chez les personnes vivant avec le VIH à Abidjan, Côte d'Ivoire du 1er janvier 2014 au 31 décembre 2017

Guei, Monlet Cyr; Sidibé, M.; Wognin, Anastasie; Konan, Serge Didier; Choho, Motochi Carole; Yao, Hubert Kouamé; Ackoundou-N’Guessan, Clément; Gnionsahé, Appolinaire

doi:10.11604/pamj.2019.34.2.20016

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…AKI occurs most often in advanced disease and may also be secondary to the use of nephrotoxic drugs common in these patients or to shock. A prospective study of 317 HIV-infected patients in Abidjan (in Ivory Coast) found AKI in 76 patients (24%) [ 75 ]. In a cohort of 101 HIV-infected South Africans with AKI, the most common cause of AKI was sepsis (60%), followed by volume depletion and haemodynamic instability [ 76 ].…”

Section: Factors Associated With Aki In Sub-saharan Africamentioning

confidence: 99%

Prevalence and Factors Associated with Acute Kidney Injury in Sub-Saharan African Adults: A Review of the Current Literature

Kahindo

Mukuku

Wembonyama

et al. 2022

International Journal of Nephrology

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Acute kidney injury (AKI) is a complex condition that can occur in both community and hospital settings and has many aetiologies. These aetiologies may be infectious, toxic, surgical, or related to the different management methods. Although it is a major public health problem worldwide, it must be emphasised that both its incidence and mortality rate appear to be very high in sub-Saharan African (SSA) countries compared to developed countries. The profile of AKI is very different from that of more developed countries. There are no reliable statistics on the incidence of AKI in SSA. Infections (malaria, HIV, diarrhoeal, and other diseases), nephrotoxins, and obstetric and surgical complications are the main aetiologies in Africa. The management of AKI is costly and associated with high rates of prolonged hospitalisation and in-hospital mortality.

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Section: Factors Associated With Aki In Sub-saharan Africamentioning

confidence: 99%

Prevalence and Factors Associated with Acute Kidney Injury in Sub-Saharan African Adults: A Review of the Current Literature

Kahindo

Mukuku

Wembonyama

et al. 2022

International Journal of Nephrology

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Determinants of virological failure in HIV1 infected patients followed in a third-level hospital Abidjan, Cote d’Ivoire

Pacome,

Syndou,

Brittoh

et al. 2023

IJMR

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: Côte d'Ivoire has been committed to achieving the UNAIDS 90-90-90 targets of People Living with HIV (PLHIV) follow-up since 2015. The proportion of patients on antiretroviral therapy (ART) was below the desired rates for 2020. The laboratory of the University Hospital Center (CHU) of Yopougon has been equipped with instruments capable of quantifying the plasma viral load (VL) of PLHIV on ART. This quantification allowed for early detection of virological failure in PLHIV. The objective of this study was to determine the rate of virological failure and the epidemiological, immunological and virological determinants of virological failure in patients followed at the Yopougon University Hospital in Abidjan. : This was a retrospective study covering the period from January 1, 2015 to October 31, 2019. It was carried out on data related to blood samples (plasma) of PLHIV (infected with HIV-1) under ART for at least 6 months and who had quantified their viral load.: A total of 52356 PLHIV were included in this study. The age group 40-50 years comprised the majority of the patients (46.7%) with a median age of 40 +/- 0.3 years. The female sex predominated with 72% and a sex ratio of (M/F) = 0.38. The TCD4 cell were between 500 and 350 cells/µL in 57.0% of patients at treatment initiation. The TDF+3TC+EFV treatment regimen was prescribed in the majority of patients (88.62%). The population of patients with virological failure (defined as VL ≥ 1000 copies/ml) was 12924 or a prevalence of 24.7%. The determinants of virological failure were age ≤ 15 years, male sex and CD4+ LT rate below 250 cells/µL (p <0.05).: The virological failure rate was high especially in children and male subjects at the Yopougon University Hospital. It appears therefore important to act on these determinants, by additional efforts through concrete actions such as regular and systematic measurement of CV at the time of rapid change of treatments with effective combinations for this type of PLHIV. The goal is to achieve the objectives of the UNAIDS to eradicate HIV by 2030.

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Profil évolutif de l'insuffisance rénale aiguë chez les personnes vivant avec le VIH à Abidjan, Côte d'Ivoire du 1er janvier 2014 au 31 décembre 2017

Cited by 2 publications

References 17 publications

Prevalence and Factors Associated with Acute Kidney Injury in Sub-Saharan African Adults: A Review of the Current Literature

Prevalence and Factors Associated with Acute Kidney Injury in Sub-Saharan African Adults: A Review of the Current Literature

Determinants of virological failure in HIV1 infected patients followed in a third-level hospital Abidjan, Cote d’Ivoire

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