Etiology, antimicrobial susceptibility profiles, and mortality associated with bacterial meningitis among children in Egypt

Outcome and prognostic factors of acute meningoencephalitis in children of Southern Bangladesh

“…Single fatality was noticed with bacterial meningitis due to S pneumoniae. The case fatality (24%) for all types of meningoencephalitis in Egypt is higher than what is reported from United States and Europe possibly due to high level of antimicrobial resistance 20 . In another study, mean case fatality was 16% and fatality in bacterial meningitis was 36% compared to 14% in bacterial negative group 14,19 .…”

Acute bacterial meningitis among children under 5 years of age in Oman: a retrospective study during 2000-2005

“…There were seven deaths (2%) among children reported due to meningitis. Similar gender difference and case-fatality rate due to meningitis among children are provided in many published studies [16,17]. Information on vaccination status versus Hib was available for the study cohort but was lacking for pneumococcal and meningococcal vaccines.…”

Adult and paediatric mortality patterns in a referral hospital in Liberia 1 year after the end of the war

“…However, the adult and paediatric CFRs were similar in all the hospitals. In other African hospitals the meningitis fatality rate is variable: 20% in Mali 29 , 24% in Egypt 36 , 33% in Zimbabwe 28 , 37% in Ghana 37 , 38% in Uganda 13 , 40% in Malawi 38 , 42% in Nigeria 39 and 51% in Tanzania 40 .…”

“…However in hospitalized children, this figure is higher: 18% in Niger 42 and 23% in Egypt. 36 Ceftriaxone has been validated for the treatment of meningitis in several studies due to the high pathogen sensitivity to this antibiotic. 36,39 Even though the time between the first symptoms and arrival to the hospital could be a major prognostic factor, 40 the delay in the administration of the first dose of antibiotic probably also contributed to the meningitis fatality rate.…”