2010
DOI: 10.1016/j.ijid.2009.03.035
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Etiology and clinico-epidemiological profile of acute viral encephalitis in children of western Uttar Pradesh, India

Abstract: Enterovirus 71, the major etiology of VE in our study, was associated with significant mortality and morbidity. Such studies should be conducted frequently to assess the role of emerging VE in different regions.

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Cited by 60 publications
(52 citation statements)
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“…Before the start of nationwide MMR vaccination programs in countries like Finland in 1980s, measles and mumps viruses were most commonly associated with encephalitis in children (16). These organisms have almost disappeared from developed countries (17); however, they continue to be important causative agents of AES in developing countries like India (18)(19)(20), probably because of suboptimal immunization rates. Enteroviruses were not detected in the current study, although EVs were detected in 21.6z and 41.11z patients in 2006 (21) and 2008 (22), respectively, during outbreaks of AES in UP; the serotypes involved in both the outbreaks were different, with similarity to EV-89 and EV-76 in 2006 and to coxsackievirus B5 and echovirus 19 in 2008.…”
Section: Discussionmentioning
confidence: 99%
“…Before the start of nationwide MMR vaccination programs in countries like Finland in 1980s, measles and mumps viruses were most commonly associated with encephalitis in children (16). These organisms have almost disappeared from developed countries (17); however, they continue to be important causative agents of AES in developing countries like India (18)(19)(20), probably because of suboptimal immunization rates. Enteroviruses were not detected in the current study, although EVs were detected in 21.6z and 41.11z patients in 2006 (21) and 2008 (22), respectively, during outbreaks of AES in UP; the serotypes involved in both the outbreaks were different, with similarity to EV-89 and EV-76 in 2006 and to coxsackievirus B5 and echovirus 19 in 2008.…”
Section: Discussionmentioning
confidence: 99%
“…In contrast to the study findings by Beig FK et al in children of western Uttar Pradesh, India. 22 This difference in etiological findings of suspected AES cases is due to the geographic features of this region which favour in spread of JEV-an abundance of rice fields and high temperature and relative humidity, provides a suitable environment for JEV transmission. 23 UP alone contributes to 70-75% of total disease burden in India.…”
Section: Diagnosismentioning
confidence: 99%
“…16 Laporan proporsi kejadian ensefalitis Herpes simpleks sendiri di literatur dunia sangat bervariasi mulai dari 1% hingga 30% dari kasus ensefalitis pada anak. 24,25 Terlepas dari singkatnya waktu penelitian, ini merupakan studi pertama di Indonesia yang berusaha mengidentifikasi besarnya kejadian ensefalitis Herpes simpleks pada anak berdasarkan pemeriksaan PCR cairan serebrospinal. Tidak ditemukannya hasil pemeriksaan PCR yang positif bukan berarti kejadian ensefalitis Herpes sangat langka di Sumatera Barat atau Indonesia pada umumnya.…”
Section: Pcr Herpes Simpleksunclassified