ETHYLENE RESPONSE FACTOR39–MYB8 complex regulates low-temperature-induced lignification of loquat fruit

Zhang, Jing; X, Yin; Li, Heng; Xu, Meng; Zhang, Meng-Xue; Li, Shaojia; Liu, Xincheng; Shi, Yanna; Grierson, Donald; Chen, Kunsong

doi:10.1093/jxb/eraa085

Cited by 62 publications

(41 citation statements)

References 78 publications

(126 reference statements)

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“…BT2, BTB domain contained protein; KFBs, Kelch Domain F-Box proteins; MdMIEL, MYB30-INTERACTING E3 LIGASE 1 in apple; OsFBK1, F-box protein containing Kelch 1 in rice; OsGRF8, GROWTH REGULATING FACTOR 8 in rice; OsUCL23, uclacyanin family in rice; PA, proanthocyanidins; PtoUBC34, E2 ubiquitin-conjugating enzyme 34 in Populus tomentosa; SPL, SQUAMOSA PROMOTER BINDING PROTEIN-LIKE. (Zhang et al, 2020c). OsMYB30 binds to and activates the promoters of Os4CL3 and Os4CL5, and brings about the accumulation of G and S lignin in rice (Li et al, 2020e).…”

Section: Transcriptional Regulationmentioning

confidence: 99%

Contribution of phenylpropanoid metabolism to plant development and plant–environment interactions

Dong

Lin

2021

JIPB

702

429

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Phenylpropanoid metabolism is one of the most important metabolisms in plants, yielding more than 8,000 metabolites contributing to plant development and plant-environment interplay. Phenylpropanoid metabolism materialized during the evolution of early freshwater algae that were initiating terrestrialization and land plants have evolved multiple branches of this pathway, which give rise to metabolites including lignin, flavonoids, lignans, phenylpropanoid esters, hydroxycinnamic acid amides, and sporopollenin. Recent studies have revealed that many factors participate in the regulation of phenylpropanoid metabolism, and modulate phenylpropanoid homeostasis when plants undergo successive developmental processes and are subjected to stressful environments. In this review, we summarize recent progress on elucidating the contribution of phenylpropanoid metabolism to the coordination of plant development and plantenvironment interaction, and metabolic flux redirection among diverse metabolic routes. In addition, our review focuses on the regulation of phenylpropanoid metabolism at the transcriptional, post-transcriptional, post-translational, and epigenetic levels, and in response to phytohormones and biotic and abiotic stresses.

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Section: Transcriptional Regulationmentioning

confidence: 99%

Contribution of phenylpropanoid metabolism to plant development and plant–environment interactions

Dong

Lin

2021

JIPB

702

429

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“…Previous studies have demonstrated that EjAP2-1 works in coordination with EjMYB1 and EjMYB2 for transcriptional regulation of Ej4CL1 ( Zeng et al, 2015 ). Zhang et al (2020) recently found that the EjERF39 and EjMYB8 protein complex activates Ej4CL1 by protein-DNA interaction with the promoter of Ej4CL1 . Furthermore, utilization of the loquat transcriptome has allowed for the discovery of more lignification-related transcription factors ( Lin et al, 2018 ; Liu et al, 2019 ).…”

Section: Discussionmentioning

confidence: 99%

“…According to previous studies, ectopic expression of MYB ( Xu et al, 2014b ; Wang et al, 2016 ), NAC (NAM, ATAF1, ATAF2, and CUC2; Ge et al, 2017 ), APETALA2/Ethylene Response Factor (AP2/ERF; Zeng et al, 2015 ; Zhang et al, 2020 ), Heat Shock Factor (HSF; Zeng et al, 2016 ), and Homobox from Arabidopsis thaliana (HAT; Xu et al, 2019b ) family members in loquat flesh resulted in changes in the expression of phenylpropanoid pathway genes. For example, the transcripts of Ej4CL1 can be induced by EjERF39 and EjHSF1 or repressed by EjAP2-1 and EjbHLH1, resulting in changes in the lignin content ( Zeng et al, 2015 , 2016 ; Xu et al, 2019b ; Zhang et al, 2020 ). EjNAC3 and EjHAT1 can modify the expression of EjCAD -like and EjCAD5 , respectively ( Ge et al, 2017 ; Xu et al, 2019b ).…”

Section: Introductionmentioning

confidence: 94%

“…Similarly, EjbHLH1 inhibits the transcription of Ej4CL1 by forming a protein complex with EjMYB2 ( Xu et al, 2019a ). In addition, the transcripts of Ej4CL1 that increased due to EjMYB8 could be further induced by the synergism between EjERF39 and EjMYB8 ( Zhang et al, 2020 ). Thus, lignin biosynthesis can be regulated by protein-protein interactions with MYBs, which is a strategy frequently adopted by transcription factors that cannot directly bind to promoters of genes in the phenylpropanoid pathway.…”

Section: Introductionmentioning

confidence: 99%

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The MADS-Box Transcription Factor EjAGL65 Controls Loquat Flesh Lignification via Direct Transcriptional Inhibition of EjMYB8

Shi

Zhang

et al. 2021

Front. Plant Sci.

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Loquat fruit accumulates lignin in its flesh when undergoing chilling injury during postharvest storage, making it a suitable model for the study of flesh lignification. Transcriptional regulation of lignin biosynthesis is principally controlled by the NAC-MYB transcriptional cascade in model plants. Previous research has demonstrated that EjMYB8 activates lignin biosynthesis through direct interaction with the promoter of Ej4CL1. However, the classic NAC-MYB gene regulation network has not been established. Here, the MADS-box gene EjAGL65 was discovered by screening a cDNA library using the EjMYB8 promoter as bait in yeast. A phylogenetic analysis and structural comparisons revealed that EjAGL65 belongs to the Mδ subgroup of the MADS-box family, whose members have not been reported as being involved in the regulation of lignin deposition. EjAGL65 transcription was downregulated at 0°C compared to 5°C, indicating a negative correlation with the change of lignin content. A dual-luciferase assay indicated that EjAGL65 is capable of inhibiting the promoter activity of EjMYB8 in vivo. These results showed that the Mδ MADS-box gene EjAGL65 transcriptionally regulates EjMYB8 during postharvest chilling induced flesh lignification, which differs from the classical regulation model of lignin biosynthesis that has been illustrated for developmental lignin accumulation.

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“…However, whether and how the expression of StInvInh2 is regulated by cold-responsive regulators is not clear. Interestingly, the StInvInh2 promoter contains a dehydration-responsive element/C-repeat (DRE/CRT) motif, which is generally bound by APETALA2/ethylene-responsive factor (AP2/ERF) TFs 19 , 20 . Therefore, cold-responsive AP2/ERFs could be considered candidate regulators of StInvInh2 transcription in cold-stored potato tubers.…”

Section: Introductionmentioning

confidence: 99%

StRAP2.3, an ERF‐VII transcription factor, directly activates StInvInh2 to enhance cold-induced sweetening resistance in potato

Shi¹,

Song²,

Liu³

et al. 2021

Hortic Res

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Potato invertase inhibitor (StInvInh2) positively regulates cold-induced sweetening (CIS) resistance by inhibiting the activity of vacuolar invertase. The distinct expression patterns of StInvInh2 have been thoroughly characterized in different potato genotypes, but the related CIS ability has not been characterized. The understanding of the regulatory mechanisms that control StInvInh2 transcription is unclear. In this study, we identified an ERF‐VII transcription factor, StRAP2.3, that directly regulates StInvInh2 to positively modulate CIS resistance. Acting as a nuclear-localized transcriptional activator, StRAP2.3 directly binds the ACCGAC cis-element in the promoter region of StInvInh2, enabling promoter activity. Overexpression of StRAP2.3 in CIS-sensitive potato tubers induced StInvInh2 mRNA abundance and increased CIS resistance. In contrast, silencing StRAP2.3 in CIS-resistant potato tubers repressed the expression of StInvInh2 and decreased CIS resistance. We conclude that cold-responsive StInvInh2 is due to the binding of StRAP2.3 to the ACCGAC cis-element in the promoter region of StInvInh2. Overall, these findings indicate that StRAP2.3 directly regulates StInvInh2 to positively modulate CIS resistance, which may provide a strategy to improve the processing quality of potatoes.

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ETHYLENE RESPONSE FACTOR39–MYB8 complex regulates low-temperature-induced lignification of loquat fruit

Cited by 62 publications

References 78 publications

Contribution of phenylpropanoid metabolism to plant development and plant–environment interactions

Contribution of phenylpropanoid metabolism to plant development and plant–environment interactions

The MADS-Box Transcription Factor EjAGL65 Controls Loquat Flesh Lignification via Direct Transcriptional Inhibition of EjMYB8

StRAP2.3, an ERF‐VII transcription factor, directly activates StInvInh2 to enhance cold-induced sweetening resistance in potato

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