Ethyl acetate for the desorption of a liquid chromatographic precolumn on‐line into a gas chromatograph

Vreuls, J. J.; Cuppen, W. J. G. M.; Jong, Gerhardus J. de; Brinkman, U.A.Th.

doi:10.1002/jhrc.1240130303

Cited by 40 publications

(9 citation statements)

References 15 publications

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“…In the on-line analysis, a short LC column packed with a PLRP-S solid-phase extraction material was used for preconcentration of pollutants from water. Ethyl acetate was used for desorption [35]. To introduce the desorption solvent into the GC system, the PTV injector was used as the interface.…”

Section: Resultsmentioning

confidence: 99%

Programmed‐temperature injector for large‐volume sample introduction in capillary gas chromatography and for liquid chromatography‐gas chromatography interfacing

Staniewski

Janssen

Cramers

et al. 1992

J Microcolumn Separations

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The introduction of large sample volumes in capillary gas chromatography is becoming increasingly important in various application areas. Especially in the analysis of very dilute sample (e.g., environmental samples) and in coupled LC‐GC, large volume sampling is extremely important. Programmed‐temperature sample introduction is shown to be an attractive technique for these purposes. In this paper we present some applications of large volume sampling in environmental analysis. Water samples were analyzed using both off‐line and on‐line extraction with gas chromatography (GC) analysis. In the off‐line method, pollutants were extracted into hexane or methylene chloride. Using the programmed‐temperature injector, up to 250 μL of the extract could be introduced into the GC system. In this way, reproducible quantitative analysis of PAHs and herbicides were achieved at sub‐ppb concentrations using flame ionization detection. In the on‐line mode, pollutants were preconcentrated on a short liquid chromatography (LC) column packed with a PLRP‐S solid phase extraction material. After the trapping step, the components were desorbed by ethyl acetate and transferred directly into the programmed‐temperature vaporizer (PTV‐GC) system. Using this method, detection limits below about 1 ppb of herbicides in water were obtained.

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Section: Resultsmentioning

confidence: 99%

Programmed‐temperature injector for large‐volume sample introduction in capillary gas chromatography and for liquid chromatography‐gas chromatography interfacing

Staniewski

Janssen

Cramers

et al. 1992

J Microcolumn Separations

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show abstract

“…Since water is not a good solvent for GC, primarily because it hydrolyses the siloxane bonds in GC columns causing deterioration of the column performance, the introduction of water directly to GC should be avoided. After trapping, and before elution of the analytes, the SPE column is often dried with a gas flow, or the extract is dried with a separate drying column packed with copper sulphate or silica to remove water, which is placed after the SPE column [5,6,9,10]. Of these techniques, the use of a nitrogen purge is the more straightforward and easy-to-use.…”

Section: Solid-phase Extractionmentioning

confidence: 99%

“…Methods based on both SPE-GC and LLE-GC have been developed for a variety of environmental determinations, and SPE-GC has also been used for the analysis of drugs in biological fluids [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,53,54,55,56,57,58,59,60,61,62,…”

Section: Liquid Samplesmentioning

confidence: 99%

Approaches for on-line coupling of extraction and chromatography

Hyötyläinen

Riekkola

2004

Analytical and Bioanalytical Chemistry

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This review provides an overview of the approaches available in order to perform on-line coupling of various extraction techniques with liquid and gas chromatography, for the analysis of semivolatile and nonvolatile analytes in liquid and solid samples. The main focus is on the instrumental set-up of these techniques. Selected real applications are described by way of illustration. The extraction methods suitable for on-line coupling covered in this review are: liquid-liquid extraction, solid-phase extraction, membrane-based techniques, pressurised liquid extraction, supercritical fluid extraction, and microwave- and sonication-assisted extractions. The following systems are not covered in this review: on-line coupled solid-phase extraction-liquid chromatography, purge-and-trap-GC, and membrane extraction with a sorbent interface-GC.

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“…The coupled SPE procedures are essentially the same as off-line ones, in both cases involving conditioning of the SP material before loading of the sample. Typically, after trapping, and before elution of the analytes, the SPE column is dried [25,[27][28][29][30]. The extract is then directly transferred to the GC interface where the final separation takes place.…”

Section: On-line Coupling Of Solid-phase Extraction With Gas Chromatomentioning

confidence: 99%

Solid-phase extraction or liquid chromatography coupled on-line with gas chromatography in the analysis of biological samples

Hyötyläinen

Riekkola

2005

Journal of Chromatography B

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Ethyl acetate for the desorption of a liquid chromatographic precolumn on‐line into a gas chromatograph

Cited by 40 publications

References 15 publications

Programmed‐temperature injector for large‐volume sample introduction in capillary gas chromatography and for liquid chromatography‐gas chromatography interfacing

Programmed‐temperature injector for large‐volume sample introduction in capillary gas chromatography and for liquid chromatography‐gas chromatography interfacing

Approaches for on-line coupling of extraction and chromatography

Solid-phase extraction or liquid chromatography coupled on-line with gas chromatography in the analysis of biological samples

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