Ethnopharmacological survey of medicinal plants in Nor-Yauyos, a part of the Landscape Reserve Nor-Yauyos-Cochas, Peru

Rehecho, Sheyla; Uriarte-Pueyo, Iñigo; Calvo, Javier Martínez; Vivas, Luz Amanda; Calvo, María Isabel

doi:10.1016/j.jep.2010.09.006

Cited by 88 publications

(49 citation statements)

References 57 publications

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“…The leaves, stems and flowers from Jungia paniculata (J. paniculata) are used to disinfect external cuts and to treat urinary tract inflammation, amigdalitis, tonsillitis, stomach ulcers, nephritis and haemorrhoids, as well as an antibacterial agent in traditional medicine in South America (De-La-Cruz et al 2007;Hammond et al 1998;Rehecho et al 2011). Additionally, the leaves and stems from J. paniculata are used as a depurative of blood in traditional medicine in South America (Goleniowski et al 2006).…”

Section: Introductionmentioning

confidence: 99%

Jungia sellowii suppresses the carrageenan-induced inflammatory response in the mouse model of pleurisy

et al. 2014

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This study was conducted to explore the anti-inflammatory effect of Jungia sellowii (Asteraceae) using a murine model of pleurisy induced by carrageenan (Cg). This plant is used in southern Brazil to treat inflammatory diseases. J. sellowii leaves were extracted with ethanol/water to obtain the crude extract (CE), which was fractionated with different solvents, yielding n-hexane (Hex), dichloromethane (DCM), ethyl acetate (EtOAc) and n-butanol (BuOH) fractions, and aqueous fraction (Aq). The major compounds succinic acid (SA) and lactic acid (LA) were isolated from Aq fraction, and their structures were determined by (1)H and (13)C NMR. Pleurisy was induced by Cg (Saleh et al. 1996). The leukocytes, exudation, myeloperoxidase (MPO) and adenosine-deaminase (ADA) activities, metabolites of nitric oxide (NO x ) levels, protein levels and mRNA expression for interleukin 1 beta (IL-1β), tumour necrosis factor alpha (TNF-α), interleukin 17A (IL17A) and inducible of nitric oxide synthase (iNOs), and p65 protein phosphorylation (NF-κB) were analysed 4 h after pleurisy induction. Animals pre-treated with CE, BuOH, Aq, SA, or LA inhibited leukocytes, exudation, MPO and ADA activities, NO x , IL-1β, TNF-α, and IL-17A levels, and the mRNA expression for IL-1β, TNF-α, IL-17A, iNOS, and p65 protein phosphorylation (NF-κB) (p < 0.05). Our study demonstrated that J. sellowii can protect against inflammation induced by Cg by decreasing the leukocytes and exudation. Its effects are related to the decrease of either proinflammatory cytokines and/or NO x . The isolated compounds SA and LA may play an important role in this anti-inflammatory action by inhibiting all the studied parameters. The anti-inflammatory properties of these compounds are due to the downregulation of NF-κB.

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Section: Introductionmentioning

confidence: 99%

Jungia sellowii suppresses the carrageenan-induced inflammatory response in the mouse model of pleurisy

et al. 2014

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“…These studies, associated with the popular use of Tropaeolum majus L. leaves to treatment of acute inflammation, make its use in pregnant women an appealing possibility (Rehecho et al, 2011). In the same way, Gasparotto et al (2009) suggest that the effect of one or more active components of Tropaeolum majus partially facilitates the release of renal prostaglandins in male and female rats.…”

Section: Discussionmentioning

confidence: 99%

Screening for in vivo (anti)estrogenic and (anti)androgenic activities of Tropaeolum majus L. and its effect on uterine contractility

Lourenço

Müller

Boareto

et al. 2012

Journal of Ethnopharmacology

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“…Collection of leaves and then using them as medicine is very easy as compared to roots, flowers and fruits (Giday et al, 2009). Another reason of using leaves could be concerning conservation of the plants, as digging out roots might result in the death of the plant and consequently putting the species in a vulnerable condition (Rehecho et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Ethnobotanical study and phytochemical screening of six medicinal plants used in traditional medicine in the Northeastern Sahara of Algeria (area of Ouargla)

Hadjadj¹,

Bayoussef²,

Hadj-Khelil³

et al. 2015

J. Med. Plants Res.

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An ethnobotanical survey was undertaken to collect information from traditional healers on the use of plants (Atriplex halimus L., Searsia tripartita (Ucria) Moffett, Limoniastrum guyonianum Durieu ex Boiss., Haplophyllum tuberculatum Juss., Tamarix gallica L. and Nitraria retusa (Forssk.) Asch.) in folkloric medicine of Ouargla (Algeria), using a predesigned questionnaire. The studied plants were screened for the presence of secondary metabolites. The traditional healers in the study area used the investigated species for the treatment of various diseases. The average of the informant consensus factor (F IC ) value for all ailment categories was 0.93, with the highest number of species being used for digestive problems (449) followed by dermatological symptoms (154) and nervous disorders (144). These pathologies were mainly treated by leaves in the form of decoction, representing the dominant formulation. The oral administration which regrouped the major form of usage, which was in form of drink, was most exercised. The phytochemical analysis showed the presence of polyphenolic compounds and saponins in almost all tested plants. For the other metabolites classes, results varied between plants. The multi-uses of species demonstrated the importance of these plants and the diversity of the ancestral knowledge.

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Ethnopharmacological survey of medicinal plants in Nor-Yauyos, a part of the Landscape Reserve Nor-Yauyos-Cochas, Peru

Cited by 88 publications

References 57 publications

Jungia sellowii suppresses the carrageenan-induced inflammatory response in the mouse model of pleurisy

Jungia sellowii suppresses the carrageenan-induced inflammatory response in the mouse model of pleurisy

Screening for in vivo (anti)estrogenic and (anti)androgenic activities of Tropaeolum majus L. and its effect on uterine contractility

Ethnobotanical study and phytochemical screening of six medicinal plants used in traditional medicine in the Northeastern Sahara of Algeria (area of Ouargla)

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