Ethnobotanical survey on medicinal plants (Carica papaya L. and Agelanthus dodoneifolius (DC.) Polhill & Wiens) used in the treatment of Hepatitis in Burkina Faso, phytochemistry and antioxidant activity

Abstract

Hepatitis are pathologies of various etiologies affecting millions persons and the management by modern medicines still faces many difficulties. Our study aimed to make a repertory of medicinal plants used in the treatment of hepatitis in the Urbans areas of Bobo-Dioulasso, Dédougou and Fada N'Gourma followed by the phytochemical quantification and antioxidant activity of the most cited ones. We conducted an ethnobotanical survey among traditional Heath practitioners in the three studied locations to achieve this objective. Methanolic extracts of the plant organs were obtained using an extractor apparatus. Polyphenolic compounds contents quantification was done by spectrophotometry using Follin-Ciocalteu reagent and aluminum trichloride. Antioxidant activity was evaluated by three methods (ABTS●+, DPPH●, FRAP) and the reading of optical densities was performed with the spectrophotometer. A total of, 101 traditional healers were interviewed and 52 species were inventoried as being used in hepatitis care in the three localities. Among the species regularly cited in the different localities were Carica papaya (8%) and Agelanthus dodoneifolius (13%), and these two species were selected for the further investigation. Among the parts of plants most used there are roots (45%). Phytochemical investigations of C. papaya and A. dodoneifolius revealed that the best polyphenolic compound content was obtained by the unripe seeds of C. papaya with respectively 14.06±0.68 mg EAG and 4.37±0.57 mg EQ for 100 mg of extract. A. dodoneifolius extract was given the best antioxidant activity on ABTS●+ radical inhibition method with 9279.19±416.37 µmol EAA/g. All these activities could partially justify the use of screened species in the traditional treatment of hepatitis.

The Ethnobotanical Investigation, Phytochemistry and Antioxidant Activity of a Medicinal Plant Recipe Directed against Candida albicans and Enterobacteria Stains Producing ESBL CTX-M-15 Type in Burkina Faso

“…This is found in the locality of Benin where Guinnin et al [29], by conducting an ethnobotanical study on medicinal plants used in the traditional treatment of viral hepatitis B and C obtained a predominance of 60.97% of men. After analyzing her results, we note that the low proportion observed among women could be due to the fact that in Africa, certain ritual practices are often associated [30]. In addition, women are generally taken up with household chores, which considerably limit their integration into the practice of traditional medicine.…”

Phytochemicals properties and antimicrobial activities of Carica papaya and Balanites aegyptiaca’ seeds aqueous infusion and decoction extracts

“…The antimicrobial activity of both plants seeds extracts included bacterial strains like Salmonella enteritidis, Salmonella tiphi, Bacillus cereus, Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Citrobacter amalonaticus, Sporolacto bacillus, Proteus mirabilis, Proteus vulgaris some virus as Vibrio vulnificus, Vibrio cholerae, human pathogen fungis like Candida albicans, Aspergillus flavus, Penicillium citrinum, Aspergillus flavus, phytopathogenic fungi like Rhizopus stolonifer, Fusarium spp. and Colletotrichum gloeosporioides 3,15,18,19 Previous surveys and studies also highlight an important and several uses of both C. papaya and B. aegyptiaca in Burkina Faso 20,21 but, their seeds phytochemicals content and antimicrobial analyses remain investigated 20,21 . This study then aims to appreciate phytochemicals content of local Carica papaya and Balanites aegyptiaca varieties seeds as well as the impact of extraction ISSN: 2250-1177…”