ETHNOBOTANICAL AND BIOLOGICAL ACTIVITIES OF Leptadenia pyrotechnica (Forssk.) Decne.: A REVIEW

Idrees, Saiba; Qureshi, Rahmatullah; Bibi, Yameen; Ishfaq, Aqsa; Khalid, Nadia; Iftikhar, Anam; Shabir, Anam; Riaz, Iqra; Ahmad, Saboon Nabeela

doi:10.21010/ajtcam.v13i4.13

Cited by 8 publications

(3 citation statements)

References 13 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These results indicated antidiabetic potential of L. pyrotechnica. Previously, in vivo antidiabetic studies disclosed that L. pyrotechnica extract induced dosage dependent reduction in blood glucose, [52] thus substantiated our results, and suggest the use of L. pyrotechnica extract in antidiabetic herbal formulations.…”

Section: Enzyme Inhibition Activitiessupporting

confidence: 88%

Chemodiversity, Biological Activities and Molecular Docking Studies ofLeptadenia pyrotechnica(Forssk.) Decne: A Comprehensive Approach to Validate Its Medicinal Use.

Saleem

Nazir

Raiz

et al. 2022

Chemistry & Biodiversity

View full text Add to dashboard Cite

Leptadenia pyrotechnica (Forssk.) Decne is growing in Cholistan desert, and is known for its laxative, analgesic, anabolic and astringent, antioxidant, anti‐inflammatory, antibacterial, antitumor, hypolipidemic and antiatherosclerotic properties. The present study disclosed the metabolic picture of L. pyrotechnica and validates its folk uses. LP‐H fraction constitute 25.79±0.11 mgGAE/g extract and 20.64±0.33 mgRE/g extract of phenolic and flavonoid content, respectively, followed by LP‐E (23.15±0.33 mgGAE/g extract and 19.40±0.13 mgRE/g extract), however, LP‐E exhibited the highest free radical scavenging (DPPH: 21.05±0.45mgTE/g and ABTS: 68.12±0.53 mgTE/g) and metal reducing (FRAP: 44.93±1.66, CUPRAC: 117.42±1.28 mgTE/g, respectively) activities. The total antioxidant capacity in Phosphomolybdenum assay (1.52±0.14 mmolTE/g) and ferrous ion chelating (11.57±0.29 mgEDTAE/g) activities were observed highest for LP‐H extract. In cholinesterase's inhibitory assays, the LP‐E and LP‐W extracts exhibited inhibitory values as 2.43 and 2.40±0.07 mgGALAE/g extract, respectively against AChE, while against BChE the LP‐H displayed the highest value as 5.98±0.44 mgGALAE/g extract. The LP‐H fraction also showed the highest inhibition potential (7.72±0.14 mmol ACAE/g and 0.55±0.01 mmol ACAE/g, respectively) against α‐glucosidase and α‐amylase enzymes, while, in tyrosinase inhibitory assay, all the fractions exhibited significant activities in the range of 59.35±0.29 to 55.18±0.49 mgKAE/g extract. RP‐UHPLC/MS analysis of LP‐M disclosed the presence of 57 metabolites of various classes. A multivariate analysis and molecular docking study was also carried out to establish relationships between the metabolites and the biological activities, which finally validate the use of L. pyrotechnica as herbal medicine or component nutraceutical, food and cosmetic industry.

show abstract

Section: Enzyme Inhibition Activitiessupporting

confidence: 88%

Chemodiversity, Biological Activities and Molecular Docking Studies ofLeptadenia pyrotechnica(Forssk.) Decne: A Comprehensive Approach to Validate Its Medicinal Use.

Saleem

Nazir

Raiz

et al. 2022

Chemistry & Biodiversity

View full text Add to dashboard Cite

show abstract

“…Anti-bacterial, anti-fungal, anti-cancer, anti-oxidant, anthelmintic, antidiabetic, hepatoprotective, anti-tumor, and wound healing effects have been discovered in this plant. Meanwhile, fatty acids, alkaloids, flavonoids, glycosides, and terpenes were found in the phytochemical investigation ( Idrees et al, 2016 , El-Demerdash et al, 1994 ).…”

Section: Plants Used For Dermatological Diseasesmentioning

confidence: 99%

Medicinal plants used for dermatological disorders among the people of the kingdom of Saudi Arabia: A narrative review

Almoshari

2022

Saudi Journal of Biological Sciences

View full text Add to dashboard Cite

“…The shrub has five-fold, short-stalked, greenish-yellow, hermaphrodite flowers with a double inflorescence and a diameter of 2 mm, which stands in axillary small cymose inflorescences. Fruits are 8–11 cm long, narrow, many-seeded, green, and follicular; when ripe, the seeds release pappus-tufted seeds into the wind ( Arbonnier, 2009 ; Idrees et al, 2016 ). During the months of August and January, the plant blooms and produces fruit.…”

Section: Introductionmentioning

confidence: 99%

Comparative morpho-anatomical study on Leptadenia pyrotechnica (Apocynaceae) growing in the hyper-arid and arid habitats of Saudi Arabia

Shaye¹

2023

PeerJ

View full text Add to dashboard Cite

The use of wild plants is considered to be an eco-friendly and promising natural resource. In sandy desert habitats, Leptadenia pyrotechnica flourishes as a xerophytic shrub with high biomass production. As a dominant shrub in the arid sand dune habitats of Saudi Arabia, Leptadenia pyrotechnica (Forssk.) Decne (Asclepiadaceae) is one of the most common xerophytes; the many medicinal uses of this plant include treating allergies, productive coughs, abortions, diabetes, stomach disorders, fevers, kidney disorders, and stones. In such a distribution, morpho-anatomical characteristics, among other adaptive traits, play an important role. This study aims to characterize some morpho-anatomical adaptations of L. pyrotechnica in two stressful habitats: the hyper-arid inland sand dunes of the Empty Quarter (EQ) and the arid coastal sand dunes of Jazan. A morpho-anatomical analysis of plant stems and roots from both habitats was conducted using light microscopy (LM) and scanning electron microscopy (SEM). The outcomes indicated similar characteristics, a low surface-to-volume ratio (S/V), a thin boundary layer (δbl), an epidermis with many layers of hypodermis, bundles of sclerenchymatous cells around vascular tissue, and storage starch grains in ray parenchyma between xylem conduits. On the other hand, the L. pyrotechnica stem from the hyper-arid habitat of the Empty Quarter revealed more encrypted stomata, more elongated palisade cells, less calcium oxalate crystals with low Ca percentage, and a high vulnerability index of xylem vessels compared with the same traits of the stem from the Jazan coastal sand dunes habitat. Roots of L. pyrotechnica from both habitats revealed similar features of general anatomy. However, differences in specific anatomical traits were observed, especially in xylem vessel characters. The vulnerability index of root xylem vessels from the Empty Quarter habitat was more than that from the Jazan coastal sand dunes habitat. Furthermore, vestured bordered pits in root xylem walls were more abundant in the Empty Quarter habitat than in the Jazan coastal sand dunes habitat. As a result, these characteristics in the morpho-anatomy of L. pyrotechnica from both habitats provide practical adaptations to highly stressful conditions, along with specific anatomical traits relating to each habitat.

show abstract

ETHNOBOTANICAL AND BIOLOGICAL ACTIVITIES OF Leptadenia pyrotechnica (Forssk.) Decne.: A REVIEW

Cited by 8 publications

References 13 publications

Chemodiversity, Biological Activities and Molecular Docking Studies ofLeptadenia pyrotechnica(Forssk.) Decne: A Comprehensive Approach to Validate Its Medicinal Use.

Chemodiversity, Biological Activities and Molecular Docking Studies ofLeptadenia pyrotechnica(Forssk.) Decne: A Comprehensive Approach to Validate Its Medicinal Use.

Medicinal plants used for dermatological disorders among the people of the kingdom of Saudi Arabia: A narrative review

Comparative morpho-anatomical study on Leptadenia pyrotechnica (Apocynaceae) growing in the hyper-arid and arid habitats of Saudi Arabia

Contact Info

Product

Resources

About