Ethical problems associated with prenatal diagnosis

Kwiatkowski, Oskar; Wołoszyn, Filip

doi:10.17219/pzp/114279

Cited by 1 publication

(1 citation statement)

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“…Intrauterine fetal imaging creates the possibility of early detection of most developmental defects, which translates to an increase in the success rate of intrauterine treatment or surgical intervention directly after birth. Apart from that, an increase in the survival rate or complete recovery of fetuses with a congenital defect is possible thanks to specialist, comprehensive care facilities of the highest referral level [27,28].…”

Section: Prenatal Diagnosticmentioning

confidence: 99%

Evaluation of the Risk of Birth Defects Related to the Use of Assisted Reproductive Technology: An Updated Systematic Review

Serafin¹,

Grabarek²,

Boroń³

et al. 2022

IJERPH

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Fertility problems constitute a serious medical, social, and demographic problem. With this review, we aim to critically appraise and evaluate the existing literature surrounding the risk of birth defects in offspring conceived using techniques based on assisted reproductive technology (ART). Based on searches of the literature in PubMed and ScienceDirect, we obtained a total of 2,003,275 works related to the topic. Ultimately, 11 original papers published in the last 10 years qualified for inclusion in the study. Based on five studies included in this analysis, it was shown that ART significantly increases the risk of congenital malformations in associated newborns. Due to the specifics of given studies, as well as potential confounding risk factors, this influence cannot be ignored. Therefore, considering the information contained in the articles included in this systematic review, it was determined that the risk of birth defects is not directly related to the use of ART itself but also depends on the age of partners, causes of infertility, comorbidities, and the number of fetuses during a pregnancy, as well as many other factors not covered in the literature. It is thus necessary to impress upon infertile couples who wish to have offspring that the use of ART is not risk-free but that the benefits outweigh the risks. Further education in this field, as well as social understanding, is also required.

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Section: Prenatal Diagnosticmentioning

confidence: 99%