Abstract:This PhD thesis summarizes the results obtained during the PhD program of the author. The main project consisted in structural studies of β-mannosidase from Trichoderma reesei and rabbit muscle Triose phosphate isomerase (TIM). Protein Crystallography and Small-Angle X-ray Scattering have been the mostly used techniques. The main results are the low resolution structure and a putative fold of β-mannosidase and three cristallographic TIM structures, determined in two crystal forms and different temperatures. On… Show more
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