Estudo da transmissão da leishmaniose tegumentar americana no Distrito Federal

Sampaio, Raimunda Nonata Ribeiro; Gonçalves, Marianne de Castro; Leite, Viviane Alves; França, Bruna Valle; Santos, Gilcilene Maria dos; Carvalho, Maria do Socorro Laurentino de; Tauil, Pedro Luíz

doi:10.1590/s0037-86822009000600015

Cited by 19 publications

(19 citation statements)

References 6 publications

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“…This case profile is like those observed in a previous epidemiological study conducted in the state [15], which observed that most cases occured in people between 31.6 to 34.5 years old [18,19]. The results also demonstrate a predominance of single CL lesions, which is in accordance with other studies conducted in the Amazon [19,20] and Pará [21].…”

Section: Discussionsupporting

confidence: 91%

Diagnosis and identification of Leishmania species in patients with cutaneous leishmaniasis in the state of Roraima, Brazil's Amazon Region

et al. 2021

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Background Cutaneous leishmaniasis (CL) is an endemic disease in Brazil that is highly prevalent in the northern region of the country. Although there is a continuous and growing number of cases registered in the state of Roraima, there is limited information regarding the species of Leishmania that affect the human population. In this study, we aimed to characterize which Leishmania species cause human disease in those presenting with cutaneous leishmaniasis in endemic areas of the State of Roraima. Methods We conducted a prospective surveillance study between 2016 to 2018 in health centers located in the State of Roraima, Brazil. Participants with clinical suspicion of CL were enrolled and provided lesion samples for parasitological detection by microscopy. A subset of the samples was tested by polymerase chain reaction and sequencing of the internal transcribed spacer 1 (ITS-1 PCR) for molecular species identification. Results A total of 262 participants were enrolled in this study. Of those, 129 (49.27%) were positive by parasitological examination. Most positive subjects (81.58%) were male, and most cases presented a single lesion (80.26%). ITS-1 PCR and sequencing on a subset of 76 samples allowed us to detect nine different species of Leishmania: L. (V.) braziliensis, L (V.) panamensis, L. (V.) guyanensis, L. (V.) naiffi, L. (V.) shawi, L.(V.) utingensis, L. (V.) lindenbergi, L. (L.) amazonensis and L. (L.) mexicana. Conclusions Our study provides the first assessment of circulating species of Leishmania in the State of Roraima, Brazil, and shows the high diversity in this region. This study opens the path for further research on the transmission of leishmaniasis in the northernmost Brazilian State including vector and reservoir surveillance as well as for intensification of investigation and control activities against CL in the region.

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Section: Discussionsupporting

confidence: 91%

Diagnosis and identification of Leishmania species in patients with cutaneous leishmaniasis in the state of Roraima, Brazil's Amazon Region

et al. 2021

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“…The mean abundance recorded in pigsties and houses was positively associated between these sites for Lu. Whitmani , as it was already described [67, 72]. The species is anthropophilic but also an opportunistic feeder, and so the pigsties and hen houses could provide blood, shelter, and breeding places for this vector [73–75].…”

Section: Resultsmentioning

confidence: 99%

Distribution and Abundance of Phlebotominae, Vectors of Leishmaniasis, in Argentina: Spatial and Temporal Analysis at Different Scales

Quintana

Fernández

Salomón

2012

Journal of Tropical Medicine

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The spatial-temporal analysis of the abundance of insects, vectors of tegumentary leishmaniasis (TL) and visceral leishmaniasis (VL), was performed in Argentina using spatial-temporal increasing scales. In the microscale (microfocal), the effect of the primary vegetation-crop interface in vector abundance was observed, and also how the shelters, food sources, and other environmental characteristics contribute to habitat microheterogeneity and so to a microheterogeneous vector distribution. In the mesoscale (locality or epidemic focus), the results from different foci of TL (rural and periurban) and VL (urban) suggested a metapopulation structure determined partially by quantifiable habitat variables that could explain the increase of risk associated to an increase of vector-human contact due to climatic or anthropogenic changes. In the macroscale (regional), captures of vectors and records of human cases allowed the construction of risk maps and predictive models of vector distribution. In conclusion, in order to obtain valid results transferrable to control programs from spatial studies, special attention should be paid in order to assure the consistency between the spatial scales of the hypotheses, data, and analytical tools of each experimental or descriptive design.

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“…In the correspondence analysis, some associations between disease in pregnant women and children younger than 1-year-old and indigenous/yellow ethnicity was found. This might explain the higher susceptibility of these populations to ATL and can be linked to characteristics related to exposure to the vector and vector adaptation to the peri and/or intra-domestic areas [28].…”

Section: Discussionmentioning

confidence: 99%

Profile of American tegumentary leishmaniasis in transmission areas in the state of Minas Gerais, Brazil, from 2007 to 2017

et al. 2020

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Background: American tegumentary leishmaniasis (ATL) is a widespread anthropozoonosis caused by protozoa of the genus Leishmania and is considered a serious public health problem. The aim of this study was to provide a descriptive analysis of confirmed ATL cases and evaluate the spatial distribution of ATL in high-risk transmission areas from the state of Minas Gerais, Brazil. Methods: An ecological, analytical, and retrospective study of the confirmed cases of ATL in Minas Gerais from 2007 to 2017 was conducted. To characterize these cases, multiple correspondence analysis and georeferencing of the ATL prevalence rates in the municipalities were conducted based on variables obtained at Sistema Nacional de Agravos de Notificação and Instituto Brasileiro de Geografia e Estatística databases. Results: There were 13,025 confirmed cases of ATL from 74.4% (635) municipalities of Minas Gerais, corresponding to a prevalence rate of 66.5 cases for every 100,000 inhabitants. Males aged 20 to 59 years and individuals who attended elementary school were most affected with ATL. Multiple correspondence analysis presented an accumulated qui-squared value of 44.74%, proving that there was a relationship between the variables, including ethnicity, age, pregnancy status, zone of infection, and number of cases. Conclusion: We confirmed that ATL is endemic to Minas Gerais, and there is high risk of infection within the municipalities due to a high rate of parasite transmission. The occurrence of infection in children, pregnant women, and the indigenous population demonstrates the need for the government to expand social policies aimed at vulnerable groups.

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Estudo da transmissão da leishmaniose tegumentar americana no Distrito Federal

Cited by 19 publications

References 6 publications

Diagnosis and identification of Leishmania species in patients with cutaneous leishmaniasis in the state of Roraima, Brazil's Amazon Region

Diagnosis and identification of Leishmania species in patients with cutaneous leishmaniasis in the state of Roraima, Brazil's Amazon Region

Distribution and Abundance of Phlebotominae, Vectors of Leishmaniasis, in Argentina: Spatial and Temporal Analysis at Different Scales

Profile of American tegumentary leishmaniasis in transmission areas in the state of Minas Gerais, Brazil, from 2007 to 2017

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