Estudo comparativo entre o pré-condicionamento isquêmico e a drenagem liquórica como métodos de proteção medular em cães

Benício, Anderson; Moreira, Luíz Felipe Pinho; Mônaco, Bernardo Assumpção de; Castelli, Jussara Bianchi; Mingrone, Larissa Eckmann; Na, Stolf

doi:10.1590/s0102-76382007000100007

Cited by 8 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…lumbar drains opened just before cross clamping) [ Table 2 ]. [ 3 ] At 7 postoperative days, the Tarlov neurological scores were significantly higher for the animals receiving CSFD, and they demonstrated faster/fuller recovery of adverse SEP changes.…”

Section: Methodsmentioning

confidence: 99%

Cerebrospinal fluid drains reduce risk of spinal cord injury for thoracic/thoracoabdominal aneurysm surgery: A review

Epstein¹

2018

Surg Neurol Int

View full text Add to dashboard Cite

Background:The risk of spinal cord injury (SCI) due to decreased cord perfusion following thoracic/thoracoabdominal aneurysm surgery (T/TL-AAA) and thoracic endovascular aneurysm repair (TEVAR) ranges up to 20%. For decades, therefore, many vascular surgeons have utilized cerebrospinal fluid drainage (CSFD) to decrease intraspinal pressure and increase blood flow to the spinal cord, thus reducing the risk of SCI/ischemia.Methods:Multiple studies previously recommend utilizing CSFD following T/TL-AAA/TEVAR surgery to treat SCI by increasing spinal cord blood flow. Now, however, CSFD (keeping lumbar pressures at 5–12 mmHg) is largely utilized prophylactically/preoperatively to avert SCI along with other modalities; avoiding hypotension (mean arterial pressures >80–90 mmHG), inducing hypothermia, utilizing left heart bypass, and employing intraoperative neural monitoring [somatosensory (SEP) or motor evoked (MEP) potentials]. In addition, preoperative magnetic resonance angiography (MRA) and computed tomographic angiography (CTA) scans identify the artery of Adamkiewicz to determine its location, and when/whether reimplantation/reattachment of this critical artery and or other major segmental/lumbar arterial feeders are warranted.Results:Utilizing CSFD for 15–72 postoperative hours in T/TL-AAA/TEVAR surgery has reduced the risks of SCI from a maximum of 20% to a minimum of 2.3%. The major complications of CSFD include; spinal and cranial epidural/subdural hematomas, VI nerve palsies, retained catheters, meningitis/infection, and spinal headaches.Conclusions:By increasing blood flow to the spinal cord during/after T/TL-AAA/TEVAR surgery, CSFD reduces the incidence of permanent SCI from, up to 10-20% down to down to 2.3-10%. Nevertheless, major complications, including spinal/cranial subdural hematomas, still occur.

show abstract

Section: Methodsmentioning

confidence: 99%

Cerebrospinal fluid drains reduce risk of spinal cord injury for thoracic/thoracoabdominal aneurysm surgery: A review

Epstein¹

2018

Surg Neurol Int

View full text Add to dashboard Cite

show abstract

“…Saba et al39 describe the total absence of neuroprotective effects of diltiazem in rabbits with occluded aorta. Neuroprotective effects of diltiazen, Benício et al40 compared ischemic preconditioning and cerebrospinal fluid drainage as methods of spinal cord protection in dogs and found that cerebrospinal fluid drainage and immediate ischemic preconditioning seem to protect the spinal cord during descending thoracic aorta cross-clamping. Nevertheless, spinal cord protection seems to be more significant with cerebrospinal fluid drainage.…”

Section: Neurologymentioning

confidence: 99%

Recent Trends in Brazilian Medical Research. An Overview

Rocha-e-Silva¹

2009

Clinics

View full text Add to dashboard Cite

This article reviews 69 original research articles published in 6 Brazilian Medical Journals recently incorporated into the Institute for Scientific Information Journal of Citation Reports, with a view of making them comprehensively available to the readership of CLINICS within a subject category division. We expect this review to increase the visibility of a wide specter of original Brazilian research which may otherwise remain relatively unseen by the interested readershi

show abstract

Spinal Cord Protection Strategies

Augoustides

2010

Anesthesia and Perioperative Care for Aortic Surgery

View full text Add to dashboard Cite

Estudo comparativo entre o pré-condicionamento isquêmico e a drenagem liquórica como métodos de proteção medular em cães

Abstract: Cerebrospinal fluid drainage and immediate ischemic preconditioning seems to protect the spinal cord during descending thoracic aorta cross-clamping. Nevertheless, the obtained level of spinal cord protection seems to be more significant with cerebrospinal fluid drainage.

Cited by 8 publications

References 27 publications

Cerebrospinal fluid drains reduce risk of spinal cord injury for thoracic/thoracoabdominal aneurysm surgery: A review

Cerebrospinal fluid drains reduce risk of spinal cord injury for thoracic/thoracoabdominal aneurysm surgery: A review

Recent Trends in Brazilian Medical Research. An Overview

Spinal Cord Protection Strategies

Contact Info

Product

Resources

About