Estimation of turbulent shear stresses in pulsatile flow immediately downstream of two artificial aortic valves in vitro

Nygaard, Hans; Giersiepen, M; Hasenkam, J. Michael; Westphal, D.; Paulsen, Peter Kildeberg; Reul, H.

doi:10.1016/0021-9290(90)90380-l

Cited by 31 publications

(9 citation statements)

References 14 publications

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“…These values are much lower than those reported in the literature, 22 where the calculated RBDI values for both the Hancock aortic porcine valve (HAPO) and the Ionescu-Shiley pericardial standard valve (ISPS) were about 1.8. These values are much lower than those reported in the literature, 22 where the calculated RBDI values for both the Hancock aortic porcine valve (HAPO) and the Ionescu-Shiley pericardial standard valve (ISPS) were about 1.8.…”

Section: Computational Resultscontrasting

confidence: 55%

Relative blood damage index of the jellyfish valve and the Bjork-Shiley tilting-disk valve

1999

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Determination of the potential for blood cell damage induced by artificial heart valves is essential in deciding the suitability of the valve for clinical use. Both the magnitude and the duration of the shear stress influence the onset and severity of the damage to the constituents of blood. In this study, in vitro shear stress measurements of the mitral jellyfish and Bjork-Shiley tilting-disk (mono) prosthetic valves under physiological pulsatile flow conditions were conducted. The data indicate that elevated levels of shear stress occurred mainly 1D downstream from both valves. With the aid of a mathematical model and using the elevated shear stress data, the relative release of hemoglobin by damaged red blood cells and of lactate dehydrogenase by platelets was computed for both valves. For the operating conditions examined, the jellyfish valve was found to cause the least damage to blood, with a relative blood damage index of 0.27 against a value of 0.47 for the Bjork-Shiley valve.

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Section: Computational Resultscontrasting

confidence: 55%

Relative blood damage index of the jellyfish valve and the Bjork-Shiley tilting-disk valve

1999

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“…Therefore, a more realistic setup involves pulsatile flow to create a range of random or irregular perturbations of velocities in time and space. Transient and turbulent flows in vivo can occur over a wide range of scales with an energy spectrum extending from a few Hz up to a few kHz .…”

mentioning

confidence: 99%

Mapping mean and fluctuating velocities by Bayesian multipoint MR velocity encoding‐validation against 3D particle tracking velocimetry

Knobloch

Binter

Gülan

et al. 2013

Magnetic Resonance in Med

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“…Nevertheless, the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study confirmed that atherosclerosis development occurs at an early age (49,50) and it is worthwhile to have ready a noninvasive detection method to track serious cases starting at an early age. MR visualization and quantification of flow patterns may also have value for evaluation and follow-up of vascular interventional procedures, given the present use of Doppler ultrasound in assessing vascular interventional complications (51)(52)(53)(54)(55)(56), and the importance of flow patterns in mediating the anastornotic endothelial response (57).…”

mentioning

confidence: 99%

Visualizing blood flow patterns using streamlines, arrows, and particle paths

Buonocore

1998

Magnetic Resonance in Med

165

140

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A customized computer program (MRIView) is described for visualizing and quantifying complex blood flow patterns in major vessels, using nongated and cardiac-gated three-dimensional (3D) velocity data obtained with MR velocity-encoded phase pulse sequences. Streamlines, arrows, and particle paths (collectively referred to as "paths") can be computed interactively, using both forward and backward time integration of the velocity field. The program provides interactive cross-sectional and 3D perspective visualization of the paths, with quantification and statistical analysis of average speed, through-plane velocity, cross-sectional area, and flow. Normal flow patterns in the carotid artery, basilar artery tip, ascending aorta, coronary arteries, descending aorta, and renal arteries, as well as abnormal flow patterns in basilar tip aneurysms, have been investigated. The program revealed flow patterns in these regions with features that are well known from Doppler ultrasound and other features that have not been reported previously. The association between specific abnormal flow patterns and development of atherosclerosis suggests that particle paths can be used to assess risk of plaque formation and progression, as well as to evaluate flow dynamics and vascular patency before and after vascular interventions.

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Estimation of turbulent shear stresses in pulsatile flow immediately downstream of two artificial aortic valves in vitro

Cited by 31 publications

References 14 publications

Relative blood damage index of the jellyfish valve and the Bjork-Shiley tilting-disk valve

Relative blood damage index of the jellyfish valve and the Bjork-Shiley tilting-disk valve

Mapping mean and fluctuating velocities by Bayesian multipoint MR velocity encoding‐validation against 3D particle tracking velocimetry

Visualizing blood flow patterns using streamlines, arrows, and particle paths

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