Estimation of Total Burden of Bladder Cancer in Brazil – An Economic and Clinical Approach

Abstract

Impairment -General Health questionnaire), multiplied by the Brazilian GDP per capita. For DC estimation, patients were identifying by ICD-10 code and procedures for BC treatment were obtained from national databases (Inpatient Information System, SIH/SUS and Outpatient Information System, SIA/SUS). The clinical impact of BC was analyzed by Disability Adjusted Life Years (DALYs). Years of life lost (YLL) was calculated based on the life expectancy (Brazilian Institute of Geography and Statistics) and BC mortality (SIM/DATASUS). Age-weighting and 5% discount rate were used. Years lived with disability (YLD) were calculated through an incidence perspective based on disability weights presented on Global Burden of Disease Study (2013) and incidence from Brazilian National Institute of Cancer. All analysis was based on 2014 data. ReSultS: In 2014, BC resulted in a loss of 27,738 years due to the premature death and 12,402 due to disabilities, resulting in 40,140 DALYs. Direct cost attribute to BC treatment was US$29,879,165, whereas indirect cost was estimation was of US$ 76,996,523. ConCluSionS: Despite the relative low incidence and age of patients affected, BC results in a relevant clinical and economic burden to the Brazilian society. The development of strategies related to prevention and early diagnosis is essential.

Bladder cancer trends and mortality in the brazilian public health system

“…Despite having a relatively low incidence, clinical characteristics of this neoplasms results in a relevant social and economic burden to Brazilian government. In 2014 alone, 27.738 life years were lost due to BC deaths, US$ 29.879.165 were directly spent with BC treatment and an indirect loss of US$76.996.523 was estimated (6).…”

Mortality after radical cystectomy is strongly related to the institution's volume of surgeries

“…(12) In Brazil, it is estimated 7.23 new cases per 100 thousand men and 2.80 per 100 thousand women, resulting in a relevant social and economic burden to the Brazilian government. (13)(14)(15) From 2008 to 2017, there were 8,925 open surgeries for BC in Brazil, with a mortality rate of 7.5%. (14) São Paulo is the richest and most populated state of Brazil.…”

“…No Brasil, estimam-se 7,23 novos casos por 100 mil homens e 2,80 por 100 mil mulheres, resultando em um ônus social e econômico relevante para o governo brasileiro. ( 13 – 15 ) De 2008 a 2017, ocorreram 8.925 cirurgias abertas para CB no Brasil, com taxa de mortalidade de 7,5%. ( 14 ) São Paulo é o estado mais rico e mais populoso do Brasil.…”