Estimation of Right Ventricular Diastolic Function in Patients With Ischemic Heart Disease in Different Age Groups

Gajfulin, R. A.; Sumin, А. N.; Arhipov, O. G.

doi:10.20996/1819-6446-2016-12-3-277-284

Cited by 1 publication

(1 citation statement)

References 24 publications

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“…An investigation by Fenster et al 15 demonstrated that diastolic dysfunction was able to independently influence exercise tolerance in subjects with chronic obstructive pulmonary disease. Gajfulin et al 16 evaluated diastolic dysfunction in ischemic heart disease and found an increase in A TV and a reduction in the E/A TV ratio and e'/a' TV among their study population. Some previous investigations on patients with dilated or ischemic cardiomyopathy, pulmonary hypertension, and congenital heart disorder have validated the role of E/e' TV in predicting mortality and readmissions 17‐19 .…”

Section: Discussionmentioning

confidence: 95%

Presence and prognostic value of ventricular diastolic function in arrhythmogenic right ventricular cardiomyopathy

et al. 2020

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Introduction Limited data exist regarding the presence and importance of diastolic parameters in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). We sought to evaluate RV diastolic parameters and echo‐based diastolic predictors of major adverse cardiovascular events (MACE). Method 48 patients with a definitive diagnosis of ARVC were included and followed for 6‐18 months. A comprehensive standard two‐dimensional (2D) transthoracic echocardiography (TTE) with precise evaluation of systolic and diastolic indices of both ventricles was done. RV isovolumetric relaxation time (IVRT), RV myocardial performance index (MPI), and right atrial (RA) volume were evaluated. Results 48 patients (mean age = 38.5 ± 14 years; 79.2% male) were enrolled. 27.3% had grade I, 68.2% had grade II, and 4.5% had grade III RV diastolic dysfunction. In 12‐month follow‐up, 12 patients (25%, with mean RV3DEF = 24.8 ± 9%) experienced MACE and required hospitalization: ventricular tachyarrhythmia in 7 patients (14.6%), RV clot in 2 subjects (4.2%), and right‐sided failure in 3 cases (6.3%). In logistic regression analysis, tissue Doppler velocity of tricuspid annulus (e' TV) (P = .02, OR = 0.581, CI = 0.368‐0.917), peak E mitral valve (P = .043, OR = 0.95, CI = 0.913‐0.999), tissue Doppler velocity of septal e' (P = .052, OR = 0.733, CI = 0.536‐1.003), and MPI (P = .009, OR = 95, CI = 3.083‐2942) were powerful predictors of MACE. Conclusion In our study, RV diastolic function parameters including e' TV and e′ MV, RA volume and area, and RV MPI were powerful predictors of MACE and may be considered during the baseline and follow‐up of the ARVC patients.

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Section: Discussionmentioning

confidence: 95%