Estimation of Lung Tissue Dose from the Inhalation of Radon and Daughters

Altshuler, Bernard; Nelson, Norton; Kuschner, Marvin

doi:10.1097/00004032-196412000-00035

Cited by 91 publications

(31 citation statements)

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“…When the mucous sheath gets thicker, fewer a-particles are able to penetrate to the basal cells of the epithelium from which the cancer develops (82). An increase in thickness of the mucous layer of only about 10 pm would decrease the dose to the epithelium by some 50% (83,84). Furthermore, the clearance of deposited particles carrying radon decay products may also be influenced by smoking with consequences for the ultimate radiation dose delivered to the epithelium.…”

Section: The Combined Effect Of Smoking and Radonmentioning

confidence: 99%

Cancer Risks from Exposure to Radon in Homes

Axelson¹

1995

Environmental Health Perspectives

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Exposure to radon and its decay products in mines is a well recognized risk of lung cancer in miners. A large number of epidemiologic studies from various countries are quite consistent in this respect even it the magnitude of the risk differs according to exposure levels. Indoor radon became a concern in the 1 970s and about a dozen studies have been conducted since 1979, mainly of the case-control design. From first being of a simple pilot character, the designs have become increasingly sophisticated, especially with regard to exposure assessment. Crude exposure estimates based on type of house, building material and geological features have been supplemented or replaced by quite extensive measurements. Still, exposure assessment remains a difficult and uncertain issue in these studies, most of which indicate a lung cancer risk from indoor radon. Also a recent large scale study has confirmed a lung cancer risk from indoor radon. More recently there are also some studies, mainly of the correlation type, suggesting other cancers also to be related to indoor radon, especially leukemia, kidney cancer, and malignant melanoma, and some other cancers as well. The data are less consistent and much more uncertain than for indoor radon and lung cancer, however; and there is no clear support from studies of miners in this respect. -Environ Health Perspect 103 (Suppl 2:37-43 (1995)

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Section: The Combined Effect Of Smoking and Radonmentioning

confidence: 99%

Cancer Risks from Exposure to Radon in Homes

Axelson¹

1995

Environmental Health Perspectives

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“…Altshuler et al (46) and Jacobi (47) chose the respiratory tract model of Findeisen (60) in its improved form by Landahl (61). A partial description of the Landahl model is given in Table 6.…”

Section: Limitations In Deposition Modelsmentioning

confidence: 99%

“…Altshuler et al (46) (33) and Holleman (44) for the Haque and Collinson (48) and Altshuler et al (46) calculations. We may conclude that although different methods of dose calculations were used, the main reasons for the differences displayed in Table 4 L.…”

Section: Critical Tissuementioning

confidence: 99%

Environmental Radiation and the Lung

Hamrick¹,

Walsh²

1974

Environmental Health Perspectives

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“…Les premiers modèles dosimétriques pulmonaires décrivant l'inhalation, le dépôt et la rétention des descendants du radon apparaissent en 1964 (Altschuler et al, 1964 ;Jacobi, 1964). En 1966, est publié le modèle du Task Group on Lung Dynamics (1966).…”

Section: Introductionunclassified

Les incertitudes sur la dose délivrée aux voies respiratoires après exposition au radon

Monchaux

Massé

1999

Radioprotection

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Uncertainties on the dose delivered to the respiratory tract after radon exposure.Irradiation of the different tissues of the respiratory tract by radionuclides of natural origin is mainly related with exposure to radon and its short-lived decay products. The dose to the different regions of the lung arising from inhalation of radon progeny C~M & be measured directly. It must be calculated using models which îake into account the various processes involved: inhalation, deposition, clearance and decay of radon progeny in the ainvays of the lung. This paper reviews the main historical dosimetric models and the different morphometric models used for dosimetric purpose. The new Human Respiratory ïjact Mode1 for RadWlogicaIProtectn (ICRP) and the influence of the localisation and distribution of target cells and that of depasition and clearance parameters on dose calculations are described. A comparison between the different dosimetric models and the influence of modelling variables on the uncertainties of dose calculations are addresseà.

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Estimation of Lung Tissue Dose from the Inhalation of Radon and Daughters

Cited by 91 publications

References 0 publications

Cancer Risks from Exposure to Radon in Homes

Cancer Risks from Exposure to Radon in Homes

Environmental Radiation and the Lung

Les incertitudes sur la dose délivrée aux voies respiratoires après exposition au radon

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