Estimation for Akshaya Failure Model with Competing Risks under Progressive Censoring Scheme with Analyzing of Thymic Lymphoma of Mice Application

Abstract

In several experiments of survival analysis, the cause of death or failure of any subject may be characterized by more than one cause. Since the cause of failure may be dependent or independent, in this work, we discuss the competing risk lifetime model under progressive type-II censored where the removal follows a binomial distribution. We consider the Akshaya lifetime failure model under independent causes and the number of subjects removed at every failure time when the removal follows the binomial distribution with known parameters. The classical and Bayesian approaches are used to account for the point and interval estimation procedures for parameters and parametric functions. The Bayes estimate is obtained by using the Markov Chain Monte Carlo (MCMC) method under symmetric and asymmetric loss functions. We apply the Metropolis–Hasting algorithm to generate MCMC samples from the posterior density function. A simulated data set is applied to diagnose the performance of the two techniques applied here. The data represented the survival times of mice kept in a conventional germ-free environment, all of which were exposed to a fixed dose of radiation at the age of 5 to 6 weeks, which was used as a practice for the model discussed. There are 3 causes of death. In group 1, we considered thymic lymphoma to be the first cause and other causes to be the second. On the base of mice data, the survival mean time (cumulative incidence function) of mice of the second cause is higher than the first cause.

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