Estimating age-stratified WAIS-R IQS from scores on the raven's standard progressive matrices

O'Leary, Una-Marie; Rusch, Kathleen M.; Guastello, Stephen J.

doi:10.1002/1097-4679(199103)47:2<277::aid-jclp2270470215>3.0.co;2-i

Cited by 50 publications

(29 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Four samples reported data on Spearman's g , and four samples used IQ scores. One sample(14) reported IQ scores derived from the Raven's Progressive Matrix test (RPM), which measures non-verbal cognitive ability and is highly correlated with WAIS full-scale IQ (r = 0.74)(33). Another sample(18) reported estimated IQ scores converted from a verbal intelligence scale (Mehrfachwahl-Wortschatz-Intelligenztest; MWT-B).…”

Section: Resultsmentioning

confidence: 99%

Meta-Analysis of Genetic Variation in DTNBP1 and General Cognitive Ability

Zhang

Burdick

Lencz

et al. 2010

Biological Psychiatry

View full text Add to dashboard Cite

Background The human dystrobrevin-binding protein 1 (DTNBP1) gene has been linked to risk for schizophrenia. Recent studies indicate that several single nucleotide polymorphisms (SNPs) in the DTNBP1 gene may also influence general cognitive ability in both schizophrenic patients and healthy controls. We examined the relationship between DTNBP1 SNPs and general cognitive ability in non-psychiatric healthy samples via meta-analysis. Methods Medline search (12/31/2009) yielded 11 articles examining DTNBP1 variation and general cognitive ability, of which 8 studies had data available encompassing 10 independent cohorts (total n=7,592). The phenotype was defined as either the first principal component score from multiple neuropsychological tests (Spearman's g) or full scale IQ. Meta-analyses were conducted for 9 SNPs for which cognitive data were available from at least 3 cohorts. For each SNP in each cohort, effect size (ES) was computed between major allele homozygotes and minor allele carriers; ES was then pooled across studies using a random effect model. Results Pooled ES's from 2 of the 9 SNPs (rs1018381 and rs2619522) were -0.123 and -0.083, p's<0.01, respectively, suggesting that the minor allele carriers of these SNPs had lower cognitive ability scores than the major allele homozygotes. Results remained significant after examining heterogeneity among samples and potential publication biases. Other SNPs did not show significant effects on general cognitive ability. Conclusion Genetic variation in DTNBP1 modestly influences general cognitive ability. Further studies are needed to elucidate the biological mechanisms that may account for this relationship.

show abstract

Section: Resultsmentioning

confidence: 99%

Meta-Analysis of Genetic Variation in DTNBP1 and General Cognitive Ability

Zhang

Burdick

Lencz

et al. 2010

Biological Psychiatry

View full text Add to dashboard Cite

show abstract

“…General intelligence was estimated using the Standard Progressive Matrices 10. This study was carried out under the guidelines for the use of human participants established by the Institutional Review Board at Severance Mental Health Hospital, Yonsei University.…”

Section: Methodsmentioning

confidence: 99%

Disruption of Orbitofronto-Striatal Functional Connectivity Underlies Maladaptive Persistent Behaviors in Alcohol-Dependent Patients

Lee

et al. 2013

Psychiatry Investig

View full text Add to dashboard Cite

ObjectiveAlcohol dependence is characterized by persistent alcohol-seeking despite negative consequences. Previous studies suggest that maladaptive persistent behaviors reflect alcohol-induced brain changes that cause alterations in the cortico-striatal-limbic circuit.MethodsTwenty one alcohol dependent patients and 24 age-matched healthy controls performed a decision-making task during functional MRI. We defined the medial orbitofrontal cortex (mOFC) as a region-of-interest and performed seed-based functional connectivity analysis.ResultsHealthy controls were more flexible in adapting an alternative behavioral strategy, which correlated with stronger mOFC-dorsal striatum functional connectivity. In contrast, alcohol dependent patients persisted to the first established behavioral strategy. The mOFC-dorsal striatum functional connectivity was impaired in the alcohol-dependent patients, but increased in correlation with the duration of abstinence.ConclusionOur findings support that the disruption of the mOFC-striatal circuitry contribute to the maldaptive persistent behaviors in alcohol dependent patients.

show abstract

“…The Mini-Mental State Examination was used as a screen 9. The Raven’s Progressive Matrices tests, which require non-verbal ability, are the most popular 10. One of these, the Raven’s Coloured Progressive Matrices,11 was used.…”

Section: Methodsmentioning

confidence: 99%