Estimated incidence of influenza-virus-associated severe pneumonia in children in El Salvador, 2008–2010

Clara, Wilfrido; Armero, Julio; Rodríguez, David Sarias; Lozano, Celina de; Bonilla, Luis; Minaya, Percy; Chacón, Rafael Barrera; Jara, Jorge; Blanco, Natalia; Widdowson, Marc‐Alain; Bresee, Joseph S.; Xu, Xinyi; Klimov, Alexander; Azziz‐Baumgartner, Eduardo; Linares-Pérez, Nivaldo

doi:10.2471/blt.11.098202

Cited by 33 publications

(39 citation statements)

References 22 publications

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“…Costa Rica used similar methods6 and obtained comparable results. El Salvador and Nicaragua3, 4 estimated slightly higher rates than our results, whereas another study conducted in Guatemala5 estimated slightly lower rates. These differences could be explained by the use of active population‐based surveillance in these studies which may have resulted in increased referrals of case‐patients to the hospital.…”

Section: Discussioncontrasting

confidence: 89%

“…Influenza surveillance among SARI case‐patients was conducted in the study countries by sentinel hospitals and National Influenza Centers according to PAHO‐CDC 2006 generic protocol for influenza surveillance 3, 6. Laboratories tested respiratory samples using immunofluorescence and rtRT‐PCR3, 6 after systematically identifying a sample of SARI cases through routine clinical practice.…”

Section: Methodsmentioning

confidence: 99%

“…Laboratories tested respiratory samples using immunofluorescence and rtRT‐PCR3, 6 after systematically identifying a sample of SARI cases through routine clinical practice. We determined the age‐stratified percentage of samples from SARI case‐patients testing positive for influenza virus by dividing the number of positive by the total sampled each same month.…”

Section: Methodsmentioning

confidence: 99%

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Estimating the burden of influenza‐associated hospitalizations and deaths in Central America

Descalzo

Clara²,

Guzman

et al. 2016

Influenza Resp Viruses

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ObjectivesOur objective was to estimate the incidence of influenza‐associated hospitalizations and in‐hospital deaths in Central American Region.Design and settingWe used hospital discharge records, influenza surveillance virology data, and population projections collected from Costa Rica, El Salvador, Guatemala, Honduras, and Nicaragua to estimate influenza‐associated hospitalizations and in‐hospital deaths. We performed a meta‐analysis of influenza‐associated hospitalizations and in‐hospital deaths.Main outcome measuresThe highest annual incidence was observed among children aged <5 years (136 influenza‐associated hospitalizations per 100 000 persons).ResultsAnnually, 7 625–11 289 influenza‐associated hospitalizations and 352–594 deaths occurred in the subregion.ConclusionsOur results suggest that a substantive number of persons are annually hospitalized because of influenza. Health officials should estimate how many illnesses could be averted through increased influenza vaccination.

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Section: Discussioncontrasting

confidence: 89%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Estimating the burden of influenza‐associated hospitalizations and deaths in Central America

Descalzo

Clara²,

Guzman

et al. 2016

Influenza Resp Viruses

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“…For each age group, we multiplied the monthly number of SARI case-patients by the proportion of influenza-positive samples from SARI case-patients (Figure) and their 95% CI ( 9 ). …”

Section: The Studymentioning

confidence: 99%

Influenza-associated Hospitalizations and Deaths, Costa Rica, 2009–2012

Saborío¹,

Clara²,

García³

et al. 2014

Emerg. Infect. Dis.

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“…There are some strategies that allow for the estimation of influenza burden of disease using data from epidemiological surveillance when it is associated with the use of laboratory techniques for confirmation. In the Americas, several estimation analyses have been carried out using these methods, mainly in the United States, but also in Central America and the Caribbean 10, 11, 12, 13, 14, 15, 16, 17. In Chile, despite having a stable surveillance system with quality data, to date, no burden estimates have been made using these strategies.…”

Section: Introductionmentioning

confidence: 99%

Estimating the burden of influenza‐associated hospitalizations and deaths in Chile during 2012‐2014

Sotomayor

Fasce

Vergara

et al. 2018

Influenza Resp Viruses

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BackgroundInfluenza is a vaccine preventable disease that causes important morbidity and mortality worldwide. Estimating the burden of influenza disease is difficult. However, there are some methods based in surveillance data and laboratory testing that can be used for this purpose.ObjectivesEstimating the burden of serious illness from influenza by means of hospitalization and death records during the period between 2012 and 2014, and using information from Severe Acute Respiratory Illness (SARI) surveillance.MethodsTo estimate the Chilean rate of influenza‐associated hospitalizations and deaths, we applied the influenza positivity of respiratory samples tested in six SARI surveillance sentinel hospitals to the hospitalizations and deaths from the records with ICD‐10 codes from influenza and pneumonia.ResultsAnnually, 5320 people are hospitalized for influenza and 447 die for this cause. The annual influenza‐associated hospitalization rate for the period was 71.5/100 000 person‐year for <5 years old, 11.8/100 000 person‐year for people between 5 and 64 years old; and 156.0/100 000 person‐year for ≥65 years. The annual mortality rate for the period was 0.08/100 000 person‐year for <5 years; 0.3/100 000 person‐year for people between 5 and 64 years; and 22.8/100 000 person‐year for ≥65 years.ConclusionsThis is the first study of influenza burden in Chile. Every year an important quantity of hospitalizations and deaths result from influenza infection. In countries in temperate zones, it is important to know the burden of influenza in order to prepare the health care network and to assess preventive intervention currently in practice and the new ones to implementing.

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Estimated incidence of influenza-virus-associated severe pneumonia in children in El Salvador, 2008–2010

Cited by 33 publications

References 22 publications

Estimating the burden of influenza‐associated hospitalizations and deaths in Central America

Estimating the burden of influenza‐associated hospitalizations and deaths in Central America

Influenza-associated Hospitalizations and Deaths, Costa Rica, 2009–2012

Estimating the burden of influenza‐associated hospitalizations and deaths in Chile during 2012‐2014

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