Esthesioneuroblastoma, also called olfactory neuroblastoma, is a rare malignant tumor originating in the olfactory epithelium in the upper nasal cavity with intracranial extension and may also be associated with secondary sinus diseases. Esthesioneuroblastoma has been observed to cause death by distant metastasis or by invasion through the cribriform plate and secondary meningitis. It usually produces nasal obstruction, epistaxis and less commonly anosmia, headache and pain. We report a case of esthesioneuroblastoma in a 50-year-old female who reported with tooth pain as a presenting symptom.