2022
DOI: 10.21037/atm-22-4181
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Establishment and validation of an individualized nomogram for survival prediction of primary mediastinal germ cell tumors based on the SEER database

Abstract: Background: Primary mediastinal germ cell tumors (PMGCT) represent a rare but sometimes highly aggressive type of mediastinal tumors. The current prognostic models for PMGCT are insufficient. This study was undertaken to establish and validate an individualized nomogram for predicting the overall survival (OS) of patients with PMGCT. Methods: We conducted a retrospective analysis of patients with PMGCT diagnosed between 2000 and 2018 in the Surveillance, Epidemiology, and End Results (SEER) database in the Uni… Show more

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Cited by 2 publications
(2 citation statements)
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“…This prognostic classification system, however, is only based on univariate and multivariate analyses. By using the SEER database, age, stage, tumor size, histology type, radiation, CT, and surgery resection range were identified as independent factors and integrated to construct a nomogram for OS in patients with PMGCT 16 . However, no relevant prognostic model for the nonseminomatous PMGCTs has been established.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…This prognostic classification system, however, is only based on univariate and multivariate analyses. By using the SEER database, age, stage, tumor size, histology type, radiation, CT, and surgery resection range were identified as independent factors and integrated to construct a nomogram for OS in patients with PMGCT 16 . However, no relevant prognostic model for the nonseminomatous PMGCTs has been established.…”
Section: Discussionmentioning
confidence: 99%
“…More recently, Caso et al 4 investigated factors associated with overall survival (OS) and progression-free survival in patients with nonseminomatous PMGCTs but focused mainly on multidisciplinary treatment management. Qi et al 16 explored the prognostic variables of PMGCT patients in a large population-based study of the SEER database, but only involved demographics, pathological, and therapeutic information. Due to the lack of authoritative guidance,treatment strategies for nonseminomatous PMGCTs are still controversial.…”
Section: Introductionmentioning
confidence: 99%