Essential oils: From extraction to encapsulation

Asbahani, A. El; Miladi, Karim; Badri, Waisudin; Sala, M.; Addi, El Habib Ait; Casabianca, Hervé; Mousadik, Abdelhamid El; Hartmann, Daniel; Jilale, Abderrahim; Renaud, François; Elaı̈ssari, Abdelhamid

doi:10.1016/j.ijpharm.2014.12.069

Cited by 837 publications

(523 citation statements)

References 188 publications

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“…It was observed that a total solid higher than 27.1 g by 100 mL of emulsion gave the higher total retention of essential oil. These results are according to El Asbahani et al (2015), who showed that maltodextrin-gum arabic-xanthan gum blend is a good encapsulating material for essential oil; however, the content of these in the blend should be optimized.…”

Section: Retention Of Essential Oilsupporting

confidence: 54%

LEMONGRASS (Cymbopogon citratus (DC) Stapf) ESSENTIAL OIL ENCAPSULATION BY FREEZE-DRYING

Enciso¹

2018

Rev. Mex. Ing. Quim.

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The objective of this study was to determine the effect of different encapsulating agents (gum arabic (GA), maltodextrin (MD) and/or xanthan gum (XG) and two different freezing methods (slow and fast)) on the encapsulating efficiency of Cymbopogon citratus essential oil and on its release during storage. Retention of α− and β−citral, β−myrcene and linalool were determined by Gas Chromatography Mass Spectra (GC MS). Release of the encapsulated compounds was determined at 76% relative humidity and 30°C. The highest retention obtained was 78±9% for β−citral, 100±16% for α−citral, 81.6±5.8% for β−myrcene and 39.7±2.3% for linalool with the slow tested freezing protocol and a mixture of 50% GA, 40% MD, and 10% XG (volume). Kinetic release during storage was exponential and adequately fitted with Avrami´s model. Lemongrass essential oil can be encapsulated by freeze-drying using a mixture of gum arabic, maltodextrin and xanthan gum with a high retention of volatile compounds by using a slow freezing protocol. Keywords: Cymbopogon citratus, citral, myrcene, linalool, freeze-drying. ResumenEl objetivo de este trabajo fue determinar el efecto de diferentes mezclas de agentes encapsulantes (goma arábiga (GA), maltodextrina (MD) y/o goma xantana (GX) y dos diferentes métodos de congelamiento (lento y rápido)) sobre la eficiencia de encapsulamiento del aceite esencial de Cymbopogon citratus y evaluar su liberación durante el almacenamiento. La retención de α− y β−citral, β−mirceno y linalol se determinaron mediante cromatografía de gases con espectrometría de masas (CG EM). La liberación de los compuestos durante el almacenamiento se evaluó a 76% de humedad relativa y 30°C. Las retenciones más altas obtenidas fueron 78±9% para β−citral, 94±5.6% para α−citral, 81.6±5.8% para β−mirceno y 39.7±2.3% para linalol, utilizando congelación lenta y una mezcla de 50% GA, 40% MD y 10% GX (volumen). La cinética de liberación de compuestos durante el almacenamiento fue exponencial y ajustada con el modelo de Avrami. El aceite esencial de zacate limón puede ser encapsulado mediante liofilización usando una mezcla de goma arábiga, maltodextrina y goma xantana con una retención elevada de compuestos volátiles utilizando una congelación lenta.

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Section: Retention Of Essential Oilsupporting

confidence: 54%

LEMONGRASS (Cymbopogon citratus (DC) Stapf) ESSENTIAL OIL ENCAPSULATION BY FREEZE-DRYING

Enciso¹

2018

Rev. Mex. Ing. Quim.

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“…These oils have numerous biological activities, such as antioxidant, anti-inflammatory, anti-tumoral, fungicidal, bactericidal, and insecticidal activities, that make their use prominent in the pharmaceutical, food, perfumery and cosmetic industries [6].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity of the Essential Oil from <i>Hyptis carpinifolia</i> Benth

Camargo¹,

Batista²,

Souza³

et al. 2017

AJPS

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Essential oils are secondary metabolites whose biological properties have been studied with emphasis on antimicrobial activity. Hyptis carpinifolia Benth (Rosmaninho) is used in folk medicine in the fight against colds and rheumatism. The objective of this study was to evaluate the antimicrobial activity of the essential oil from H. carpinifolia. The essential oil was extracted by hydrodistillation using a modified Clevenger apparatus. The biological activity was determined using the Agar Cavity Diffusion technique to evaluate the effect of concentrations of 500, 250, 125, 62.5, 31.25, 15.62, 7.81 and 3.9

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“…The use of submicrometric colloidal nanocarriers such as nanoparticles (NP) lipid and polymeric, nanoemulsions (NE), microemulsions (ME), liposomes, and polymeric micelles is considered a promising system in the pharmaceutical field, because they have numerous advantages over traditional formulations such as: sustained release of the active element; solubilization of lipophilic molecules; use for different routes of administration; protection from chemical and enzymatic degradation of labile molecules; reduction of vegetable oils (VO) volatilization, side effects and dose (Mäder, Mehnert, 2005;Mehnert, Mäder, 2001;Gref, Couvreour, 2006;Couvreur, Vauthier, 2006;Panyam, Labhasetwar, 2003;Soppimath et al, 2001;Ai et al, 2011;Contri et al, 2012;Contri et al, 2014;Dimer et al, 2014;Severino et al, 2015;Frank et al, 2015;Asbahani et al, 2015). However, all systems differ thermodynamic stability, structure, chemical composition, efficiency encapsulation and types of application (Mäder, Mehnert, 2005;Ai et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…These factors combined with low topical permeation due to the poor aqueous solubility limits the display of VO as candidates for dermatological treatments (São Pedro et al, 2013). For this reason, nanoencapsulation has been used as an alternative to increase the stability, efficacy, solubility, sensory character, and also the controlled release of natural assets through techniques involving nanotechnology (Chanchal, Swarnlata, 2008;Daudt et al, 2013;Flores et al, 2013;Flores et al, 2015;Severino et al, 2015;Asbahani et al, 2015). This artifice allows the use of VO not only on the skin, but also in alternative routes of administration that include intravenous, oral and inhalatory forms (Roger et al, 2010;Thanki et al, 2013; Lai, Wang, Hanes, 2009;Kushwaha, Keshari, Rai, 2011;Singh et al, 2011).…”

mentioning

confidence: 99%

The use of Brazilian vegetable oils in nanoemulsions: an update on preparation and biological applications

Bajerski

Michels

Colomé

et al. 2016

Braz. J. Pharm. Sci.

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Vegetable oils present important pharmacological properties, which gained ground in the pharmaceutical field. Its encapsulation in nanoemulsions is considered a promising strategy to facilitate the applicability of these natural compounds and to potentiate the actions. These formulations offer several advantages for topical and systemic delivery of cosmetic and pharmaceutical agents including controlled droplet size, protection of the vegetable oil to photo, thermal and volatilization instability and ability to dissolve and stabilize lipophilic drugs. For these reasons, the aim of this review is to report on some characteristics, preparation methods, applications and especially analyze recent research available in the literature concerning the use of vegetable oils with therapeutic characteristics as lipid core in nanoemulsions, specially from Brazilian flora, such as babassu (Orbignya oleifera), aroeira (Schinus molle L.), andiroba (Carapa guaianiensis), casca-de-anta (Drimys brasiliensis Miers), sucupira (Pterodon emarginatus Vogel) and carqueja doce (Stenachaenium megapotamicum) oils.Uniterms: Plant oils/nanoemulsions/preparation. Plant oils/biological applications. INTRODUCTIONThe use of submicrometric colloidal nanocarriers such as nanoparticles (NP) lipid and polymeric, nanoemulsions (NE), microemulsions (ME), liposomes, and polymeric micelles is considered a promising system in the pharmaceutical field, because they have numerous advantages over traditional formulations such as: sustained release of the active element; solubilization of lipophilic molecules; use for different routes of administration; protection from chemical and enzymatic degradation of labile molecules; reduction of vegetable oils (VO) volatilization, side effects and dose (Mäder, Mehnert, 2005;Mehnert, Mäder, 2001;Gref, Couvreour, 2006;Couvreur, Vauthier, 2006; Panyam, Labhasetwar, 2003;Soppimath et al., 2001;Ai et al., 2011; Contri et al., 2012;Contri et al., 2014;Dimer et al., 2014;Severino et al., 2015;Frank et al., 2015;Asbahani et al., 2015). However, all systems differ thermodynamic stability, structure, chemical composition, efficiency encapsulation and types of application (Mäder, Mehnert, 2005;Ai et al., 2011).The development of suitable nanocarriers for pharmaceutical or cosmetic application requires the adequate selection of their adjuvants such as polymers for nanocapsules (NC), surfactants, and oils (Schaffazick et al., 2003;Alvarez-Román et al., 2001;Bouchemal et al., 2004;Friedrich et al., 2008). Recently, special attention has been given to the type of oily phase used as the core in the preparation of NE. VO has been preferred not only due to the concept that it is safe and biocompatible, but mainly because of the diversity of benefits, and the complex composition of fatty acids can exercise under the skin, protecting it against dehydration, solar radiation, inflammation, insect attack, microorganisms, and viruses (Tadros, Kessell, 2004;Bloise, 2003;Oyedeji, Okeke, 2010;Bakkali et. al., 2008;Harris, 2002; Contri et al, ...

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Essential oils: From extraction to encapsulation

Cited by 837 publications

References 188 publications

LEMONGRASS (Cymbopogon citratus (DC) Stapf) ESSENTIAL OIL ENCAPSULATION BY FREEZE-DRYING

LEMONGRASS (Cymbopogon citratus (DC) Stapf) ESSENTIAL OIL ENCAPSULATION BY FREEZE-DRYING

Antimicrobial Activity of the Essential Oil from <i>Hyptis carpinifolia</i> Benth

The use of Brazilian vegetable oils in nanoemulsions: an update on preparation and biological applications

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Essential oils: From extraction to encapsulation

Cited by 837 publications

References 188 publications

LEMONGRASS (Cymbopogon citratus (DC) Stapf) ESSENTIAL OIL ENCAPSULATION BY FREEZE-DRYING

LEMONGRASS (Cymbopogon citratus (DC) Stapf) ESSENTIAL OIL ENCAPSULATION BY FREEZE-DRYING

Antimicrobial Activity of the Essential Oil from &lt;i&gt;Hyptis carpinifolia&lt;/i&gt; Benth

The use of Brazilian vegetable oils in nanoemulsions: an update on preparation and biological applications

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Antimicrobial Activity of the Essential Oil from <i>Hyptis carpinifolia</i> Benth