Essential oil constituents of Illicium griffithii and its antimicrobial activity

Saraswathy, A; Shakila, R; Sm, Lavanya; A, Arunmozhidevi

doi:10.4103/0973-1296.66938

Cited by 10 publications

(5 citation statements)

References 8 publications

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“…They have the potential to be an effective solution for the problem of antibiotic resistance development. [ 7 17 18 19 ]…”

Section: Introductionmentioning

confidence: 99%

Investigation of effect of 1,8-cineole on antimicrobial activity of chlorhexidine gluconate

Simsek¹,

Duman²

2017

Phcog Res

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Background:Chlorhexidine belongs to a group of medicines called antiseptic antibacterial agents. Chlorhexidine is commonly used for the care and clean off the skin, hands, and wounds. In recent years, medicinal and aromatic plants have been used for prevention of disease, maintaining health, and improving disease in traditional and modern medicine as a medicament. According to recent research, cineole is the isolated active agent of eucalyptus oil and possesses antimicrobial activity. It was demonstrated that cineole could enhance the antimicrobial effects of the other antiseptics.Objective:The aim of this study was to investigate the efficacy of 1,8-cineole on the antimicrobial effect of chlorhexidine against some microorganisms.Materials and Methods:The effect of 1,8-cineole on antimicrobial activity of chlorhexidine gluconate (CHG) was tested using seven different microorganisms. In this study, CHG (128–0.125 mg/l) and cineole (512–2 g/l) were analyzed together and separately using checkerboard assay. Interactions between CHG and 1,8-cineole have been identified as synergistic, indifferent, or antagonistic.Results:Synergistic activity was demonstrated between CHG and 1,8-cineole against Staphylococcus aureus, methicillin-resistant S. aureus, Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, and Candida albicans. Indifferent interactions for these compounds were demonstrated against Pseudomonas aeruginosa.Conclusion:CHG antiseptic properties were found to be increased when CHG was used in combination with 1,8-cineole. In this way, CHG will reveal stronger effect against microorganisms.SUMMARY Cineole has increased the antimicrobial activity of chlorhexidine gluconate against all microorganisms except Pseudomonas aeruginosaIn topical application, using cineole in combination with chlorhexidine may be easier, eradicate certain resistant bacteria by increasing the antimicrobial efficacy. Abbreviation Used: CHG: Chlorhexidine gluconate, MRSA: Methicillin-resistant S. aureus, MHB: Mueller Hinton broth, SDB: Sabouraud dextrose broth, CFU: Colonyforming unit, FIC: Fractional inhibitory concentration, FICI: FIC index, EO: Eucalyptus oil.

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“…They have the potential to be an effective solution for the problem of antibiotic resistance development. [ 7 17 18 19 ]…”

Section: Introductionmentioning

confidence: 99%

Investigation of effect of 1,8-cineole on antimicrobial activity of chlorhexidine gluconate

Simsek¹,

Duman²

2017

Phcog Res

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“…On the other hand, some major components (such as α-pinene, γ-muurolene, caryophyllene oxide) have been detected in essential oils antimicrobial, antioxidant, and gastroprotective activities (Almeida et al, 2015;Saraswathy et al, 2010;Policegoudra et al, 2012).…”

Section: Resultsmentioning

confidence: 99%

Spermostatic activity of Eugenia brejoensis and Myroxylon peruiferum essential oils toward human spermatozoa

Nascimento¹,

Filho²,

Oliveira³

et al. 2018

J. Med. Plants Res.

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In this study, the in vitro spermostatic action, hemolytic action in combination of parabens of two essential oils (EOs) from Eugenia brejoensis Mazin (Myrtaceae, EbEO) and Myroxylon peruiferum L. (Fabaceae, MpEO) is reported, in addition to the first chemical characterization of MpEO. The EOs were obtained by hydrodistillation and characterized by gas chromatography-mass spectrometry (GC-MS). Different concentrations of both EOs (25 to 400 µg/mL) were mixed with human ejaculate and sperm motility was assessed after 5, 15 and 30 min. A total of 44 compounds were identified in MpEO; the major components were spathulenol, α-pinene, caryophyllene oxide, limonene and β-elemene. Both EOs exhibited spermostatic action in a dose-dependent manner. The best results were obtained for EbEO at all treatment times, showing IC 50 values of 454.75 µg/mL (5 min), 417.68 µg/mL (15 min) and 403.93 µg/mL (30 min). M. peruiferum also showed significant immobilizing potential with IC 50 values of 620.39 µg/mL (5 min), 652.70 µg/mL (15 min) and 579.37 µg/mL (30 min). Both oils showed low cytotoxicity against human erythrocytes. This is the first report on human spermostatic action for EOs from E. brejoensis and M. peruiferum which has antimicrobial activity and low cytotoxicity. These results suggest the need for further research on toxicological aspects of both EOs and their components in order to develop new pharmaceutical preparations using them as leader compounds.

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“…Most threatened medicinal plants are found in Jammu and Kashmir, followed by Sikkim, Himachal Pradesh, Arunachal Pradesh and Uttarakhand. Some of these endangered medicinal plants found in Himalayan region are Coptis teeta having anti-tumor and antibacterial activities, Gymnocladus assamicus used for treating swelling and abscesses, Illicium griffithii , an antifungal agent and food preservative, Lilium polyphyllum used for treating bronchial asthma and cough and Nardostachys jatamansi for epilepsy, and mental weakness [ 7 – 11 ]. Table 1 enlists some underutilized plants with both medicinal and agricultural benefits along with their geographical location in India.…”

Section: Geographical Distributionmentioning

confidence: 99%

Cultivation and conservation of underutilized medicinal and agricultural plants in India

Gupta

Kapila

2022

Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci.

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In the current era, the increased demand of healthy food rich in antioxidants, vitamins and minerals and those having therapeutic value has led to over-exploitation of major agricultural and medicinal plants. This overburden can be reduced by an efficient utilization of underutilized plants with nutritional and medicinal importance. These underutilized plants are neglected or undervalued ‘minor’ crops having low production and sale. These less documented and less studied group of underutilized plants are considered as a rich source of various phytochemicals and secondary metabolites having bioactive compounds. These underutilized wild herbs that have not gained much attention from commercial as well as scientific community were selected for the present study. The present review elucidates the significance of these plants and recent biotechnological methods to conserve them. The present study on such food and medically important herbs would contribute in a wide recognition of their benefits for our society.

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Essential oil constituents of Illicium griffithii and its antimicrobial activity

Cited by 10 publications

References 8 publications

Investigation of effect of 1,8-cineole on antimicrobial activity of chlorhexidine gluconate

Investigation of effect of 1,8-cineole on antimicrobial activity of chlorhexidine gluconate

Spermostatic activity of Eugenia brejoensis and Myroxylon peruiferum essential oils toward human spermatozoa

Cultivation and conservation of underutilized medicinal and agricultural plants in India

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