Complementary medicine has emerged with the history of humanity and has become widespread with the use of natural products in the treatment of many diseases. People have used many plant species in the treatment of diseases by benefiting from trial and error and knowledge. Plants have been used as shelter, food, medicine, spices, cosmetics, and tools for use in religious rituals. Different communities around the world have widely used local plants. In addition, the cosmopolitan species are used by all people in the treatment of diseases. Genus Salvia is a plant species that is widely known and used worldwide for its nutritional properties as well as its many biological activities. There are many secondary metabolites in different parts of the plant. Thanks to these secondary metabolites, it shows different biological properties. Salvia species have remarkable activities such as antioxidant, antimicrobial, anticancer. It is also an important natural resource with its high nutritional content. In this study, the nutritional contents, usage areas, chemical compositions and pharmacological properties of Genus Salvia were reviewed. In this context, the use of Salvia species in pharmacological designs and their nutritional importance were emphasized. As a result, it has been determined that members of Genus Salvia are one of the important plant species used in complementary medicine.