“…Additionally, uremia leading to the increased fragility of erythrocytes, shortened life-span of erythrocytes, gastro-intestinal bleeding in the form of haematemesis, melena, toxic metabolites is responsible for anemia in uremia. The causes of renal anemia include deficiency of erythropoietin (Desforges, 1970;Sikole, 2000;Yamaguchi-Yamada et al, 2004;Kaw andMalhotra, 2006 andLankhorst andWish, 2010) as the fundamental factor due to the damaged, non-functional nephrons (Bush, 1971) being incapable for erythropoietin production.…”